Matches in SemOpenAlex for { <https://semopenalex.org/work/W3191566111> ?p ?o ?g. }
- W3191566111 endingPage "138" @default.
- W3191566111 startingPage "131" @default.
- W3191566111 abstract "To investigate the powerful placebo effects in antidepressant drug trials and their mechanisms, recent pioneering experimental studies showed that expectation manipulation combined with an active placebo attenuated induced sadness. In the present study, we aimed at extending these findings by assessing the psychophysiological response in addition to mere self-report.One hundred and thirteen healthy female students were randomly assigned to a drug expectation group (active placebo, positive treatment expectation), placebo expectation group (active placebo, no treatment expectation), or a no-treatment group (no placebo, no treatment expectation). After placebo intake, sadness was induced by self-deprecating statements using the Velten method combined with sad music, including a rumination phase. Sadness was measured using the Positive and Negative Affect Schedule Expanded Form (PANAS-X). Heart rate and skin conductance were assessed continuously.After mood induction and after rumination, self-reported sadness was significantly lower, and skin conductance level was significantly higher, in the drug expectation group than in the no-treatment group. The mood induction was further accompanied by a heart rate deceleration within all groups.Generalizability is limited by sample selectivity and focusing on sadness as a symptom of depression, exclusively.Expectation-induced placebo effects significantly influenced sadness-correlated changes in autonomic arousal, and not only subjectively reported sadness, indicating that placebo effects in the context of affect are not merely due to subjective response bias. The systematic modification of treatment expectation could be utilized in clinical practice to optimize current therapeutic approaches to improve mood regulation." @default.
- W3191566111 created "2021-08-16" @default.
- W3191566111 creator A5025226620 @default.
- W3191566111 creator A5033597439 @default.
- W3191566111 creator A5081952749 @default.
- W3191566111 creator A5088530915 @default.
- W3191566111 creator A5090784730 @default.
- W3191566111 date "2021-12-01" @default.
- W3191566111 modified "2023-09-27" @default.
- W3191566111 title "Placebo nasal spray protects female participants from experimentally induced sadness and concomitant changes in autonomic arousal" @default.
- W3191566111 cites W1269562257 @default.
- W3191566111 cites W1538854082 @default.
- W3191566111 cites W1974410444 @default.
- W3191566111 cites W1975911018 @default.
- W3191566111 cites W1983627329 @default.
- W3191566111 cites W1984288569 @default.
- W3191566111 cites W1995698752 @default.
- W3191566111 cites W2002225084 @default.
- W3191566111 cites W2019039429 @default.
- W3191566111 cites W2019239430 @default.
- W3191566111 cites W2019524683 @default.
- W3191566111 cites W2020001299 @default.
- W3191566111 cites W2020640591 @default.
- W3191566111 cites W2028864487 @default.
- W3191566111 cites W2037557484 @default.
- W3191566111 cites W2044730465 @default.
- W3191566111 cites W2047969251 @default.
- W3191566111 cites W2056565869 @default.
- W3191566111 cites W2058119571 @default.
- W3191566111 cites W2062838995 @default.
- W3191566111 cites W2066373232 @default.
- W3191566111 cites W2084434457 @default.
- W3191566111 cites W2088577361 @default.
- W3191566111 cites W2101540672 @default.
- W3191566111 cites W2107924467 @default.
- W3191566111 cites W2109590258 @default.
- W3191566111 cites W2115855938 @default.
- W3191566111 cites W2117257450 @default.
- W3191566111 cites W2121942205 @default.
- W3191566111 cites W2126272883 @default.
- W3191566111 cites W2132322340 @default.
- W3191566111 cites W2137575330 @default.
- W3191566111 cites W2156104108 @default.
- W3191566111 cites W2157198497 @default.
- W3191566111 cites W2163940445 @default.
- W3191566111 cites W2167761850 @default.
- W3191566111 cites W2180491479 @default.
- W3191566111 cites W2181235434 @default.
- W3191566111 cites W2314831905 @default.
- W3191566111 cites W2331364533 @default.
- W3191566111 cites W2531210989 @default.
- W3191566111 cites W2733357509 @default.
- W3191566111 cites W2751884637 @default.
- W3191566111 cites W2755406504 @default.
- W3191566111 cites W2796377860 @default.
- W3191566111 cites W2883393306 @default.
- W3191566111 cites W2885815791 @default.
- W3191566111 cites W2947616018 @default.
- W3191566111 cites W2950759421 @default.
- W3191566111 cites W2952183252 @default.
- W3191566111 cites W2953915003 @default.
- W3191566111 cites W3027345916 @default.
- W3191566111 cites W3034863319 @default.
- W3191566111 cites W4211130665 @default.
- W3191566111 cites W4241042631 @default.
- W3191566111 cites W4246572246 @default.
- W3191566111 cites W4253751021 @default.
- W3191566111 doi "https://doi.org/10.1016/j.jad.2021.07.037" @default.
- W3191566111 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34438321" @default.
- W3191566111 hasPublicationYear "2021" @default.
- W3191566111 type Work @default.
- W3191566111 sameAs 3191566111 @default.
- W3191566111 citedByCount "7" @default.
- W3191566111 countsByYear W31915661112022 @default.
- W3191566111 countsByYear W31915661112023 @default.
- W3191566111 crossrefType "journal-article" @default.
- W3191566111 hasAuthorship W3191566111A5025226620 @default.
- W3191566111 hasAuthorship W3191566111A5033597439 @default.
- W3191566111 hasAuthorship W3191566111A5081952749 @default.
- W3191566111 hasAuthorship W3191566111A5088530915 @default.
- W3191566111 hasAuthorship W3191566111A5090784730 @default.
- W3191566111 hasConcept C118552586 @default.
- W3191566111 hasConcept C126322002 @default.
- W3191566111 hasConcept C142724271 @default.
- W3191566111 hasConcept C151730666 @default.
- W3191566111 hasConcept C15744967 @default.
- W3191566111 hasConcept C168563851 @default.
- W3191566111 hasConcept C169900460 @default.
- W3191566111 hasConcept C188353592 @default.
- W3191566111 hasConcept C204787440 @default.
- W3191566111 hasConcept C27081682 @default.
- W3191566111 hasConcept C2776060345 @default.
- W3191566111 hasConcept C2779302386 @default.
- W3191566111 hasConcept C2779343474 @default.
- W3191566111 hasConcept C2779812673 @default.
- W3191566111 hasConcept C2780733359 @default.
- W3191566111 hasConcept C42219234 @default.
- W3191566111 hasConcept C548259974 @default.