FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3191566963> ?p ?o ?g. }

• W3191566963 abstract "Abstract Technologies that increase the efficiency and sustainability of food animal production to provide meat for a growing population are necessary and must be used in a manner consistent with good veterinary practices, approved labeled use, and environmental stewardship. Compounds that bind to beta-adrenergic receptors (β-AR), termed beta-adrenergic receptor ligands (β-ligands), are one such technology and have been in use globally for many years. Though all β-ligands share some similarities in structure and function, the significance of their structural and pharmacological differences is sometimes overlooked. Structural variations in these molecules can affect absorption, distribution, metabolism, and excretion as well as cause substantial differences in biological and metabolic effects. Several β-ligands are available for use specifically in cattle production. Ractopamine and zilpaterol are beta-adrenergic agonists approved to increase weight gain, feed efficiency, and carcass leanness in cattle. They both bind to and activate β1- and β2-AR. Lubabegron is a newly developed selective beta-adrenergic modulator with unique structural and functional features. Lubabegron displays antagonistic behavior at the β1- and β2-AR but agonistic behavior at the β3-AR. Lubabegron is approved for use in cattle to reduce ammonia emissions per unit of live or carcass weight. Additionally, lubabegron can withstand prolonged use as the β3-AR lacks structural features needed for desensitization. Due to these unique features of lubabegron, this new β-ligand provides an additional option in cattle production. The individual properties of each β-ligand should be considered when making risk management decisions, as unique properties result in varying human food safety profiles that can determine appropriate safe β-ligand use." @default.
• W3191566963 created "2021-08-16" @default.
• W3191566963 creator A5006445770 @default.
• W3191566963 creator A5016085931 @default.
• W3191566963 creator A5016423039 @default.
• W3191566963 creator A5034435486 @default.
• W3191566963 date "2021-08-01" @default.
• W3191566963 modified "2023-10-14" @default.
• W3191566963 title "Comparison of beta-ligands used in cattle production: structures, safety, and biological effects" @default.
• W3191566963 cites W105143219 @default.
• W3191566963 cites W11492256 @default.
• W3191566963 cites W136130207 @default.
• W3191566963 cites W1493514243 @default.
• W3191566963 cites W1536021967 @default.
• W3191566963 cites W1603981767 @default.
• W3191566963 cites W161970442 @default.
• W3191566963 cites W19162607 @default.
• W3191566963 cites W1945095845 @default.
• W3191566963 cites W1968838149 @default.
• W3191566963 cites W1973365510 @default.
• W3191566963 cites W1973564077 @default.
• W3191566963 cites W1974281105 @default.
• W3191566963 cites W1977314667 @default.
• W3191566963 cites W1983360254 @default.
• W3191566963 cites W1989366868 @default.
• W3191566963 cites W1990171249 @default.
• W3191566963 cites W1995096515 @default.
• W3191566963 cites W2023237795 @default.
• W3191566963 cites W2039818384 @default.
• W3191566963 cites W2040710601 @default.
• W3191566963 cites W2041146258 @default.
• W3191566963 cites W2044881194 @default.
• W3191566963 cites W2047678030 @default.
• W3191566963 cites W2059704953 @default.
• W3191566963 cites W2064975685 @default.
• W3191566963 cites W2073786511 @default.
• W3191566963 cites W2077256007 @default.
• W3191566963 cites W2078298718 @default.
• W3191566963 cites W2079226836 @default.
• W3191566963 cites W2080144609 @default.
• W3191566963 cites W2081789463 @default.
• W3191566963 cites W2082381320 @default.
• W3191566963 cites W2083072200 @default.
• W3191566963 cites W2101630767 @default.
• W3191566963 cites W2108453642 @default.
• W3191566963 cites W2112544291 @default.
• W3191566963 cites W2118500418 @default.
• W3191566963 cites W2122266551 @default.
• W3191566963 cites W2138057956 @default.
• W3191566963 cites W2138354938 @default.
• W3191566963 cites W2144463342 @default.
• W3191566963 cites W2147247092 @default.
• W3191566963 cites W2246154510 @default.
• W3191566963 cites W2334701948 @default.
• W3191566963 cites W2547271346 @default.
• W3191566963 cites W2739223637 @default.
• W3191566963 cites W2799656331 @default.
• W3191566963 cites W2954902758 @default.
• W3191566963 cites W3101357984 @default.
• W3191566963 cites W4241601583 @default.
• W3191566963 doi "https://doi.org/10.1093/jas/skab094" @default.
• W3191566963 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8326055" @default.
• W3191566963 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34337648" @default.
• W3191566963 hasPublicationYear "2021" @default.
• W3191566963 type Work @default.
• W3191566963 sameAs 3191566963 @default.
• W3191566963 citedByCount "7" @default.
• W3191566963 countsByYear W31915669632021 @default.
• W3191566963 countsByYear W31915669632022 @default.
• W3191566963 countsByYear W31915669632023 @default.
• W3191566963 crossrefType "journal-article" @default.
• W3191566963 hasAuthorship W3191566963A5006445770 @default.
• W3191566963 hasAuthorship W3191566963A5016085931 @default.
• W3191566963 hasAuthorship W3191566963A5016423039 @default.
• W3191566963 hasAuthorship W3191566963A5034435486 @default.
• W3191566963 hasBestOaLocation W31915669631 @default.
• W3191566963 hasConcept C140793950 @default.
• W3191566963 hasConcept C185592680 @default.
• W3191566963 hasConcept C2780505807 @default.
• W3191566963 hasConcept C2908647359 @default.
• W3191566963 hasConcept C71924100 @default.
• W3191566963 hasConcept C86803240 @default.
• W3191566963 hasConcept C99454951 @default.
• W3191566963 hasConceptScore W3191566963C140793950 @default.
• W3191566963 hasConceptScore W3191566963C185592680 @default.
• W3191566963 hasConceptScore W3191566963C2780505807 @default.
• W3191566963 hasConceptScore W3191566963C2908647359 @default.
• W3191566963 hasConceptScore W3191566963C71924100 @default.
• W3191566963 hasConceptScore W3191566963C86803240 @default.
• W3191566963 hasConceptScore W3191566963C99454951 @default.
• W3191566963 hasFunder F4320307776 @default.
• W3191566963 hasFunder F4320313885 @default.
• W3191566963 hasFunder F4320333372 @default.
• W3191566963 hasIssue "8" @default.
• W3191566963 hasLocation W31915669631 @default.
• W3191566963 hasLocation W31915669632 @default.
• W3191566963 hasLocation W31915669633 @default.
• W3191566963 hasOpenAccess W3191566963 @default.
• W3191566963 hasPrimaryLocation W31915669631 @default.
• W3191566963 hasRelatedWork W1923988655 @default.

• next