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• W3191407351 startingPage "112349" @default.
• W3191407351 abstract "Concise, low-cost preparation of titanium alloy implants with high cell proliferation and osteogenic differentiation is urgently needed. Nanosecond laser ablation of titanium alloy has the advantages of short processing time, less pollution, and non-contact. In this research, we adopt a nanosecond UV laser to process the closed groove and cross groove titanium alloys with length to width ratio of 1:1, 2.5:1, 4:1, and 6:1. The surface morphology, surface roughness, phase, element distribution, surface chemistry, and wettability were characterized. The effect of the patterned surface's properties on the adhesion, proliferation, and osteogenic differentiation of stem cells was studied. The results show the laser-ablated lattice structure's surface energy can increase rapidly in the natural environment. The cell adhesion of stem cells on a lattice structure with low roughness and high surface energy is optimal. The element concentration at the ablated edges is higher than at the bottom under Marangoni and surface tension. Stem cells preferentially adhere to the ablated edges with high roughness, element concentration, and hardness. Cell differentiation is chiefly affected by patterning structure. On the surface of the boss structure with a length to width ratio of 2.5:1, the proportion of cell length to diameter is about 2.5, and the cell area is greater. The osteogenic differentiation of cells is the highest on the surface. • Laser ablated edges have high roughness, element concentration, and hardness. • Stem cells preferentially adhere to the edge of laser ablation. • Titanium alloy ablated by nanosecond laser has high surface free energy. • On the surface of high surface energy, low roughness is beneficial to cell adhesion. • The pattern structure affects the morphology and differentiation of stem cells." @default.
• W3191407351 created "2021-08-16" @default.
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• W3191407351 date "2021-09-01" @default.
• W3191407351 modified "2023-10-18" @default.
• W3191407351 title "Study on the effect of surface characteristics of short-pulse laser patterned titanium alloy on cell proliferation and osteogenic differentiation" @default.
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• W3191407351 doi "https://doi.org/10.1016/j.msec.2021.112349" @default.
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