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- W3189096253 abstract "Abstract Cancer cells exhibit a unique phenotype of efficiently altered metabolism that encompasses not only the bioenergetic demands of the cell, but also generation of precursors of biosynthetic molecules, along with the induction of homeostatic pathways that support uncontrolled cell growth and proliferation. Mitochondria, the cellular metabolic hubs, play a key role in cancer pathophysiology. We have only started to understand the complex metabolic interplay between the cancer cells and the microenvironment, especially involving the role of mitochondria and their underlying mechanisms that sustain cancer cell growth. In this chapter, we review the studies uncovering the role of mitochondria from the perspective of a normal cell undergoing changes resulting in uncontrolled growth and tumor formation." @default.
- W3189096253 created "2021-08-16" @default.
- W3189096253 creator A5006122006 @default.
- W3189096253 creator A5020587613 @default.
- W3189096253 creator A5026416444 @default.
- W3189096253 date "2021-01-01" @default.
- W3189096253 modified "2023-09-26" @default.
- W3189096253 title "Mitochondrial metabolism and carcinogenesis" @default.
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