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- W3187956989 abstract "Atopic dermatitis is a common, chronic and recurrent inflammatory skin disease, which often appears in childhood but can last into adulthood. It negatively impacts patients, their families and society in general. There is a therapeutic unmet need, with patients requiring new drugs that are safe and effective. The increasing knowledge of the pathophysiology of AD and the role of the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway in the development and maintenance of AD, has led to the development of agents blocking this intracellular signaling pathway, the JAK inhibitors. Baricitinib shows high selectivity for JAK1 and JAK2, making it appealing for the treatment of this condition. Phase II and phase III trials evaluated the efficacy and safety of baricitinib in the treatment of AD, and the results have been encouraging, showing a good efficacy and a favorable safety and tolerability profile. At the end of 2020, EMA approved baricitinib for the treatment of adult patients with moderate-to-severe atopic dermatitis who are candidates for systemic therapy, increasing the therapeutic option for this debilitating disease." @default.
- W3187956989 created "2021-08-16" @default.
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- W3187956989 date "2021-08-23" @default.
- W3187956989 modified "2023-10-14" @default.
- W3187956989 title "Baricitinib for the treatment of atopic dermatitis" @default.
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- W3187956989 cites W1527957830 @default.
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- W3187956989 cites W1572255065 @default.
- W3187956989 cites W1580233091 @default.
- W3187956989 cites W1605295219 @default.
- W3187956989 cites W1678127861 @default.
- W3187956989 cites W1858234123 @default.
- W3187956989 cites W189068515 @default.
- W3187956989 cites W1965679398 @default.
- W3187956989 cites W1969693921 @default.
- W3187956989 cites W1969725546 @default.
- W3187956989 cites W1970546858 @default.
- W3187956989 cites W1974004014 @default.
- W3187956989 cites W1975165863 @default.
- W3187956989 cites W1975438745 @default.
- W3187956989 cites W1980040943 @default.
- W3187956989 cites W1982385791 @default.
- W3187956989 cites W1983218074 @default.
- W3187956989 cites W1983695621 @default.
- W3187956989 cites W1988035869 @default.
- W3187956989 cites W1991660645 @default.
- W3187956989 cites W1994262603 @default.
- W3187956989 cites W1998116294 @default.
- W3187956989 cites W2005359518 @default.
- W3187956989 cites W2007464650 @default.
- W3187956989 cites W2008810664 @default.
- W3187956989 cites W2021705314 @default.
- W3187956989 cites W2027262352 @default.
- W3187956989 cites W2044053588 @default.
- W3187956989 cites W2051918905 @default.
- W3187956989 cites W2059510873 @default.
- W3187956989 cites W2060663996 @default.
- W3187956989 cites W2065746239 @default.
- W3187956989 cites W2068176013 @default.
- W3187956989 cites W2092750645 @default.
- W3187956989 cites W2094036101 @default.
- W3187956989 cites W2106551918 @default.
- W3187956989 cites W2132173287 @default.
- W3187956989 cites W2140192959 @default.
- W3187956989 cites W2142327072 @default.
- W3187956989 cites W2159659449 @default.
- W3187956989 cites W2160136847 @default.
- W3187956989 cites W2164098277 @default.
- W3187956989 cites W2200308911 @default.
- W3187956989 cites W2479513966 @default.
- W3187956989 cites W2508602922 @default.
- W3187956989 cites W2520198258 @default.
- W3187956989 cites W2595942898 @default.
- W3187956989 cites W2601742683 @default.
- W3187956989 cites W2610814011 @default.
- W3187956989 cites W2753400148 @default.
- W3187956989 cites W2755633626 @default.
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- W3187956989 cites W2790024164 @default.
- W3187956989 cites W2790260386 @default.
- W3187956989 cites W2810369524 @default.
- W3187956989 cites W283007130 @default.
- W3187956989 cites W2886980930 @default.
- W3187956989 cites W2904559265 @default.
- W3187956989 cites W2906224434 @default.
- W3187956989 cites W2940853643 @default.
- W3187956989 cites W2999573960 @default.
- W3187956989 cites W3003334583 @default.
- W3187956989 cites W3046346811 @default.
- W3187956989 cites W3048673809 @default.
- W3187956989 cites W3087665791 @default.
- W3187956989 cites W3089470786 @default.
- W3187956989 cites W3129325639 @default.
- W3187956989 cites W3163616100 @default.
- W3187956989 cites W4210971299 @default.
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- W3187956989 cites W4230355606 @default.
- W3187956989 cites W4232685799 @default.
- W3187956989 cites W4244585549 @default.
- W3187956989 cites W4251944893 @default.
- W3187956989 cites W4366807517 @default.
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- W3187956989 doi "https://doi.org/10.1080/09546634.2021.1967268" @default.
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