FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3189407711> ?p ?o ?g. }

• W3189407711 abstract "The prevalence of chronic kidney disease (CKD) in the United States is 13% of the general population. Among those with CKD, diabetic nephropathy is the leading cause of end-stage renal disease. This is a retrospective study examining the effect of long-term use of dipeptidyl peptidase-4 (DPP-4) inhibitors on all-cause mortality and progression of renal disease in the veteran population.Data was extracted using the Veterans Administration Informatics and Computing Infrastructure. A large cohort of veterans diagnosed with type 2 diabetes mellitus were used to identify patients on DPP-4 inhibitors and without DPP-4 inhibitors. Groups were compared to determine the effect of DPP-4 inhibitors on the progression of CKD and all-cause mortality. Data were analyzed using SAS.Subjects in the treatment group (n = 40 558) had baseline variables (age, body mass index, race) similar to the control group (n = 40 558). Diabetes control improved in the treatment group (HgbA1c, 8.3% [67 mmol/mol] to 7.8% [62 mmol/mol]; P < .001) but not in the control group (HgbA1c, 7.4% [57 mmol/mol] to 7.3% [56 mmol/mol]). New diagnoses of heart failure and coronary artery bypass grafts were clinically significant (odds ratios = 0.66 and 0.52). No change in progression of CKD was seen in either group. All-cause mortality was reduced by 59%.We conclude that DPP-4 inhibitors are associated with a significant reduction in all-cause mortality independent of glucose control, albeit with no clear cause, including obtainable cardiovascular outcomes. Our data is consistent with prior trials in that DPP-4 inhibitors did not show a significant change in serum creatinine or microalbuminuria." @default.
• W3189407711 created "2021-08-16" @default.
• W3189407711 creator A5000601377 @default.
• W3189407711 creator A5005901108 @default.
• W3189407711 creator A5010160955 @default.
• W3189407711 creator A5023346326 @default.
• W3189407711 creator A5029636462 @default.
• W3189407711 creator A5029842168 @default.
• W3189407711 creator A5052922471 @default.
• W3189407711 creator A5059447019 @default.
• W3189407711 creator A5088931891 @default.
• W3189407711 date "2021-08-01" @default.
• W3189407711 modified "2023-10-15" @default.
• W3189407711 title "Decreased Mortality After Long-Term Treatment With Dipeptidyl Peptidase-4 Inhibitors: A Retrospective Study of U.S. Veterans With Type 2 Diabetes" @default.
• W3189407711 cites W1964884427 @default.
• W3189407711 cites W1967096313 @default.
• W3189407711 cites W1967458701 @default.
• W3189407711 cites W1992519606 @default.
• W3189407711 cites W2013527141 @default.
• W3189407711 cites W2025115974 @default.
• W3189407711 cites W2043804599 @default.
• W3189407711 cites W2045516356 @default.
• W3189407711 cites W2050781927 @default.
• W3189407711 cites W2053703172 @default.
• W3189407711 cites W2099683917 @default.
• W3189407711 cites W2101457616 @default.
• W3189407711 cites W2114598208 @default.
• W3189407711 cites W2121633948 @default.
• W3189407711 cites W2142226770 @default.
• W3189407711 cites W2156900346 @default.
• W3189407711 cites W2222285657 @default.
• W3189407711 cites W2345478245 @default.
• W3189407711 cites W2417331731 @default.
• W3189407711 cites W2530634871 @default.
• W3189407711 cites W2534221266 @default.
• W3189407711 cites W2639738157 @default.
• W3189407711 cites W2750733474 @default.
• W3189407711 cites W2771786039 @default.
• W3189407711 cites W2788483598 @default.
• W3189407711 cites W2804712568 @default.
• W3189407711 cites W2886078935 @default.
• W3189407711 cites W2900149048 @default.
• W3189407711 cites W2974098728 @default.
• W3189407711 cites W3013421587 @default.
• W3189407711 doi "https://doi.org/10.1016/j.eprac.2021.07.017" @default.
• W3189407711 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34371197" @default.
• W3189407711 hasPublicationYear "2021" @default.
• W3189407711 type Work @default.
• W3189407711 sameAs 3189407711 @default.
• W3189407711 citedByCount "0" @default.
• W3189407711 crossrefType "journal-article" @default.
• W3189407711 hasAuthorship W3189407711A5000601377 @default.
• W3189407711 hasAuthorship W3189407711A5005901108 @default.
• W3189407711 hasAuthorship W3189407711A5010160955 @default.
• W3189407711 hasAuthorship W3189407711A5023346326 @default.
• W3189407711 hasAuthorship W3189407711A5029636462 @default.
• W3189407711 hasAuthorship W3189407711A5029842168 @default.
• W3189407711 hasAuthorship W3189407711A5052922471 @default.
• W3189407711 hasAuthorship W3189407711A5059447019 @default.
• W3189407711 hasAuthorship W3189407711A5088931891 @default.
• W3189407711 hasBestOaLocation W31894077111 @default.
• W3189407711 hasConcept C126322002 @default.
• W3189407711 hasConcept C134018914 @default.
• W3189407711 hasConcept C156957248 @default.
• W3189407711 hasConcept C167135981 @default.
• W3189407711 hasConcept C2775969662 @default.
• W3189407711 hasConcept C2777180221 @default.
• W3189407711 hasConcept C2778213512 @default.
• W3189407711 hasConcept C2778653478 @default.
• W3189407711 hasConcept C2778763485 @default.
• W3189407711 hasConcept C2779922275 @default.
• W3189407711 hasConcept C2781184683 @default.
• W3189407711 hasConcept C2908647359 @default.
• W3189407711 hasConcept C555293320 @default.
• W3189407711 hasConcept C71924100 @default.
• W3189407711 hasConcept C90924648 @default.
• W3189407711 hasConcept C99454951 @default.
• W3189407711 hasConceptScore W3189407711C126322002 @default.
• W3189407711 hasConceptScore W3189407711C134018914 @default.
• W3189407711 hasConceptScore W3189407711C156957248 @default.
• W3189407711 hasConceptScore W3189407711C167135981 @default.
• W3189407711 hasConceptScore W3189407711C2775969662 @default.
• W3189407711 hasConceptScore W3189407711C2777180221 @default.
• W3189407711 hasConceptScore W3189407711C2778213512 @default.
• W3189407711 hasConceptScore W3189407711C2778653478 @default.
• W3189407711 hasConceptScore W3189407711C2778763485 @default.
• W3189407711 hasConceptScore W3189407711C2779922275 @default.
• W3189407711 hasConceptScore W3189407711C2781184683 @default.
• W3189407711 hasConceptScore W3189407711C2908647359 @default.
• W3189407711 hasConceptScore W3189407711C555293320 @default.
• W3189407711 hasConceptScore W3189407711C71924100 @default.
• W3189407711 hasConceptScore W3189407711C90924648 @default.
• W3189407711 hasConceptScore W3189407711C99454951 @default.
• W3189407711 hasLocation W31894077111 @default.
• W3189407711 hasLocation W31894077112 @default.
• W3189407711 hasOpenAccess W3189407711 @default.
• W3189407711 hasPrimaryLocation W31894077111 @default.
• W3189407711 hasRelatedWork W14643057 @default.
• W3189407711 hasRelatedWork W15105161 @default.
• W3189407711 hasRelatedWork W17661181 @default.

• next