Matches in SemOpenAlex for { <https://semopenalex.org/work/W3186951060> ?p ?o ?g. }
- W3186951060 endingPage "915" @default.
- W3186951060 startingPage "915" @default.
- W3186951060 abstract "Atherosclerosis is a multifactorial chronic disease that has a prominent inflammatory component. Currently, atherosclerosis is regarded as an active autoimmune process that involves both innate and adaptive immune pathways. One of the drivers of this process is the presence of modified low-density lipoprotein (LDL). For instance, lipoprotein oxidation leads to the formation of oxidation-specific epitopes (OSE) that can be recognized by the immune cells. Macrophage response to OSEs is recognized as a key trigger for initiation and a stimulator of progression of the inflammatory process in the arteries. At the same time, the role of oxidized LDL components is not limited to pro-inflammatory stimulation, but includes immunoregulatory effects that can have protective functions. It is, therefore, important to better understand the complexity of oxidized LDL effects in atherosclerosis in order to develop new therapeutic approaches to correct the inflammatory and metabolic imbalance associated with this disorder. In this review, we discuss the process of oxidized LDL formation, mechanisms of OSE recognition by macrophages and the role of these processes in atherosclerosis." @default.
- W3186951060 created "2021-08-02" @default.
- W3186951060 creator A5008789435 @default.
- W3186951060 creator A5011643232 @default.
- W3186951060 creator A5029120395 @default.
- W3186951060 creator A5029819414 @default.
- W3186951060 creator A5035838886 @default.
- W3186951060 creator A5076329361 @default.
- W3186951060 date "2021-07-29" @default.
- W3186951060 modified "2023-10-09" @default.
- W3186951060 title "Recognition of Oxidized Lipids by Macrophages and Its Role in Atherosclerosis Development" @default.
- W3186951060 cites W1552425692 @default.
- W3186951060 cites W165179335 @default.
- W3186951060 cites W1724046836 @default.
- W3186951060 cites W1771958278 @default.
- W3186951060 cites W1797709486 @default.
- W3186951060 cites W1855877637 @default.
- W3186951060 cites W1959461807 @default.
- W3186951060 cites W1969319148 @default.
- W3186951060 cites W1971695807 @default.
- W3186951060 cites W1972483153 @default.
- W3186951060 cites W1972706930 @default.
- W3186951060 cites W1975905715 @default.
- W3186951060 cites W1976621212 @default.
- W3186951060 cites W1979201504 @default.
- W3186951060 cites W1985960306 @default.
- W3186951060 cites W1988859803 @default.
- W3186951060 cites W1991167353 @default.
- W3186951060 cites W1993545166 @default.
- W3186951060 cites W1999188820 @default.
- W3186951060 cites W2008311655 @default.
- W3186951060 cites W2015141049 @default.
- W3186951060 cites W2019346242 @default.
- W3186951060 cites W2027375896 @default.
- W3186951060 cites W2030557277 @default.
- W3186951060 cites W2030720809 @default.
- W3186951060 cites W2053312920 @default.
- W3186951060 cites W2053561492 @default.
- W3186951060 cites W2053874575 @default.
- W3186951060 cites W2056234470 @default.
- W3186951060 cites W2062097745 @default.
- W3186951060 cites W2063059344 @default.
- W3186951060 cites W2064760068 @default.
- W3186951060 cites W2066750024 @default.
- W3186951060 cites W2067531361 @default.
- W3186951060 cites W2072360089 @default.
- W3186951060 cites W2073548683 @default.
- W3186951060 cites W2076964782 @default.
- W3186951060 cites W2082400315 @default.
- W3186951060 cites W2098520810 @default.
- W3186951060 cites W2103647983 @default.
- W3186951060 cites W2112284458 @default.
- W3186951060 cites W2113492063 @default.
- W3186951060 cites W2113903712 @default.
- W3186951060 cites W2119499597 @default.
- W3186951060 cites W2121734411 @default.
- W3186951060 cites W2148989921 @default.
- W3186951060 cites W2150795824 @default.
- W3186951060 cites W2152415811 @default.
- W3186951060 cites W2154013127 @default.
- W3186951060 cites W2156613610 @default.
- W3186951060 cites W2163327518 @default.
- W3186951060 cites W2167132971 @default.
- W3186951060 cites W2167760404 @default.
- W3186951060 cites W2168897708 @default.
- W3186951060 cites W2171782802 @default.
- W3186951060 cites W2272435313 @default.
- W3186951060 cites W2283021481 @default.
- W3186951060 cites W2295011806 @default.
- W3186951060 cites W2395774853 @default.
- W3186951060 cites W2468517437 @default.
- W3186951060 cites W2509154958 @default.
- W3186951060 cites W2510604554 @default.
- W3186951060 cites W2590472357 @default.
- W3186951060 cites W2598976035 @default.
- W3186951060 cites W2601625032 @default.
- W3186951060 cites W2748400555 @default.
- W3186951060 cites W2758640170 @default.
- W3186951060 cites W2790580076 @default.
- W3186951060 cites W2801078348 @default.
- W3186951060 cites W2803800410 @default.
- W3186951060 cites W2806741586 @default.
- W3186951060 cites W2807678985 @default.
- W3186951060 cites W2887426837 @default.
- W3186951060 cites W2916952453 @default.
- W3186951060 cites W2924534120 @default.
- W3186951060 cites W2936100272 @default.
- W3186951060 cites W2949132973 @default.
- W3186951060 cites W2965570062 @default.
- W3186951060 cites W2974903901 @default.
- W3186951060 cites W2983142964 @default.
- W3186951060 cites W2987695377 @default.
- W3186951060 cites W2995149669 @default.
- W3186951060 cites W2997143234 @default.
- W3186951060 cites W3001462286 @default.
- W3186951060 cites W3003350845 @default.
- W3186951060 cites W3027855311 @default.
- W3186951060 cites W3031881950 @default.