Matches in SemOpenAlex for { <https://semopenalex.org/work/W3188869439> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W3188869439 abstract "When bacteria are exposed to chronic or cyclic irradiation with ultraviolet (UV) light, it is observed that their resistance to this agent is increased by the selection of advantageous mutations under those conditions. UV light produces different damages in DNA, the repair of which is necessary to maintain the integrity of the genome. However, some damages can lead to such mutations when they are not properly repaired. In an earlier work, five subcultures of a wild-type Escherichia coli strain (PQ30) were cyclically irradiated with UV and different strains resistant to UV light and gamma radiation were obtained. In a preliminary mapping, different genes involved in their resistance to radiation were identified. In one of these strains, designated as IN801, the radA gene, the product of which is involved in recombinational DNA repair, was identified. In this work, cells from another wild-type strain (AB1157) were transformed with a plasmid (pUC19) that carries the radA gene from either PQ30 or IN801, in order to establish whether the radio-resistant phenotype can be transferred to a normal strain. Only cells that received the IN801 radA gene showed increased resistance to UV and gamma radiation. Further radA sequencing showed that the gene of IN801 acquired two-point mutations that replace two amino acids in the RadA protein, which most likely changed its enzymatic activities. These results confirm that radA participates in the radiation resistance of IN801." @default.
- W3188869439 created "2021-08-16" @default.
- W3188869439 creator A5010514638 @default.
- W3188869439 creator A5048034700 @default.
- W3188869439 creator A5060356240 @default.
- W3188869439 creator A5071599983 @default.
- W3188869439 date "2021-08-03" @default.
- W3188869439 modified "2023-10-14" @default.
- W3188869439 title "MUTATIONS IN radA ARE RESPONSIBLE FOR ACQUIRED RADIO-RESISTANCE IN AN Escherichia coli STRAIN" @default.
- W3188869439 doi "https://doi.org/10.20937/rica.53864" @default.
- W3188869439 hasPublicationYear "2021" @default.
- W3188869439 type Work @default.
- W3188869439 sameAs 3188869439 @default.
- W3188869439 citedByCount "0" @default.
- W3188869439 crossrefType "journal-article" @default.
- W3188869439 hasAuthorship W3188869439A5010514638 @default.
- W3188869439 hasAuthorship W3188869439A5048034700 @default.
- W3188869439 hasAuthorship W3188869439A5060356240 @default.
- W3188869439 hasAuthorship W3188869439A5071599983 @default.
- W3188869439 hasBestOaLocation W31888694391 @default.
- W3188869439 hasConcept C104317684 @default.
- W3188869439 hasConcept C105702510 @default.
- W3188869439 hasConcept C143065580 @default.
- W3188869439 hasConcept C153911025 @default.
- W3188869439 hasConcept C185592680 @default.
- W3188869439 hasConcept C22744801 @default.
- W3188869439 hasConcept C2778022156 @default.
- W3188869439 hasConcept C2987116853 @default.
- W3188869439 hasConcept C501734568 @default.
- W3188869439 hasConcept C54355233 @default.
- W3188869439 hasConcept C547475151 @default.
- W3188869439 hasConcept C75473681 @default.
- W3188869439 hasConcept C86803240 @default.
- W3188869439 hasConcept C89423630 @default.
- W3188869439 hasConceptScore W3188869439C104317684 @default.
- W3188869439 hasConceptScore W3188869439C105702510 @default.
- W3188869439 hasConceptScore W3188869439C143065580 @default.
- W3188869439 hasConceptScore W3188869439C153911025 @default.
- W3188869439 hasConceptScore W3188869439C185592680 @default.
- W3188869439 hasConceptScore W3188869439C22744801 @default.
- W3188869439 hasConceptScore W3188869439C2778022156 @default.
- W3188869439 hasConceptScore W3188869439C2987116853 @default.
- W3188869439 hasConceptScore W3188869439C501734568 @default.
- W3188869439 hasConceptScore W3188869439C54355233 @default.
- W3188869439 hasConceptScore W3188869439C547475151 @default.
- W3188869439 hasConceptScore W3188869439C75473681 @default.
- W3188869439 hasConceptScore W3188869439C86803240 @default.
- W3188869439 hasConceptScore W3188869439C89423630 @default.
- W3188869439 hasLocation W31888694391 @default.
- W3188869439 hasOpenAccess W3188869439 @default.
- W3188869439 hasPrimaryLocation W31888694391 @default.
- W3188869439 hasRelatedWork W14819275 @default.
- W3188869439 hasRelatedWork W19731819 @default.
- W3188869439 hasRelatedWork W20210608 @default.
- W3188869439 hasRelatedWork W23205882 @default.
- W3188869439 hasRelatedWork W28984920 @default.
- W3188869439 hasRelatedWork W30829945 @default.
- W3188869439 hasRelatedWork W35642217 @default.
- W3188869439 hasRelatedWork W36097424 @default.
- W3188869439 hasRelatedWork W37832647 @default.
- W3188869439 hasRelatedWork W4956182 @default.
- W3188869439 isParatext "false" @default.
- W3188869439 isRetracted "false" @default.
- W3188869439 magId "3188869439" @default.
- W3188869439 workType "article" @default.