FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3187533283> ?p ?o ?g. }

• W3187533283 endingPage "8181" @default.
• W3187533283 startingPage "8181" @default.
• W3187533283 abstract "The distribution of differential extracellular matrix (ECM) in the lateral and medial menisci can contribute to knee instability, and changes in the meniscus tissue can lead to joint disease. Thus, deep proteomic identification of the lateral and medial meniscus cartilage is expected to provide important information for treatment and diagnosis of various knee joint diseases. We investigated the proteomic profiles of 12 lateral/medial meniscus pairs obtained from excess tissue of osteoarthritis patients who underwent knee arthroscopy surgery using mass spectrometry-based techniques and measured 75 ECM protein levels in the lesions using a multiple reaction monitoring (MRM) assay we developed. A total of 906 meniscus proteins with a 1% false discovery rate (FDR) was identified through a tandem mass tag (TMT) analysis showing that the lateral and medial menisci had similar protein expression profiles. A total of 131 ECM-related proteins was included in meniscus tissues such as collagen, fibronectin, and laminin. Our data showed that 14 ECM protein levels were differentially expressed in lateral and medial lesions (p < 0.05). We present the proteomic characterization of meniscal tissue with mass spectrometry-based comparative proteomic analysis and developed an MRM-based assay of ECM proteins correlated with tissue regeneration. The mass spectrometry dataset has been deposited to the MassIVE repository with the dataset identifier MSV000087753." @default.
• W3187533283 created "2021-08-16" @default.
• W3187533283 creator A5013047009 @default.
• W3187533283 creator A5025086129 @default.
• W3187533283 creator A5032373973 @default.
• W3187533283 creator A5056899449 @default.
• W3187533283 creator A5062071958 @default.
• W3187533283 creator A5075462954 @default.
• W3187533283 creator A5076839463 @default.
• W3187533283 date "2021-07-30" @default.
• W3187533283 modified "2023-10-16" @default.
• W3187533283 title "Proteomic Analysis of the Meniscus Cartilage in Osteoarthritis" @default.
• W3187533283 cites W2003328208 @default.
• W3187533283 cites W2037199116 @default.
• W3187533283 cites W2096951773 @default.
• W3187533283 cites W2110346993 @default.
• W3187533283 cites W2124037583 @default.
• W3187533283 cites W2268595126 @default.
• W3187533283 cites W2869488255 @default.
• W3187533283 cites W2902215912 @default.
• W3187533283 cites W2906246413 @default.
• W3187533283 cites W2908179602 @default.
• W3187533283 cites W2944633184 @default.
• W3187533283 cites W2968243186 @default.
• W3187533283 cites W3003343568 @default.
• W3187533283 doi "https://doi.org/10.3390/ijms22158181" @default.
• W3187533283 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8348647" @default.
• W3187533283 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34360947" @default.
• W3187533283 hasPublicationYear "2021" @default.
• W3187533283 type Work @default.
• W3187533283 sameAs 3187533283 @default.
• W3187533283 citedByCount "3" @default.
• W3187533283 countsByYear W31875332832022 @default.
• W3187533283 countsByYear W31875332832023 @default.
• W3187533283 crossrefType "journal-article" @default.
• W3187533283 hasAuthorship W3187533283A5013047009 @default.
• W3187533283 hasAuthorship W3187533283A5025086129 @default.
• W3187533283 hasAuthorship W3187533283A5032373973 @default.
• W3187533283 hasAuthorship W3187533283A5056899449 @default.
• W3187533283 hasAuthorship W3187533283A5062071958 @default.
• W3187533283 hasAuthorship W3187533283A5075462954 @default.
• W3187533283 hasAuthorship W3187533283A5076839463 @default.
• W3187533283 hasBestOaLocation W31875332831 @default.
• W3187533283 hasConcept C104317684 @default.
• W3187533283 hasConcept C105702510 @default.
• W3187533283 hasConcept C120665830 @default.
• W3187533283 hasConcept C121332964 @default.
• W3187533283 hasConcept C142724271 @default.
• W3187533283 hasConcept C162356407 @default.
• W3187533283 hasConcept C185592680 @default.
• W3187533283 hasConcept C189165786 @default.
• W3187533283 hasConcept C189178095 @default.
• W3187533283 hasConcept C204787440 @default.
• W3187533283 hasConcept C24066741 @default.
• W3187533283 hasConcept C2776164576 @default.
• W3187533283 hasConcept C2780423099 @default.
• W3187533283 hasConcept C2780550940 @default.
• W3187533283 hasConcept C31827203 @default.
• W3187533283 hasConcept C43617362 @default.
• W3187533283 hasConcept C46111723 @default.
• W3187533283 hasConcept C55493867 @default.
• W3187533283 hasConcept C61511704 @default.
• W3187533283 hasConcept C71924100 @default.
• W3187533283 hasConcept C86492073 @default.
• W3187533283 hasConceptScore W3187533283C104317684 @default.
• W3187533283 hasConceptScore W3187533283C105702510 @default.
• W3187533283 hasConceptScore W3187533283C120665830 @default.
• W3187533283 hasConceptScore W3187533283C121332964 @default.
• W3187533283 hasConceptScore W3187533283C142724271 @default.
• W3187533283 hasConceptScore W3187533283C162356407 @default.
• W3187533283 hasConceptScore W3187533283C185592680 @default.
• W3187533283 hasConceptScore W3187533283C189165786 @default.
• W3187533283 hasConceptScore W3187533283C189178095 @default.
• W3187533283 hasConceptScore W3187533283C204787440 @default.
• W3187533283 hasConceptScore W3187533283C24066741 @default.
• W3187533283 hasConceptScore W3187533283C2776164576 @default.
• W3187533283 hasConceptScore W3187533283C2780423099 @default.
• W3187533283 hasConceptScore W3187533283C2780550940 @default.
• W3187533283 hasConceptScore W3187533283C31827203 @default.
• W3187533283 hasConceptScore W3187533283C43617362 @default.
• W3187533283 hasConceptScore W3187533283C46111723 @default.
• W3187533283 hasConceptScore W3187533283C55493867 @default.
• W3187533283 hasConceptScore W3187533283C61511704 @default.
• W3187533283 hasConceptScore W3187533283C71924100 @default.
• W3187533283 hasConceptScore W3187533283C86492073 @default.
• W3187533283 hasIssue "15" @default.
• W3187533283 hasLocation W31875332831 @default.
• W3187533283 hasLocation W31875332832 @default.
• W3187533283 hasOpenAccess W3187533283 @default.
• W3187533283 hasPrimaryLocation W31875332831 @default.
• W3187533283 hasRelatedWork W1964703555 @default.
• W3187533283 hasRelatedWork W1965432215 @default.
• W3187533283 hasRelatedWork W2043328205 @default.
• W3187533283 hasRelatedWork W2079674236 @default.
• W3187533283 hasRelatedWork W2278142178 @default.
• W3187533283 hasRelatedWork W2507663100 @default.
• W3187533283 hasRelatedWork W2912790277 @default.
• W3187533283 hasRelatedWork W2968347375 @default.

• next