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- W3187074063 abstract "The ability of chaperonins to buffer mutations that affect protein folding pathways suggests that their abundance should be evolutionarily advantageous. Here, we investigate the effect of chaperonin overproduction on cellular fitness in Escherichia coli . We demonstrate that chaperonin abundance confers 1) an ability to tolerate higher temperatures, 2) improved cellular fitness, and 3) enhanced folding of metabolic enzymes, which is expected to lead to enhanced energy harvesting potential." @default.
- W3187074063 created "2021-08-02" @default.
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- W3187074063 date "2021-07-26" @default.
- W3187074063 modified "2023-10-16" @default.
- W3187074063 title "Chaperonin Abundance Enhances Bacterial Fitness" @default.
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- W3187074063 doi "https://doi.org/10.3389/fmolb.2021.669996" @default.
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