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- W3189698384 abstract "'Muscle-on-Chip' technologies have been developed to serve as physiologically relevant animal substitutes for in-vitro screening of drugs and study of myogenesis. The formation of 3D suspended myo-bundles within a contractable hydrogel in 'Muscle-on-Chip' devices has been well-established thus far. However, very limited studies have elucidated (i) The effect of physiological shear stresses and (ii) The mechanical properties of the 3D hydrogel microenvironment in myo-bundle formation and their subsequent myogenesis. As such, we have developed a perfusable 'Muscle-on-Chip' device which will enable us to study the effect of these dynamic stimuli on myo-bundle formation and maturation." @default.
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- W3189698384 date "2019-01-01" @default.
- W3189698384 modified "2023-09-27" @default.
- W3189698384 title "Muscle on chip with a mechanically tunable 3D microenvironment" @default.
- W3189698384 hasPublicationYear "2019" @default.
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