FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3191537411> ?p ?o ?g. }

• W3191537411 endingPage "4493" @default.
• W3191537411 startingPage "4483" @default.
• W3191537411 abstract "The traditional silicate bioactive glasses exhibit poor thermal processability, which inhibits fiber drawing or sintering into scaffolds. The composition of the silicate glasses has been modified to enable hot processing. However, the hot forming ability is generally at the expense of bioactivity. Metaphosphate glasses, on the other hand, possess excellent thermal processability, congruent dissolution, and a tailorable degradation rate. However, due to the layer-by-layer dissolution mechanism, cells do not attach to the material surface. Furthermore, the congruent dissolution leads to a low density of OH groups forming on the glass surface, limiting the adsorption of proteins. It is well regarded that the initial step of protein adsorption is critical as the cells interact with this protein layer, rather than the biomaterial itself. In this paper, we explore the possibility of improving protein adsorption on the surface of phosphate glasses through a variety of surface treatments, such as washing the glass surface in acidic (pH 5), neutral, and basic (pH 9) buffer solutions followed or not by a treatment with (3-aminopropyl)triethoxysilane (APTS). The impact of these surface treatments on the surface chemistry (contact angle, ζ-potential) and glass structure (FTIR) was assessed. In this manuscript, we demonstrate that understanding of the material surface chemistry enables to selectively improve the adsorption of albumin and fibronectin (used as model proteins). Furthermore, in this study, well-known silicate bioactive glasses (i.e., S53P4 and 13-93) were used as controls. While surface treatments clearly improved proteins adsorption on the surface of both silicate and phosphate glasses, it is of interest to note that protein adsorption on phosphate glasses was drastically improved to reach similar protein grafting ability to the silicate bioactive glasses. Overall, this study demonstrates that the limited cell/phosphate glass biological response can easily be overcome through deep understanding and control of the glass surface chemistry." @default.
• W3191537411 created "2021-08-16" @default.
• W3191537411 creator A5010053080 @default.
• W3191537411 creator A5011435536 @default.
• W3191537411 creator A5020199782 @default.
• W3191537411 creator A5027738338 @default.
• W3191537411 creator A5037038554 @default.
• W3191537411 creator A5040628945 @default.
• W3191537411 creator A5044554319 @default.
• W3191537411 creator A5060384406 @default.
• W3191537411 creator A5077269808 @default.
• W3191537411 creator A5077756071 @default.
• W3191537411 date "2021-08-12" @default.
• W3191537411 modified "2023-10-18" @default.
• W3191537411 title "Surface Modification of Bioresorbable Phosphate Glasses for Controlled Protein Adsorption" @default.
• W3191537411 cites W1536028936 @default.
• W3191537411 cites W1593789477 @default.
• W3191537411 cites W1964200863 @default.
• W3191537411 cites W1964713733 @default.
• W3191537411 cites W1971739349 @default.
• W3191537411 cites W1976516525 @default.
• W3191537411 cites W1982090991 @default.
• W3191537411 cites W1987683339 @default.
• W3191537411 cites W1988298551 @default.
• W3191537411 cites W1991110760 @default.
• W3191537411 cites W1991989443 @default.
• W3191537411 cites W1992063550 @default.
• W3191537411 cites W1995063875 @default.
• W3191537411 cites W1999811722 @default.
• W3191537411 cites W2000322294 @default.
• W3191537411 cites W2003099669 @default.
• W3191537411 cites W2003748808 @default.
• W3191537411 cites W2011655214 @default.
• W3191537411 cites W2012012189 @default.
• W3191537411 cites W2012542160 @default.
• W3191537411 cites W2015209658 @default.
• W3191537411 cites W2015236182 @default.
• W3191537411 cites W2020389418 @default.
• W3191537411 cites W2040202961 @default.
• W3191537411 cites W2040468790 @default.
• W3191537411 cites W2048410440 @default.
• W3191537411 cites W2049722249 @default.
• W3191537411 cites W2068792943 @default.
• W3191537411 cites W2069484292 @default.
• W3191537411 cites W2072429116 @default.
• W3191537411 cites W2075220663 @default.
• W3191537411 cites W207579010 @default.
• W3191537411 cites W2085500398 @default.
• W3191537411 cites W2103149067 @default.
• W3191537411 cites W2110837177 @default.
• W3191537411 cites W2114200005 @default.
• W3191537411 cites W2127465341 @default.
• W3191537411 cites W2128398549 @default.
• W3191537411 cites W2128791326 @default.
• W3191537411 cites W2129171785 @default.
• W3191537411 cites W2136662052 @default.
• W3191537411 cites W2152480384 @default.
• W3191537411 cites W2327934197 @default.
• W3191537411 cites W2467781255 @default.
• W3191537411 cites W2503268391 @default.
• W3191537411 cites W2560327902 @default.
• W3191537411 cites W2582951900 @default.
• W3191537411 cites W2593708726 @default.
• W3191537411 cites W2906054474 @default.
• W3191537411 cites W3027422989 @default.
• W3191537411 cites W4248031042 @default.
• W3191537411 cites W745206253 @default.
• W3191537411 doi "https://doi.org/10.1021/acsbiomaterials.1c00735" @default.
• W3191537411 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8441970" @default.
• W3191537411 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34382772" @default.
• W3191537411 hasPublicationYear "2021" @default.
• W3191537411 type Work @default.
• W3191537411 sameAs 3191537411 @default.
• W3191537411 citedByCount "8" @default.
• W3191537411 countsByYear W31915374112022 @default.
• W3191537411 countsByYear W31915374112023 @default.
• W3191537411 crossrefType "journal-article" @default.
• W3191537411 hasAuthorship W3191537411A5010053080 @default.
• W3191537411 hasAuthorship W3191537411A5011435536 @default.
• W3191537411 hasAuthorship W3191537411A5020199782 @default.
• W3191537411 hasAuthorship W3191537411A5027738338 @default.
• W3191537411 hasAuthorship W3191537411A5037038554 @default.
• W3191537411 hasAuthorship W3191537411A5040628945 @default.
• W3191537411 hasAuthorship W3191537411A5044554319 @default.
• W3191537411 hasAuthorship W3191537411A5060384406 @default.
• W3191537411 hasAuthorship W3191537411A5077269808 @default.
• W3191537411 hasAuthorship W3191537411A5077756071 @default.
• W3191537411 hasBestOaLocation W31915374111 @default.
• W3191537411 hasConcept C115537861 @default.
• W3191537411 hasConcept C127413603 @default.
• W3191537411 hasConcept C150394285 @default.
• W3191537411 hasConcept C159985019 @default.
• W3191537411 hasConcept C171250308 @default.
• W3191537411 hasConcept C178790620 @default.
• W3191537411 hasConcept C185592680 @default.
• W3191537411 hasConcept C192562407 @default.
• W3191537411 hasConcept C2777132085 @default.
• W3191537411 hasConcept C2777335606 @default.

• next