FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3187152854> ?p ?o ?g. }

• W3187152854 abstract "Background: After the first COVID-19 infection wave, a constant increase of pulmonary embolism (PE) hospitalizations not linked with active PCR-confirmed COVID-19 was observed, but potential contributors to this observation are unclear. Therefore, we analyzed associations between changes in PE hospitalizations and (1) the incidence of non-COVID-19 pneumonia, (2) the use of computed tomography pulmonary angiography (CTPA), (3) volume depletion, and (4) preceding COVID-19 infection numbers in Germany. Methods: Claims data of Helios hospitals in Germany were used, and consecutive cases with a hospital admission between May 6 and December 15, 2020 (PE surplus period), were analyzed and compared to corresponding periods covering the same weeks in 2016–2019 (control period). We analyzed the number of PE cases in the target period with multivariable Poisson general linear mixed models (GLMM) including (a) cohorts of 2020 versus 2016–2019, (b) the number of cases with pneumonia, (c) CTPA, and (d) volume depletion and adjusted for age and sex. In order to associate the daily number of PE cases in 2020 with the number of preceding SARS-CoV-2 infections in Germany, we calculated the average number of daily infections (divided by 10,000) occurring between 14 up to 90 days with increasing window sizes before PE cases and modeled the data with Poisson regression. Results: There were 2,404 PE hospitalizations between May 6 and December 15, 2020, as opposed to 2,112–2,236 (total 8,717) in the corresponding 2016–2019 control periods (crude rate ratio [CRR] 1.10, 95% CI 1.05–1.15, P &lt; 0.01). With the use of multivariable Poisson GLMM adjusted for age, sex, and volume depletion, PE cases were significantly associated with the number of cases with pneumonia (CRR 1.09, 95% CI 1.07–1.10, P &lt; 0.01) and with CTPA (CRR 1.10, 95% CI 1.09–1.10, P &lt; 0.01). The increase of PE cases in 2020 compared with the control period remained significant (CRR 1.07, 95% CI 1.02–1.12, P &lt; 0.01) when controlling for those factors. In the 2020 cohort, the number of preceding average daily COVID-19 infections was associated with increased PE case incidence in all investigated windows, i.e., including preceding infections from 14 to 90 days. The best model (log likelihood −576) was with a window size of 4 days, i.e., average COVID-19 infections 14–17 days before PE hospitalization had a risk of 1.20 (95% CI 1.12–1.29, P &lt; 0.01). Conclusions: There is an increase in PE cases since early May 2020 compared to corresponding periods in 2016–2019. This surplus was significant even when controlling for changes in potential modulators such as demographics, volume depletion, non-COVID-19 pneumonia, CTPA use, and preceding COVID-19 infections. Future studies are needed (1) to investigate a potential causal link for increased risk of delayed PE with preceding SARS-CoV-2 infection and (2) to define optimal screening for SARS-CoV-2 in patients presenting with pneumonia and PE." @default.
• W3187152854 created "2021-08-16" @default.
• W3187152854 creator A5002039022 @default.
• W3187152854 creator A5011476849 @default.
• W3187152854 creator A5019758279 @default.
• W3187152854 creator A5024354264 @default.
• W3187152854 creator A5027906347 @default.
• W3187152854 creator A5035752353 @default.
• W3187152854 creator A5049710726 @default.
• W3187152854 creator A5069036914 @default.
• W3187152854 creator A5070141614 @default.
• W3187152854 date "2021-08-12" @default.
• W3187152854 modified "2023-10-16" @default.
• W3187152854 title "Potential Contributors to Increased Pulmonary Embolism Hospitalizations During the COVID-19 Pandemic: Insights From the German-Wide Helios Hospital Network" @default.
• W3187152854 cites W2041316235 @default.
• W3187152854 cites W2330949922 @default.
• W3187152854 cites W3108299043 @default.
• W3187152854 cites W3110284210 @default.
• W3187152854 cites W3124069563 @default.
• W3187152854 cites W3124900748 @default.
• W3187152854 cites W3134254938 @default.
• W3187152854 cites W3151702666 @default.
• W3187152854 doi "https://doi.org/10.3389/fcvm.2021.715761" @default.
• W3187152854 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8387932" @default.
• W3187152854 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34458341" @default.
• W3187152854 hasPublicationYear "2021" @default.
• W3187152854 type Work @default.
• W3187152854 sameAs 3187152854 @default.
• W3187152854 citedByCount "1" @default.
• W3187152854 countsByYear W31871528542022 @default.
• W3187152854 crossrefType "journal-article" @default.
• W3187152854 hasAuthorship W3187152854A5002039022 @default.
• W3187152854 hasAuthorship W3187152854A5011476849 @default.
• W3187152854 hasAuthorship W3187152854A5019758279 @default.
• W3187152854 hasAuthorship W3187152854A5024354264 @default.
• W3187152854 hasAuthorship W3187152854A5027906347 @default.
• W3187152854 hasAuthorship W3187152854A5035752353 @default.
• W3187152854 hasAuthorship W3187152854A5049710726 @default.
• W3187152854 hasAuthorship W3187152854A5069036914 @default.
• W3187152854 hasAuthorship W3187152854A5070141614 @default.
• W3187152854 hasBestOaLocation W31871528541 @default.
• W3187152854 hasConcept C100906024 @default.
• W3187152854 hasConcept C105795698 @default.
• W3187152854 hasConcept C116675565 @default.
• W3187152854 hasConcept C126322002 @default.
• W3187152854 hasConcept C144024400 @default.
• W3187152854 hasConcept C149923435 @default.
• W3187152854 hasConcept C159047783 @default.
• W3187152854 hasConcept C187212893 @default.
• W3187152854 hasConcept C194828623 @default.
• W3187152854 hasConcept C2524010 @default.
• W3187152854 hasConcept C2776265017 @default.
• W3187152854 hasConcept C2777914695 @default.
• W3187152854 hasConcept C2779134260 @default.
• W3187152854 hasConcept C2908647359 @default.
• W3187152854 hasConcept C3006700255 @default.
• W3187152854 hasConcept C3007834351 @default.
• W3187152854 hasConcept C3008058167 @default.
• W3187152854 hasConcept C33923547 @default.
• W3187152854 hasConcept C524204448 @default.
• W3187152854 hasConcept C61511704 @default.
• W3187152854 hasConcept C71924100 @default.
• W3187152854 hasConcept C73269764 @default.
• W3187152854 hasConcept C89623803 @default.
• W3187152854 hasConcept C99454951 @default.
• W3187152854 hasConceptScore W3187152854C100906024 @default.
• W3187152854 hasConceptScore W3187152854C105795698 @default.
• W3187152854 hasConceptScore W3187152854C116675565 @default.
• W3187152854 hasConceptScore W3187152854C126322002 @default.
• W3187152854 hasConceptScore W3187152854C144024400 @default.
• W3187152854 hasConceptScore W3187152854C149923435 @default.
• W3187152854 hasConceptScore W3187152854C159047783 @default.
• W3187152854 hasConceptScore W3187152854C187212893 @default.
• W3187152854 hasConceptScore W3187152854C194828623 @default.
• W3187152854 hasConceptScore W3187152854C2524010 @default.
• W3187152854 hasConceptScore W3187152854C2776265017 @default.
• W3187152854 hasConceptScore W3187152854C2777914695 @default.
• W3187152854 hasConceptScore W3187152854C2779134260 @default.
• W3187152854 hasConceptScore W3187152854C2908647359 @default.
• W3187152854 hasConceptScore W3187152854C3006700255 @default.
• W3187152854 hasConceptScore W3187152854C3007834351 @default.
• W3187152854 hasConceptScore W3187152854C3008058167 @default.
• W3187152854 hasConceptScore W3187152854C33923547 @default.
• W3187152854 hasConceptScore W3187152854C524204448 @default.
• W3187152854 hasConceptScore W3187152854C61511704 @default.
• W3187152854 hasConceptScore W3187152854C71924100 @default.
• W3187152854 hasConceptScore W3187152854C73269764 @default.
• W3187152854 hasConceptScore W3187152854C89623803 @default.
• W3187152854 hasConceptScore W3187152854C99454951 @default.
• W3187152854 hasFunder F4320320882 @default.
• W3187152854 hasLocation W31871528541 @default.
• W3187152854 hasLocation W31871528542 @default.
• W3187152854 hasLocation W31871528543 @default.
• W3187152854 hasLocation W31871528544 @default.
• W3187152854 hasOpenAccess W3187152854 @default.
• W3187152854 hasPrimaryLocation W31871528541 @default.
• W3187152854 hasRelatedWork W3012050440 @default.
• W3187152854 hasRelatedWork W3017171836 @default.
• W3187152854 hasRelatedWork W3025176011 @default.
• W3187152854 hasRelatedWork W3027835066 @default.

• next