Matches in SemOpenAlex for { <https://semopenalex.org/work/W3188793075> ?p ?o ?g. }
- W3188793075 endingPage "e100411" @default.
- W3188793075 startingPage "e100411" @default.
- W3188793075 abstract "Adolescence is the peak period for the incidence of anxiety disorders. Recent findings have revealed the immaturity of neural networks underlying emotional regulation in this population. Brain vulnerability to anxiety in adolescence is related to the unsynchronised development of anxiety-relevant brain functional systems. However, our current knowledge on brain deficits in adolescent anxiety is mainly borrowed from studies on adults. Understanding adolescent-specific brain deficits is essential for developing biomarkers and brain-based therapies targeting adolescent anxiety. This article reviews and compares recent neuroimaging literature on anxiety-related brain structural and functional deficits between adolescent and adult populations, and proposes a model highlighting the differences between adolescence and adulthood in anxiety-related brain networks. This model emphasises that in adolescence the emotional control system tends to be hypoactivated, the fear conditioning system is immature, and the reward and stress response systems are hypersensitive. Furthermore, the striatum's functional links to the amygdala and the prefrontal cortex are strengthened, while the link between the prefrontal cortex and the amygdala is weakened in adolescence. This model helps to explain why adolescents are vulnerable to anxiety disorders and provides insights into potential brain-based approaches to intervene in adolescent anxiety disorders." @default.
- W3188793075 created "2021-08-16" @default.
- W3188793075 creator A5006006441 @default.
- W3188793075 creator A5048840363 @default.
- W3188793075 creator A5060249034 @default.
- W3188793075 creator A5081020222 @default.
- W3188793075 date "2021-08-01" @default.
- W3188793075 modified "2023-10-16" @default.
- W3188793075 title "Adolescent anxiety disorders and the developing brain: comparing neuroimaging findings in adolescents and adults" @default.
- W3188793075 cites W1015756911 @default.
- W3188793075 cites W1517665341 @default.
- W3188793075 cites W1547865271 @default.
- W3188793075 cites W1579693295 @default.
- W3188793075 cites W1695265315 @default.
- W3188793075 cites W1946212440 @default.
- W3188793075 cites W1972308065 @default.
- W3188793075 cites W1973438804 @default.
- W3188793075 cites W1977502547 @default.
- W3188793075 cites W1982958140 @default.
- W3188793075 cites W1985661446 @default.
- W3188793075 cites W1990397347 @default.
- W3188793075 cites W1992630689 @default.
- W3188793075 cites W1993400322 @default.
- W3188793075 cites W1997982013 @default.
- W3188793075 cites W1999217070 @default.
- W3188793075 cites W2000064859 @default.
- W3188793075 cites W2003598308 @default.
- W3188793075 cites W2003647722 @default.
- W3188793075 cites W2004304018 @default.
- W3188793075 cites W2004873925 @default.
- W3188793075 cites W2005559664 @default.
- W3188793075 cites W2013728545 @default.
- W3188793075 cites W2015965964 @default.
- W3188793075 cites W2018187876 @default.
- W3188793075 cites W2019461690 @default.
- W3188793075 cites W2032125220 @default.
- W3188793075 cites W2034448215 @default.
- W3188793075 cites W2040562680 @default.
- W3188793075 cites W2047582613 @default.
- W3188793075 cites W2049830989 @default.
- W3188793075 cites W2050753235 @default.
- W3188793075 cites W2069090835 @default.
- W3188793075 cites W2070834016 @default.
- W3188793075 cites W2072093845 @default.
- W3188793075 cites W2073718251 @default.
- W3188793075 cites W2088648420 @default.
- W3188793075 cites W2092702461 @default.
- W3188793075 cites W2095005872 @default.
- W3188793075 cites W2109181684 @default.
- W3188793075 cites W2115261275 @default.
- W3188793075 cites W2123437610 @default.
- W3188793075 cites W2124526585 @default.
- W3188793075 cites W2126520022 @default.
- W3188793075 cites W2128472904 @default.
- W3188793075 cites W2144586633 @default.
- W3188793075 cites W2145309562 @default.
- W3188793075 cites W2155647121 @default.
- W3188793075 cites W2165478810 @default.
- W3188793075 cites W2165709961 @default.
- W3188793075 cites W2166670920 @default.
- W3188793075 cites W2176365174 @default.
- W3188793075 cites W2238546778 @default.
- W3188793075 cites W2254443919 @default.
- W3188793075 cites W2298519801 @default.
- W3188793075 cites W2304092127 @default.
- W3188793075 cites W2341692630 @default.
- W3188793075 cites W2343366531 @default.
- W3188793075 cites W2400483370 @default.
- W3188793075 cites W2403584403 @default.
- W3188793075 cites W2410502852 @default.
- W3188793075 cites W2461785184 @default.
- W3188793075 cites W2505575367 @default.
- W3188793075 cites W2518532783 @default.
- W3188793075 cites W2566224336 @default.
- W3188793075 cites W2586104651 @default.
- W3188793075 cites W2609967814 @default.
- W3188793075 cites W2732643414 @default.
- W3188793075 cites W2732817546 @default.
- W3188793075 cites W2748791900 @default.
- W3188793075 cites W2755732590 @default.
- W3188793075 cites W2769665590 @default.
- W3188793075 cites W2774011664 @default.
- W3188793075 cites W2782498233 @default.
- W3188793075 cites W2788341270 @default.
- W3188793075 cites W2795560474 @default.
- W3188793075 cites W2802155330 @default.
- W3188793075 cites W2901592350 @default.
- W3188793075 cites W2916035804 @default.
- W3188793075 cites W2916226351 @default.
- W3188793075 cites W2917576966 @default.
- W3188793075 cites W2921355666 @default.
- W3188793075 cites W2928149567 @default.
- W3188793075 cites W2946606732 @default.
- W3188793075 cites W2949788162 @default.
- W3188793075 cites W2953812304 @default.
- W3188793075 cites W2956101215 @default.
- W3188793075 cites W2967916005 @default.
- W3188793075 cites W2985075209 @default.