Matches in SemOpenAlex for { <https://semopenalex.org/work/W3187315806> ?p ?o ?g. }
- W3187315806 abstract "Abstract The purpose of this exploratory research is to provide data on synaptopathy in the behavioral variant of frontotemporal dementia (bvFTD). Twelve patients with probable bvFTD were compared to 12 control participants and 12 patients with Alzheimer’s disease (AD). Loss of synaptic projections was assessed with [ 18 F]UCBH-PET. Total distribution volume was obtained with Logan method using carotid artery derived input function. Neuroimages were analyzed with SPM12. Verbal fluency, episodic memory and awareness of cognitive impairment were equally impaired in patients groups. Compared to controls, [ 18 F]UCBH uptake tended to decrease in the right anterior parahippocampal gyrus of bvFTD patients. Loss of synaptic projections was observed in the right hippocampus of AD participants, but there was no significant difference in [ 18 F]UCBH brain uptake between patients groups. Anosognosia for clinical disorder was correlated with synaptic density in the caudate nucleus and the anteromedial prefrontal cortex. This study suggests that synaptopathy in bvFTD targets the temporal social brain and self-referential processes." @default.
- W3187315806 created "2021-08-16" @default.
- W3187315806 creator A5001306214 @default.
- W3187315806 creator A5006933724 @default.
- W3187315806 creator A5013091803 @default.
- W3187315806 creator A5020428601 @default.
- W3187315806 creator A5028247688 @default.
- W3187315806 creator A5030854402 @default.
- W3187315806 creator A5053619356 @default.
- W3187315806 creator A5054096836 @default.
- W3187315806 creator A5056248131 @default.
- W3187315806 creator A5062003959 @default.
- W3187315806 creator A5087211088 @default.
- W3187315806 date "2021-08-09" @default.
- W3187315806 modified "2023-10-01" @default.
- W3187315806 title "In vivo exploration of synaptic projections in frontotemporal dementia" @default.
- W3187315806 cites W1482549097 @default.
- W3187315806 cites W1626555178 @default.
- W3187315806 cites W1968692604 @default.
- W3187315806 cites W1970863948 @default.
- W3187315806 cites W1976601956 @default.
- W3187315806 cites W1977618591 @default.
- W3187315806 cites W1979298827 @default.
- W3187315806 cites W1983183519 @default.
- W3187315806 cites W1999030539 @default.
- W3187315806 cites W2007804566 @default.
- W3187315806 cites W2012479750 @default.
- W3187315806 cites W2013289301 @default.
- W3187315806 cites W2013743080 @default.
- W3187315806 cites W2015808525 @default.
- W3187315806 cites W2021401325 @default.
- W3187315806 cites W2021714056 @default.
- W3187315806 cites W2026273357 @default.
- W3187315806 cites W2031939736 @default.
- W3187315806 cites W2032426886 @default.
- W3187315806 cites W2041615438 @default.
- W3187315806 cites W2042951607 @default.
- W3187315806 cites W2043242347 @default.
- W3187315806 cites W2043260356 @default.
- W3187315806 cites W2044766870 @default.
- W3187315806 cites W2061834258 @default.
- W3187315806 cites W2062827097 @default.
- W3187315806 cites W2079309705 @default.
- W3187315806 cites W2079499736 @default.
- W3187315806 cites W2099375457 @default.
- W3187315806 cites W2101334128 @default.
- W3187315806 cites W2105071925 @default.
- W3187315806 cites W2115017507 @default.
- W3187315806 cites W2119285123 @default.
- W3187315806 cites W2128030851 @default.
- W3187315806 cites W2136250824 @default.
- W3187315806 cites W2137404280 @default.
- W3187315806 cites W2144854908 @default.
- W3187315806 cites W2147948236 @default.
- W3187315806 cites W2148879703 @default.
- W3187315806 cites W2164402329 @default.
- W3187315806 cites W2170469453 @default.
- W3187315806 cites W2176830446 @default.
- W3187315806 cites W2306720010 @default.
- W3187315806 cites W2511373877 @default.
- W3187315806 cites W2522684824 @default.
- W3187315806 cites W2542549468 @default.
- W3187315806 cites W2609315787 @default.
- W3187315806 cites W2752170792 @default.
- W3187315806 cites W2758291356 @default.
- W3187315806 cites W2766970894 @default.
- W3187315806 cites W2770547283 @default.
- W3187315806 cites W2883737562 @default.
- W3187315806 cites W2904180113 @default.
- W3187315806 cites W2907341743 @default.
- W3187315806 cites W2933363539 @default.
- W3187315806 cites W2943930324 @default.
- W3187315806 cites W2969859326 @default.
- W3187315806 cites W2987657931 @default.
- W3187315806 cites W2997938254 @default.
- W3187315806 cites W3015522591 @default.
- W3187315806 cites W3025834426 @default.
- W3187315806 cites W3166602195 @default.
- W3187315806 cites W4230920194 @default.
- W3187315806 cites W4295750005 @default.
- W3187315806 doi "https://doi.org/10.1038/s41598-021-95499-1" @default.
- W3187315806 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8352914" @default.
- W3187315806 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34373529" @default.
- W3187315806 hasPublicationYear "2021" @default.
- W3187315806 type Work @default.
- W3187315806 sameAs 3187315806 @default.
- W3187315806 citedByCount "9" @default.
- W3187315806 countsByYear W31873158062022 @default.
- W3187315806 countsByYear W31873158062023 @default.
- W3187315806 crossrefType "journal-article" @default.
- W3187315806 hasAuthorship W3187315806A5001306214 @default.
- W3187315806 hasAuthorship W3187315806A5006933724 @default.
- W3187315806 hasAuthorship W3187315806A5013091803 @default.
- W3187315806 hasAuthorship W3187315806A5020428601 @default.
- W3187315806 hasAuthorship W3187315806A5028247688 @default.
- W3187315806 hasAuthorship W3187315806A5030854402 @default.
- W3187315806 hasAuthorship W3187315806A5053619356 @default.
- W3187315806 hasAuthorship W3187315806A5054096836 @default.
- W3187315806 hasAuthorship W3187315806A5056248131 @default.
- W3187315806 hasAuthorship W3187315806A5062003959 @default.