Matches in SemOpenAlex for { <https://semopenalex.org/work/W3190810637> ?p ?o ?g. }
- W3190810637 endingPage "528" @default.
- W3190810637 startingPage "517" @default.
- W3190810637 abstract "Despite the apparent complexity of the molecular genetic underpinnings of myeloid neoplasms, most myeloid mutational profiles can be understood within a simple framework. Somatic mutations accumulate in hematopoietic stem cells with aging and toxic insults, termed clonal hematopoiesis. These old stem cells mutations, predominantly in the epigenetic and RNA spliceosome pathways, act as founding driver mutations leading to a clonal myeloid neoplasm when sufficient in number and clone size. Subsequent mutations can create the genetic flavor of the myeloid neoplasm (backseat drivers) due to their enrichment in certain entities or act as progression events (aggressive drivers) during clonal evolution." @default.
- W3190810637 created "2021-08-16" @default.
- W3190810637 creator A5026268460 @default.
- W3190810637 creator A5059770942 @default.
- W3190810637 date "2021-09-01" @default.
- W3190810637 modified "2023-10-14" @default.
- W3190810637 title "Molecular Pathology of Myeloid Neoplasms" @default.
- W3190810637 cites W1255676896 @default.
- W3190810637 cites W1493182913 @default.
- W3190810637 cites W1920829940 @default.
- W3190810637 cites W1985823023 @default.
- W3190810637 cites W1987628847 @default.
- W3190810637 cites W1992826811 @default.
- W3190810637 cites W2009650262 @default.
- W3190810637 cites W2012753533 @default.
- W3190810637 cites W2026134786 @default.
- W3190810637 cites W2030716854 @default.
- W3190810637 cites W2038795176 @default.
- W3190810637 cites W2073440691 @default.
- W3190810637 cites W2086704257 @default.
- W3190810637 cites W2090885521 @default.
- W3190810637 cites W2105248187 @default.
- W3190810637 cites W2107027906 @default.
- W3190810637 cites W2126032044 @default.
- W3190810637 cites W2126816979 @default.
- W3190810637 cites W2138122783 @default.
- W3190810637 cites W2139464974 @default.
- W3190810637 cites W2146142395 @default.
- W3190810637 cites W2149858388 @default.
- W3190810637 cites W2162079601 @default.
- W3190810637 cites W2187320767 @default.
- W3190810637 cites W2326726820 @default.
- W3190810637 cites W2416023646 @default.
- W3190810637 cites W2419140434 @default.
- W3190810637 cites W2558446569 @default.
- W3190810637 cites W2559537906 @default.
- W3190810637 cites W2565781760 @default.
- W3190810637 cites W2574119868 @default.
- W3190810637 cites W2587066646 @default.
- W3190810637 cites W2599630893 @default.
- W3190810637 cites W2606218280 @default.
- W3190810637 cites W2612571615 @default.
- W3190810637 cites W2612643019 @default.
- W3190810637 cites W2628145035 @default.
- W3190810637 cites W2663243670 @default.
- W3190810637 cites W2767347576 @default.
- W3190810637 cites W2794480810 @default.
- W3190810637 cites W2843925039 @default.
- W3190810637 cites W2888686509 @default.
- W3190810637 cites W2891092031 @default.
- W3190810637 cites W2896385413 @default.
- W3190810637 cites W2903920099 @default.
- W3190810637 cites W2922491838 @default.
- W3190810637 cites W2995223139 @default.
- W3190810637 cites W3011073849 @default.
- W3190810637 cites W3046671820 @default.
- W3190810637 cites W3086638260 @default.
- W3190810637 cites W3093370683 @default.
- W3190810637 cites W3093490071 @default.
- W3190810637 cites W3104244972 @default.
- W3190810637 cites W3119440663 @default.
- W3190810637 cites W3132068389 @default.
- W3190810637 cites W4234712695 @default.
- W3190810637 doi "https://doi.org/10.1016/j.path.2021.05.013" @default.
- W3190810637 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34373100" @default.
- W3190810637 hasPublicationYear "2021" @default.
- W3190810637 type Work @default.
- W3190810637 sameAs 3190810637 @default.
- W3190810637 citedByCount "2" @default.
- W3190810637 countsByYear W31908106372023 @default.
- W3190810637 crossrefType "journal-article" @default.
- W3190810637 hasAuthorship W3190810637A5026268460 @default.
- W3190810637 hasAuthorship W3190810637A5059770942 @default.
- W3190810637 hasConcept C104317684 @default.
- W3190810637 hasConcept C109159458 @default.
- W3190810637 hasConcept C113968399 @default.
- W3190810637 hasConcept C134305767 @default.
- W3190810637 hasConcept C203014093 @default.
- W3190810637 hasConcept C2778729363 @default.
- W3190810637 hasConcept C2779282312 @default.
- W3190810637 hasConcept C2780007613 @default.
- W3190810637 hasConcept C2780076729 @default.
- W3190810637 hasConcept C2780635560 @default.
- W3190810637 hasConcept C2781107747 @default.
- W3190810637 hasConcept C28328180 @default.
- W3190810637 hasConcept C40000846 @default.
- W3190810637 hasConcept C41091548 @default.
- W3190810637 hasConcept C501734568 @default.
- W3190810637 hasConcept C502942594 @default.
- W3190810637 hasConcept C54355233 @default.
- W3190810637 hasConcept C54458228 @default.
- W3190810637 hasConcept C67705224 @default.
- W3190810637 hasConcept C81089528 @default.
- W3190810637 hasConcept C86803240 @default.
- W3190810637 hasConceptScore W3190810637C104317684 @default.
- W3190810637 hasConceptScore W3190810637C109159458 @default.
- W3190810637 hasConceptScore W3190810637C113968399 @default.
- W3190810637 hasConceptScore W3190810637C134305767 @default.