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• W3188174739 abstract "Coil compaction is directly related to the degree of cerebral aneurysmal recanalization. The degree of recanalization (DoR) was quantified by measuring the volume vacated by coil deformation. The purpose of this study was to clarify the hemodynamic and morphologic factors associated with coil compaction. Computational fluid dynamics simulations were performed on 28 middle-size (5–10 mm) unruptured basilar artery tip aneurysms. The DoR was measured by comparing the coil mass shape obtained from three-dimensional digital subtraction angiography data immediately after coil embolization and again within 1–2 years of follow-up. Deployed coils were modeled using a virtual coiling technique for computational fluid dynamics simulations. Hemodynamic and morphologic factors to predict the DoR were derived using multiple linear regression. Aneurysmal neck area, the maximum pressure generated on the neck surface after coil embolization, and the high-pressure position on the neck surface predicted DoR with statistic significance (P < 0.001, P < 0.001, P = 0.004, respectively). The DoR tended to increase when the neck area was large, the pressure generated on the coils was high, and the high-pressure position was close to the center of the neck surface. The volume embolization ratio was not statistically relevant for the DoR in the cases of this study. Coil compaction occurs in cerebral aneurysms with a wide neck, high pressure generated on the coils, and high pressure in the center of the neck surface. Establishing the DoR can contribute to the prediction of recanalization after coil embolization." @default.
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• W3188174739 date "2021-08-01" @default.
• W3188174739 modified "2023-09-26" @default.
• W3188174739 title "Hemodynamic and Morphologic Factors Related to Coil Compaction in Basilar Artery Tip Aneurysms" @default.
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• W3188174739 doi "https://doi.org/10.1016/j.wneu.2021.08.011" @default.
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