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• W3189390510 abstract "Objective findings of brain injury or dysfunction are typically lacking in mild traumatic brain injury (MTBI) despite prolonged post-concussion symptoms in some patients. Thus, there is a need for objective biomarkers of MTBI that reflect altered brain physiology underlying subjective symptoms. We have previously reported increased attention to threat-related stimuli in subjects with MTBI, suggesting a physiological vulnerability to depression. Vulnerability to depression has been linked with relatively greater activity of the right than left frontal cortex reflected in inverse pattern in frontal alpha with greater power on the left than right. We investigated whether patients with previous MTBI show this pattern of frontal activity reflected in more negative frontal alpha asymmetry (FAA) scores. Furthermore, in search for potential biomarkers of MTBI, we created a novel index, emotional modulation of FAA (eFAA) and investigated whether it correlates with subjective symptoms. EEG was recorded while subjects with previous MTBI and controls performed a computer-based reaction time task integrating different cognitive executive functions and containing either threat-related or emotionally neutral visual stimuli. Post-concussion symptoms and depression were assessed using the Rivermead Post-Concussion Symptoms Questionnaire (RPQ) and Beck’s depression inventory (BDI). Task-induced FAA was assessed and eFAA calculated by subtracting FAA in the context of neutral stimuli from FAA in the context of emotional stimuli. The MTBI group showed FAA scores reflecting relatively greater right-sided frontal activity compared to healthy controls. eFAA differentiated the symptomatic MTBI from non-symptomatic MTBI group and from healthy controls. eFAA also correlated with RPQ and BDI scores. In conclusion, FAA pattern previously linked with vulnerability to depression, was observed in patients with previous MTBI. Furthermore, eFAA has potential as a biomarker of altered affective brain functions in MTBI." @default.
• W3189390510 created "2021-08-16" @default.
• W3189390510 creator A5022891972 @default.
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• W3189390510 date "2021-07-20" @default.
• W3189390510 modified "2023-09-25" @default.
• W3189390510 title "Emotional Modulation of Frontal Alpha Asymmetry - a Novel Biomarker of Mild Traumatic Brain Injury" @default.
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• W3189390510 cites W1848182291 @default.
• W3189390510 cites W1965139263 @default.
• W3189390510 cites W1972110985 @default.
• W3189390510 cites W1976024574 @default.
• W3189390510 cites W1984203703 @default.
• W3189390510 cites W1984299063 @default.
• W3189390510 cites W2004506384 @default.
• W3189390510 cites W2008281590 @default.
• W3189390510 cites W2011595299 @default.
• W3189390510 cites W2014413360 @default.
• W3189390510 cites W2018010458 @default.
• W3189390510 cites W2019524683 @default.
• W3189390510 cites W2025751302 @default.
• W3189390510 cites W2030761940 @default.
• W3189390510 cites W2036556238 @default.
• W3189390510 cites W2039643450 @default.
• W3189390510 cites W2051398737 @default.
• W3189390510 cites W2053912118 @default.
• W3189390510 cites W2056565869 @default.
• W3189390510 cites W2058331473 @default.
• W3189390510 cites W2069374832 @default.
• W3189390510 cites W2074332092 @default.
• W3189390510 cites W2084757075 @default.
• W3189390510 cites W2087150616 @default.
• W3189390510 cites W2087393332 @default.
• W3189390510 cites W2090940281 @default.
• W3189390510 cites W2098182568 @default.
• W3189390510 cites W2099076640 @default.
• W3189390510 cites W2099515406 @default.
• W3189390510 cites W2102748276 @default.
• W3189390510 cites W2104142411 @default.
• W3189390510 cites W2108029018 @default.
• W3189390510 cites W2109032638 @default.
• W3189390510 cites W2110004174 @default.
• W3189390510 cites W2111279030 @default.
• W3189390510 cites W2115433360 @default.
• W3189390510 cites W2121533477 @default.
• W3189390510 cites W2123407155 @default.
• W3189390510 cites W2125838454 @default.
• W3189390510 cites W2129285116 @default.
• W3189390510 cites W2130911295 @default.
• W3189390510 cites W2132435594 @default.
• W3189390510 cites W2133214170 @default.
• W3189390510 cites W2135629133 @default.
• W3189390510 cites W2135755174 @default.
• W3189390510 cites W2141854118 @default.
• W3189390510 cites W2152676381 @default.
• W3189390510 cites W2164136348 @default.
• W3189390510 cites W2167575933 @default.
• W3189390510 cites W2168768134 @default.
• W3189390510 cites W2182099068 @default.
• W3189390510 cites W2188287479 @default.
• W3189390510 cites W2332249312 @default.
• W3189390510 cites W2341273958 @default.
• W3189390510 cites W2344280487 @default.
• W3189390510 cites W2514213608 @default.
• W3189390510 cites W2524766497 @default.
• W3189390510 cites W2528886567 @default.
• W3189390510 cites W2588954859 @default.
• W3189390510 cites W2734653885 @default.
• W3189390510 cites W2742646820 @default.
• W3189390510 cites W2755125360 @default.
• W3189390510 cites W2765788989 @default.
• W3189390510 cites W2775384618 @default.
• W3189390510 cites W2799483411 @default.
• W3189390510 cites W2801154442 @default.
• W3189390510 cites W2842014277 @default.
• W3189390510 cites W2887951033 @default.
• W3189390510 cites W2899167557 @default.
• W3189390510 cites W2904967164 @default.
• W3189390510 cites W2905363351 @default.
• W3189390510 cites W2912370667 @default.
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• W3189390510 doi "https://doi.org/10.3389/fnhum.2021.699947" @default.
• W3189390510 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8329358" @default.
• W3189390510 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34354578" @default.
• W3189390510 hasPublicationYear "2021" @default.
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