Matches in SemOpenAlex for { <https://semopenalex.org/work/W3187130338> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W3187130338 abstract "Good's syndrome (GS) is a rare secondary immunodeficiency disease presenting as thymoma and hypogammaglobulinemia. Due to its rarity, the diagnosis of GS is often missed.We used the hospital information system to retrospectively screen thymoma and hypogammaglobulinemia patients at the First Affiliated Hospital of Wenzhou Medical University from Apr 2012 to Apr 2020. The clinical, laboratory, treatment, and outcome data for these patients were collected and analyzed.Among the 181 screened thymoma patients, 5 thymoma patients with hypogammaglobulinemia were identified; 3 patients had confirmed diagnoses of GS, and the other 2 did not have a diagnosis of GS recorded in the hospital information system. A retrospective review of the clinical characteristics, laboratory results, and follow-up data for these 2 undiagnosed patients confirmed the diagnosis of GS. All 5 GS patients presented with pneumonia, 2 patients presented with recurrent skin abscesses, 2 patients presented with recurrent cough and expectoration, 1 patient presented with recurrent oral lichen planus and diarrhea, and 1 patient presented with tuberculosis and granulomatous epididymitis. In the years after the diagnosis of hypogammaglobulinemia with mild symptoms, all 5 patients had received irregular intravenous immunoglobulin (IVIG) treatment. As the course of the disease progressed, the clinical symptoms of all patients worsened, but the symptoms were partly resolved with IVIG in these patients. However, 4 patients died due to comorbidities.GS should be investigated as a possible diagnosis in thymoma patients who present with hypogammaglobulinemia, especially those with recurrent opportunistic infections, recurrent skin abscesses, chronic diarrhea, or recurrent lichen planus." @default.
- W3187130338 created "2021-08-16" @default.
- W3187130338 creator A5003166126 @default.
- W3187130338 creator A5007412185 @default.
- W3187130338 creator A5026869217 @default.
- W3187130338 creator A5033448612 @default.
- W3187130338 creator A5039372448 @default.
- W3187130338 date "2021-08-03" @default.
- W3187130338 modified "2023-10-10" @default.
- W3187130338 title "Variable clinical characteristics and laboratory results in five patients with Chinese Good's syndrome (thymoma and hypogammaglobulinemia): an 8-year retrospective analysis in a university hospital in China" @default.
- W3187130338 cites W1755517158 @default.
- W3187130338 cites W1931850157 @default.
- W3187130338 cites W1971425506 @default.
- W3187130338 cites W2014181743 @default.
- W3187130338 cites W2067256429 @default.
- W3187130338 cites W2090836221 @default.
- W3187130338 cites W2117531097 @default.
- W3187130338 cites W2127403035 @default.
- W3187130338 cites W2134664435 @default.
- W3187130338 cites W2313687427 @default.
- W3187130338 cites W2405454803 @default.
- W3187130338 cites W2650504151 @default.
- W3187130338 cites W2892240084 @default.
- W3187130338 cites W2989023578 @default.
- W3187130338 doi "https://doi.org/10.1186/s12865-021-00441-9" @default.
- W3187130338 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8328998" @default.
- W3187130338 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34344301" @default.
- W3187130338 hasPublicationYear "2021" @default.
- W3187130338 type Work @default.
- W3187130338 sameAs 3187130338 @default.
- W3187130338 citedByCount "1" @default.
- W3187130338 countsByYear W31871303382023 @default.
- W3187130338 crossrefType "journal-article" @default.
- W3187130338 hasAuthorship W3187130338A5003166126 @default.
- W3187130338 hasAuthorship W3187130338A5007412185 @default.
- W3187130338 hasAuthorship W3187130338A5026869217 @default.
- W3187130338 hasAuthorship W3187130338A5033448612 @default.
- W3187130338 hasAuthorship W3187130338A5039372448 @default.
- W3187130338 hasBestOaLocation W31871303381 @default.
- W3187130338 hasConcept C126322002 @default.
- W3187130338 hasConcept C141071460 @default.
- W3187130338 hasConcept C159654299 @default.
- W3187130338 hasConcept C167135981 @default.
- W3187130338 hasConcept C187212893 @default.
- W3187130338 hasConcept C203014093 @default.
- W3187130338 hasConcept C2776433325 @default.
- W3187130338 hasConcept C2777607303 @default.
- W3187130338 hasConcept C2777805810 @default.
- W3187130338 hasConcept C2777914695 @default.
- W3187130338 hasConcept C2778105408 @default.
- W3187130338 hasConcept C2779159893 @default.
- W3187130338 hasConcept C2779615886 @default.
- W3187130338 hasConcept C71924100 @default.
- W3187130338 hasConcept C8891405 @default.
- W3187130338 hasConceptScore W3187130338C126322002 @default.
- W3187130338 hasConceptScore W3187130338C141071460 @default.
- W3187130338 hasConceptScore W3187130338C159654299 @default.
- W3187130338 hasConceptScore W3187130338C167135981 @default.
- W3187130338 hasConceptScore W3187130338C187212893 @default.
- W3187130338 hasConceptScore W3187130338C203014093 @default.
- W3187130338 hasConceptScore W3187130338C2776433325 @default.
- W3187130338 hasConceptScore W3187130338C2777607303 @default.
- W3187130338 hasConceptScore W3187130338C2777805810 @default.
- W3187130338 hasConceptScore W3187130338C2777914695 @default.
- W3187130338 hasConceptScore W3187130338C2778105408 @default.
- W3187130338 hasConceptScore W3187130338C2779159893 @default.
- W3187130338 hasConceptScore W3187130338C2779615886 @default.
- W3187130338 hasConceptScore W3187130338C71924100 @default.
- W3187130338 hasConceptScore W3187130338C8891405 @default.
- W3187130338 hasIssue "1" @default.
- W3187130338 hasLocation W31871303381 @default.
- W3187130338 hasLocation W31871303382 @default.
- W3187130338 hasLocation W31871303383 @default.
- W3187130338 hasOpenAccess W3187130338 @default.
- W3187130338 hasPrimaryLocation W31871303381 @default.
- W3187130338 hasRelatedWork W1994474377 @default.
- W3187130338 hasRelatedWork W2096513529 @default.
- W3187130338 hasRelatedWork W2406071546 @default.
- W3187130338 hasRelatedWork W2512602248 @default.
- W3187130338 hasRelatedWork W2575593447 @default.
- W3187130338 hasRelatedWork W2789153295 @default.
- W3187130338 hasRelatedWork W3128787947 @default.
- W3187130338 hasRelatedWork W3187130338 @default.
- W3187130338 hasRelatedWork W4362578129 @default.
- W3187130338 hasRelatedWork W4379375989 @default.
- W3187130338 hasVolume "22" @default.
- W3187130338 isParatext "false" @default.
- W3187130338 isRetracted "false" @default.
- W3187130338 magId "3187130338" @default.
- W3187130338 workType "article" @default.