FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3189391161> ?p ?o ?g. }

• W3189391161 abstract "There are limited data on emergence of allergic sensitization (or atopy) during childhood in tropical regions.We followed a birth cohort of 2404 newborns to 8 years in tropical Ecuador and collected: risk factor data by maternal questionnaires periodically from birth; atopy was measured by skin prick test reactivity (SPT) to aeroallergens in parents, and aeroallergens and food allergens in children at 2, 3, 5, and 8 years; and stool samples for soil-transmitted helminths (STH) from children periodically to 8 years and from parents and household members at the time of recruitment of cohort children. Data on risk factors were measured either at birth or repeatedly (time-varying) from birth to 8 years. Longitudinal repeated-measures analyses were done using generalized estimating equations to estimate an the age-dependent risk of positive SPT (SPT+) to any allergen or mite during early childhood to school age.SPT+ to any allergen was present in 29.0% of fathers and 24.8% of mothers, and in cohort children increased with age, initially to mite but later to cockroach, reaching 14.8% to any allergen (10.7% mite and 5.3% cockroach) at 8 years. Maternal SPT+, particularly presence of polysensitization (OR 2.04, 95% CI 1.49-2.77) significantly increased the risk of SPT+ during childhood, while household overcrowding at birth decreased the risk (OR 0.84, 95% CI 0.72-0.98). For mite sensitization, maternal polysensitization increased (OR 2.14, 95% CI 1.40-3.27) but rural residence (OR 0.69, 95% CI 0.50-0.94) and birth order (3rd -4th vs. 1st - 2nd: OR 0.71, 95% CI 0.52-0.98) decreased the risk. Time-varying exposures to agricultural activities (OR 0.77, 95% CI 0.60-0.98) and STH parasites (OR 0.70, 95% CI 0.64-0.91) during childhood decreased while anthelmintics increased the childhood risk (OR 1.47, 95% CI 1.05-2.05) of mite sensitization.Our data showed the emergence of allergic sensitization, primarily to mite and cockroach allergens, during childhood in tropical Ecuador. A role for both antenatal and postnatal factors acting as potential determinants of SPT+ emergence was observed." @default.
• W3189391161 created "2021-08-16" @default.
• W3189391161 creator A5013693596 @default.
• W3189391161 creator A5023211986 @default.
• W3189391161 creator A5042413273 @default.
• W3189391161 creator A5059471407 @default.
• W3189391161 creator A5072938610 @default.
• W3189391161 creator A5086609484 @default.
• W3189391161 date "2021-08-05" @default.
• W3189391161 modified "2023-10-16" @default.
• W3189391161 title "Patterns of Allergic Sensitization and Factors Associated With Emergence of Sensitization in the Rural Tropics Early in the Life Course: Findings of an Ecuadorian Birth Cohort" @default.
• W3189391161 cites W1531439921 @default.
• W3189391161 cites W1688786347 @default.
• W3189391161 cites W1944247777 @default.
• W3189391161 cites W1965191229 @default.
• W3189391161 cites W1971626645 @default.
• W3189391161 cites W1973470298 @default.
• W3189391161 cites W1978213037 @default.
• W3189391161 cites W1988285838 @default.
• W3189391161 cites W1993745762 @default.
• W3189391161 cites W1997489678 @default.
• W3189391161 cites W2010436984 @default.
• W3189391161 cites W2017581706 @default.
• W3189391161 cites W2021312126 @default.
• W3189391161 cites W2040953888 @default.
• W3189391161 cites W2058233929 @default.
• W3189391161 cites W2076357708 @default.
• W3189391161 cites W2076539791 @default.
• W3189391161 cites W2088361246 @default.
• W3189391161 cites W2088751659 @default.
• W3189391161 cites W2100205243 @default.
• W3189391161 cites W2100706982 @default.
• W3189391161 cites W2101962380 @default.
• W3189391161 cites W2103318681 @default.
• W3189391161 cites W2108230171 @default.
• W3189391161 cites W2109414577 @default.
• W3189391161 cites W2110528442 @default.
• W3189391161 cites W2110776215 @default.
• W3189391161 cites W2113107388 @default.
• W3189391161 cites W2117845549 @default.
• W3189391161 cites W2119158574 @default.
• W3189391161 cites W2124569327 @default.
• W3189391161 cites W2135645244 @default.
• W3189391161 cites W2144267046 @default.
• W3189391161 cites W2153603279 @default.
• W3189391161 cites W2154364436 @default.
• W3189391161 cites W2155605596 @default.
• W3189391161 cites W2158211513 @default.
• W3189391161 cites W2165543736 @default.
• W3189391161 cites W2187303021 @default.
• W3189391161 cites W2442307593 @default.
• W3189391161 cites W2466995319 @default.
• W3189391161 cites W2470895291 @default.
• W3189391161 cites W2527611349 @default.
• W3189391161 cites W2598332240 @default.
• W3189391161 cites W2602088680 @default.
• W3189391161 cites W2609459487 @default.
• W3189391161 cites W2733928499 @default.
• W3189391161 cites W2753887227 @default.
• W3189391161 cites W2757874120 @default.
• W3189391161 cites W2768801238 @default.
• W3189391161 cites W2802776851 @default.
• W3189391161 cites W2901887816 @default.
• W3189391161 cites W2968310200 @default.
• W3189391161 cites W2972206552 @default.
• W3189391161 cites W2995504166 @default.
• W3189391161 cites W3001343540 @default.
• W3189391161 cites W3041728363 @default.
• W3189391161 cites W3088769220 @default.
• W3189391161 cites W3104010835 @default.
• W3189391161 cites W3132027863 @default.
• W3189391161 cites W3138648421 @default.
• W3189391161 cites W4249564242 @default.
• W3189391161 doi "https://doi.org/10.3389/falgy.2021.687073" @default.
• W3189391161 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34888545" @default.
• W3189391161 hasPublicationYear "2021" @default.
• W3189391161 type Work @default.
• W3189391161 sameAs 3189391161 @default.
• W3189391161 citedByCount "4" @default.
• W3189391161 countsByYear W31893911612022 @default.
• W3189391161 countsByYear W31893911612023 @default.
• W3189391161 crossrefType "journal-article" @default.
• W3189391161 hasAuthorship W3189391161A5013693596 @default.
• W3189391161 hasAuthorship W3189391161A5023211986 @default.
• W3189391161 hasAuthorship W3189391161A5042413273 @default.
• W3189391161 hasAuthorship W3189391161A5059471407 @default.
• W3189391161 hasAuthorship W3189391161A5072938610 @default.
• W3189391161 hasAuthorship W3189391161A5086609484 @default.
• W3189391161 hasBestOaLocation W31893911611 @default.
• W3189391161 hasConcept C126322002 @default.
• W3189391161 hasConcept C144024400 @default.
• W3189391161 hasConcept C149923435 @default.
• W3189391161 hasConcept C187212893 @default.
• W3189391161 hasConcept C18903297 @default.
• W3189391161 hasConcept C201903717 @default.
• W3189391161 hasConcept C203014093 @default.
• W3189391161 hasConcept C207480886 @default.
• W3189391161 hasConcept C2776217527 @default.
• W3189391161 hasConcept C2777697326 @default.
• W3189391161 hasConcept C2778166374 @default.

• next