Matches in SemOpenAlex for { <https://semopenalex.org/work/W3189053302> ?p ?o ?g. }
- W3189053302 endingPage "448" @default.
- W3189053302 startingPage "432" @default.
- W3189053302 abstract "Hypersensitivity reactions (HSRs) to chemotherapy agents can present a serious challenge to treating patients with preferred or first-line therapies. Allergic reactions through an immunologic mechanism have been established for platinum and taxane agents, which are used to treat a wide variety of cancers including gynecologic cancers. Platin HSRs typically occur after multiple cycles of chemotherapy, reflecting the development of drug IgE sensitization, while taxane HSRs often occur on first or second exposure. Despite observed differences between platin and taxane HSRs, drug desensitization has been an effective method to reintroduce both chemotherapeutic agents safely. Skin testing is the primary diagnostic tool used to risk-stratify patients after initial HSRs, with more widespread use for platinum agents than taxanes. Different practices exist around the use of skin testing, drug challenge, and choice of desensitization protocol. Here, we review the epidemiology, mechanism, and clinical presentation of HSRs to platinum and taxane agents, as well as key controversies in their evaluation and management." @default.
- W3189053302 created "2021-08-16" @default.
- W3189053302 creator A5033615608 @default.
- W3189053302 creator A5041260709 @default.
- W3189053302 creator A5063121547 @default.
- W3189053302 creator A5071891127 @default.
- W3189053302 date "2021-08-02" @default.
- W3189053302 modified "2023-10-17" @default.
- W3189053302 title "Hypersensitivity Reactions to Platinum Agents and Taxanes" @default.
- W3189053302 cites W1910585037 @default.
- W3189053302 cites W1933132098 @default.
- W3189053302 cites W1963704593 @default.
- W3189053302 cites W1965734869 @default.
- W3189053302 cites W1966985559 @default.
- W3189053302 cites W1974538967 @default.
- W3189053302 cites W1975525509 @default.
- W3189053302 cites W1982777554 @default.
- W3189053302 cites W1991233593 @default.
- W3189053302 cites W1997917050 @default.
- W3189053302 cites W2008745570 @default.
- W3189053302 cites W2013117769 @default.
- W3189053302 cites W2016793234 @default.
- W3189053302 cites W2036177573 @default.
- W3189053302 cites W2038998118 @default.
- W3189053302 cites W2041155215 @default.
- W3189053302 cites W2051982165 @default.
- W3189053302 cites W2052919388 @default.
- W3189053302 cites W2054844505 @default.
- W3189053302 cites W2065510755 @default.
- W3189053302 cites W2067038726 @default.
- W3189053302 cites W2070957637 @default.
- W3189053302 cites W2073302657 @default.
- W3189053302 cites W2094642620 @default.
- W3189053302 cites W2103346905 @default.
- W3189053302 cites W2108160031 @default.
- W3189053302 cites W2111970355 @default.
- W3189053302 cites W2122435248 @default.
- W3189053302 cites W2123526148 @default.
- W3189053302 cites W2124199693 @default.
- W3189053302 cites W2124205535 @default.
- W3189053302 cites W2131001008 @default.
- W3189053302 cites W2132309212 @default.
- W3189053302 cites W2139057757 @default.
- W3189053302 cites W2150122864 @default.
- W3189053302 cites W2153017356 @default.
- W3189053302 cites W2157551641 @default.
- W3189053302 cites W2162570207 @default.
- W3189053302 cites W2164934025 @default.
- W3189053302 cites W2214575626 @default.
- W3189053302 cites W2277193396 @default.
- W3189053302 cites W2323394841 @default.
- W3189053302 cites W2413885532 @default.
- W3189053302 cites W2518969580 @default.
- W3189053302 cites W2531961325 @default.
- W3189053302 cites W2562654683 @default.
- W3189053302 cites W2605505117 @default.
- W3189053302 cites W2606876201 @default.
- W3189053302 cites W2744362075 @default.
- W3189053302 cites W2747427627 @default.
- W3189053302 cites W2762777651 @default.
- W3189053302 cites W2769073740 @default.
- W3189053302 cites W2784036091 @default.
- W3189053302 cites W2791685657 @default.
- W3189053302 cites W2795382146 @default.
- W3189053302 cites W2801053241 @default.
- W3189053302 cites W2885196309 @default.
- W3189053302 cites W2886976117 @default.
- W3189053302 cites W2886991706 @default.
- W3189053302 cites W2895212220 @default.
- W3189053302 cites W2902413552 @default.
- W3189053302 cites W2913149856 @default.
- W3189053302 cites W2979350674 @default.
- W3189053302 cites W2989188350 @default.
- W3189053302 cites W2997886131 @default.
- W3189053302 cites W3005098770 @default.
- W3189053302 cites W3007243407 @default.
- W3189053302 cites W3037411872 @default.
- W3189053302 cites W3049338896 @default.
- W3189053302 cites W3092175260 @default.
- W3189053302 cites W3107481662 @default.
- W3189053302 cites W748055283 @default.
- W3189053302 doi "https://doi.org/10.1007/s12016-021-08877-y" @default.
- W3189053302 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34338975" @default.
- W3189053302 hasPublicationYear "2021" @default.
- W3189053302 type Work @default.
- W3189053302 sameAs 3189053302 @default.
- W3189053302 citedByCount "22" @default.
- W3189053302 countsByYear W31890533022021 @default.
- W3189053302 countsByYear W31890533022022 @default.
- W3189053302 countsByYear W31890533022023 @default.
- W3189053302 crossrefType "journal-article" @default.
- W3189053302 hasAuthorship W3189053302A5033615608 @default.
- W3189053302 hasAuthorship W3189053302A5041260709 @default.
- W3189053302 hasAuthorship W3189053302A5063121547 @default.
- W3189053302 hasAuthorship W3189053302A5071891127 @default.
- W3189053302 hasBestOaLocation W31890533021 @default.
- W3189053302 hasConcept C121608353 @default.
- W3189053302 hasConcept C126322002 @default.