FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3189968751> ?p ?o ?g. }

• W3189968751 abstract "Background: Neutrophil-to-lymphocyte ratio (NLR) is an indicator of poor prognosis in acute ischemic stroke (AIS), but associations between NLR with stroke severity and prognosis of intracranial atherosclerotic stenosis (ICAS)-related ischemic events have not been well-elucidated; therefore, we aimed to evaluate whether admission NLR levels correlate with the early stroke severity and short-term functional prognosis in patients with symptomatic intracranial atherosclerotic stenosis (sICAS). Methods: This retrospective study enrolled 899 consecutive patients with AIS attributed to ICAS at Xiangya Hospital stroke center between May 2016 and September 2020. The initial stroke severity was rated by the admission National Institutes of Health Stroke Scale (NIHSS) scores, and the short-term prognosis was evaluated using the 14-day modified Rankin Scale (mRS) scores after stroke onset. A severe stroke was defined as NIHSS &gt;8; an unfavorable functional outcome was defined as mRS scores of 3–6. Admission NLR was determined based on circulating neutrophil and lymphocyte counts. Results: The median admission NLR of all patients was 2.80 [interquartile range (IQR), 2.00–4.00]. In univariate analysis, admission NLR was significantly elevated in patients with severe stroke and poor short-term prognosis. After multivariate adjustment, admission NLR levels were significantly correlated with severe stroke [odds ratio (OR), 1.132; 95% confidence interval (95% CI), 1.038–1.234; P = 0.005] and unfavorable short-term prognosis (OR, 1.102; 95% CI, 1.017–1.195; P = 0.018) in Model 1. In Model 2, the highest NLR tertile (≥3.533) remained an independent predictor of severe stroke (OR, 2.736; 95% CI, 1.590–4.708; P &lt; 0.001) and unfavorable functional outcome (OR, 2.165; 95% CI, 1.416–3.311; P &lt; 0.001) compared with the lowest NLR tertile (&lt;2.231). The receiver operating characteristic (ROC) curves showed the predictability of NLR regarding the stroke severity [area under the curve (AUC), 0.659; 95% CI, 0.615–0.703; P &lt; 0.001] and short-term prognosis (AUC, 0.613; 95% CI, 0.575–0.650; P &lt; 0.001). The nomograms were constructed to create the predictive models of the severity and short-term outcome of sICAS. Conclusions: Elevated admission NLR levels were independently associated with the initial stroke severity and could be an early predictor of severity and poor short-term prognosis in AIS patients with ICAS, which might help us identify a target group timely for preventive therapies." @default.
• W3189968751 created "2021-08-16" @default.
• W3189968751 creator A5012513461 @default.
• W3189968751 creator A5013680342 @default.
• W3189968751 creator A5029300665 @default.
• W3189968751 creator A5030129255 @default.
• W3189968751 creator A5036145381 @default.
• W3189968751 creator A5038894100 @default.
• W3189968751 creator A5043161271 @default.
• W3189968751 creator A5046425378 @default.
• W3189968751 creator A5056078581 @default.
• W3189968751 creator A5071550953 @default.
• W3189968751 creator A5084280955 @default.
• W3189968751 creator A5087657305 @default.
• W3189968751 creator A5089197766 @default.
• W3189968751 date "2021-07-29" @default.
• W3189968751 modified "2023-10-18" @default.
• W3189968751 title "Neutrophil-to-Lymphocyte Ratio as a Predictive Biomarker for Stroke Severity and Short-Term Prognosis in Acute Ischemic Stroke With Intracranial Atherosclerotic Stenosis" @default.
• W3189968751 cites W1644190097 @default.
• W3189968751 cites W1925096404 @default.
• W3189968751 cites W1970328528 @default.
• W3189968751 cites W1985759654 @default.
• W3189968751 cites W1987177757 @default.
• W3189968751 cites W2007708972 @default.
• W3189968751 cites W2024661673 @default.
• W3189968751 cites W2042325978 @default.
• W3189968751 cites W2066908615 @default.
• W3189968751 cites W2074897979 @default.
• W3189968751 cites W2077720998 @default.
• W3189968751 cites W2079581808 @default.
• W3189968751 cites W2084049757 @default.
• W3189968751 cites W2093099046 @default.
• W3189968751 cites W2112489310 @default.
• W3189968751 cites W2118855104 @default.
• W3189968751 cites W2126625630 @default.
• W3189968751 cites W2132357532 @default.
• W3189968751 cites W2144647124 @default.
• W3189968751 cites W2154871450 @default.
• W3189968751 cites W2159103481 @default.
• W3189968751 cites W2324841714 @default.
• W3189968751 cites W2509686368 @default.
• W3189968751 cites W2560013748 @default.
• W3189968751 cites W2586885926 @default.
• W3189968751 cites W2587867925 @default.
• W3189968751 cites W2601611244 @default.
• W3189968751 cites W2747335908 @default.
• W3189968751 cites W2782524791 @default.
• W3189968751 cites W2791126679 @default.
• W3189968751 cites W2793386589 @default.
• W3189968751 cites W2810187098 @default.
• W3189968751 cites W2840437223 @default.
• W3189968751 cites W2893121920 @default.
• W3189968751 cites W2901854445 @default.
• W3189968751 cites W2970522453 @default.
• W3189968751 cites W2980372446 @default.
• W3189968751 cites W3003299879 @default.
• W3189968751 cites W3005364124 @default.
• W3189968751 cites W3007475635 @default.
• W3189968751 cites W3026093678 @default.
• W3189968751 cites W3083785037 @default.
• W3189968751 cites W3126773274 @default.
• W3189968751 cites W3127759393 @default.
• W3189968751 doi "https://doi.org/10.3389/fneur.2021.705949" @default.
• W3189968751 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8360230" @default.
• W3189968751 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34393983" @default.
• W3189968751 hasPublicationYear "2021" @default.
• W3189968751 type Work @default.
• W3189968751 sameAs 3189968751 @default.
• W3189968751 citedByCount "9" @default.
• W3189968751 countsByYear W31899687512021 @default.
• W3189968751 countsByYear W31899687512022 @default.
• W3189968751 countsByYear W31899687512023 @default.
• W3189968751 crossrefType "journal-article" @default.
• W3189968751 hasAuthorship W3189968751A5012513461 @default.
• W3189968751 hasAuthorship W3189968751A5013680342 @default.
• W3189968751 hasAuthorship W3189968751A5029300665 @default.
• W3189968751 hasAuthorship W3189968751A5030129255 @default.
• W3189968751 hasAuthorship W3189968751A5036145381 @default.
• W3189968751 hasAuthorship W3189968751A5038894100 @default.
• W3189968751 hasAuthorship W3189968751A5043161271 @default.
• W3189968751 hasAuthorship W3189968751A5046425378 @default.
• W3189968751 hasAuthorship W3189968751A5056078581 @default.
• W3189968751 hasAuthorship W3189968751A5071550953 @default.
• W3189968751 hasAuthorship W3189968751A5084280955 @default.
• W3189968751 hasAuthorship W3189968751A5087657305 @default.
• W3189968751 hasAuthorship W3189968751A5089197766 @default.
• W3189968751 hasBestOaLocation W31899687511 @default.
• W3189968751 hasConcept C119060515 @default.
• W3189968751 hasConcept C126322002 @default.
• W3189968751 hasConcept C127413603 @default.
• W3189968751 hasConcept C144301174 @default.
• W3189968751 hasConcept C156957248 @default.
• W3189968751 hasConcept C164705383 @default.
• W3189968751 hasConcept C2777761686 @default.
• W3189968751 hasConcept C2778963024 @default.
• W3189968751 hasConcept C2780007028 @default.
• W3189968751 hasConcept C2780645631 @default.
• W3189968751 hasConcept C2780931571 @default.
• W3189968751 hasConcept C3020199598 @default.
• W3189968751 hasConcept C38180746 @default.

• next