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- W3187907610 endingPage "3063" @default.
- W3187907610 startingPage "3051" @default.
- W3187907610 abstract "Acanthamoeba spp. are among the most worldwide prevalent protozoa. It is the causative agent of a disease known as Acanthamoeba keratitis, a painful and severe sight-threatening corneal infection that can lead to blindness. In recent years, the prevalence of Acanthamoeba keratitis has rapidly increased, growing its importance to human health. This systematic review aims to assess the distribution of Acanthamoeba sp. genotypes causing keratitis around the world, considering the sample collected type and the used identification method. Most of the cases were found in Asia and Europe. Not surprisingly, the T4 genotype was the most prevalent worldwide, followed by T3, T15, T11, and T5. Furthermore, the T4 genotype contains a higher number of species. Given the differences in pathology, susceptibility to treatment, and clinical outcome between distinct genotypes, it is essential to genotype isolates from Acanthamoeba keratitis cases to help to establish a better correlation between in vitro and in vivo activities, resulting in better drug therapies and successful treatment in cases of this important ocular infection." @default.
- W3187907610 created "2021-08-16" @default.
- W3187907610 creator A5003446326 @default.
- W3187907610 creator A5010905820 @default.
- W3187907610 creator A5085884496 @default.
- W3187907610 date "2021-08-05" @default.
- W3187907610 modified "2023-10-16" @default.
- W3187907610 title "Genotype distribution of Acanthamoeba in keratitis: a systematic review" @default.
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