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- W3191301926 abstract "Psychotic experiences (PE) are forms of hallucinations and delusions neither reaching the intensity and functional impairment required to be regarded as full psychotic symptoms nor a psychotic disorder. Here we investigated the ability to predict PE using multiple models (regressions, mediation and moderation) using polygenic risk score for psychotic experiences (PE-PRS), polygenic risk score for schizophrenia (SCZ-PRS), and polyenvironmental risk score (PERS) in youth from a Brazilian sample. The scores were not able to predict outcome, either when both scores were combined (PERS + PE-PRS and PERS + SCZ-PRS) or separately. Our results show that there is no association between PE and PRS or PERS among adolescents in our Brazilian sample. The lack of association may be a result of the absence of better representativeness regarding genetic and environmental factors of our population." @default.
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- W3191301926 date "2021-10-01" @default.
- W3191301926 modified "2023-10-18" @default.
- W3191301926 title "Polyenvironmental and polygenic risk scores and the emergence of psychotic experiences in adolescents" @default.
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- W3191301926 doi "https://doi.org/10.1016/j.jpsychires.2021.07.057" @default.
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