FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3191586452> ?p ?o ?g. }

• W3191586452 endingPage "1182" @default.
• W3191586452 startingPage "1175" @default.
• W3191586452 abstract "Alzheimer's disease is a common progressive neurodegenerative disorder in the elderly. Diffusion tensor imaging (DTI) has been widely used to explore structural integrity and to describe white matter degeneration in Alzheimer's disease. Previous research has indicated that the change of connections between white matter fiber tracts is very important for investigating the brain function of Alzheimer's disease patients. However, whether white matter features can be used as potential biomarkers for predicting Alzheimer's disease tendency requires more in-depth research. In this study, we investigated the relationship between the damage in white matter tracts and the decline of cognitive function in Alzheimer's disease. DTI data were collected from 38 Alzheimer's disease patients and 30 normal controls. Fiber assignment by continuous tracking approach was used to establish connections between different brain regions of the whole brain, network-based statistical analysis and support vector machine classification analysis were used to explore the connection of whole-brain fiber bundles between the two groups. Most importantly, our results showed that the connections between brain regions of Alzheimer's disease patients were damaged, and the damage were mainly located in the right hemisphere, there was a certain degree of lateralization effect. Using whole-brain fiber bundle connection network as a feature for classification, we found it helped to improve the classification accuracy in Alzheimer's disease patients, which is useful for early clinical diagnosis of Alzheimer's disease. These findings further suggested that we can use the whole-brain fiber bundle connection network of Alzheimer's disease patients as a potential diagnostic indicator of Alzheimer's disease in the future." @default.
• W3191586452 created "2021-08-16" @default.
• W3191586452 creator A5000925508 @default.
• W3191586452 creator A5030054597 @default.
• W3191586452 creator A5035209529 @default.
• W3191586452 creator A5068049331 @default.
• W3191586452 creator A5070538645 @default.
• W3191586452 creator A5076036593 @default.
• W3191586452 creator A5076626946 @default.
• W3191586452 creator A5077242074 @default.
• W3191586452 date "2021-07-30" @default.
• W3191586452 modified "2023-09-30" @default.
• W3191586452 title "Changes in the connection network of whole-brain fiber tracts in patients with Alzheimer’s disease have a tendency of lateralization" @default.
• W3191586452 cites W1646986031 @default.
• W3191586452 cites W1975504492 @default.
• W3191586452 cites W1986411734 @default.
• W3191586452 cites W1994690989 @default.
• W3191586452 cites W2004757203 @default.
• W3191586452 cites W2015227273 @default.
• W3191586452 cites W2044329307 @default.
• W3191586452 cites W2046699283 @default.
• W3191586452 cites W2048605353 @default.
• W3191586452 cites W2077905398 @default.
• W3191586452 cites W2117917111 @default.
• W3191586452 cites W2123649587 @default.
• W3191586452 cites W2127610265 @default.
• W3191586452 cites W2133003941 @default.
• W3191586452 cites W2617471883 @default.
• W3191586452 cites W3014359006 @default.
• W3191586452 cites W3137667308 @default.
• W3191586452 cites W904184522 @default.
• W3191586452 doi "https://doi.org/10.1097/wnr.0000000000001708" @default.
• W3191586452 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34334777" @default.
• W3191586452 hasPublicationYear "2021" @default.
• W3191586452 type Work @default.
• W3191586452 sameAs 3191586452 @default.
• W3191586452 citedByCount "1" @default.
• W3191586452 countsByYear W31915864522023 @default.
• W3191586452 crossrefType "journal-article" @default.
• W3191586452 hasAuthorship W3191586452A5000925508 @default.
• W3191586452 hasAuthorship W3191586452A5030054597 @default.
• W3191586452 hasAuthorship W3191586452A5035209529 @default.
• W3191586452 hasAuthorship W3191586452A5068049331 @default.
• W3191586452 hasAuthorship W3191586452A5070538645 @default.
• W3191586452 hasAuthorship W3191586452A5076036593 @default.
• W3191586452 hasAuthorship W3191586452A5076626946 @default.
• W3191586452 hasAuthorship W3191586452A5077242074 @default.
• W3191586452 hasConcept C126838900 @default.
• W3191586452 hasConcept C142724271 @default.
• W3191586452 hasConcept C143409427 @default.
• W3191586452 hasConcept C149550507 @default.
• W3191586452 hasConcept C15744967 @default.
• W3191586452 hasConcept C169760540 @default.
• W3191586452 hasConcept C2779134260 @default.
• W3191586452 hasConcept C2781192897 @default.
• W3191586452 hasConcept C502032728 @default.
• W3191586452 hasConcept C71924100 @default.
• W3191586452 hasConcept C79840881 @default.
• W3191586452 hasConceptScore W3191586452C126838900 @default.
• W3191586452 hasConceptScore W3191586452C142724271 @default.
• W3191586452 hasConceptScore W3191586452C143409427 @default.
• W3191586452 hasConceptScore W3191586452C149550507 @default.
• W3191586452 hasConceptScore W3191586452C15744967 @default.
• W3191586452 hasConceptScore W3191586452C169760540 @default.
• W3191586452 hasConceptScore W3191586452C2779134260 @default.
• W3191586452 hasConceptScore W3191586452C2781192897 @default.
• W3191586452 hasConceptScore W3191586452C502032728 @default.
• W3191586452 hasConceptScore W3191586452C71924100 @default.
• W3191586452 hasConceptScore W3191586452C79840881 @default.
• W3191586452 hasIssue "14" @default.
• W3191586452 hasLocation W31915864521 @default.
• W3191586452 hasLocation W31915864522 @default.
• W3191586452 hasOpenAccess W3191586452 @default.
• W3191586452 hasPrimaryLocation W31915864521 @default.
• W3191586452 hasRelatedWork W1974778464 @default.
• W3191586452 hasRelatedWork W1979876709 @default.
• W3191586452 hasRelatedWork W2070933122 @default.
• W3191586452 hasRelatedWork W2102753837 @default.
• W3191586452 hasRelatedWork W2107169104 @default.
• W3191586452 hasRelatedWork W2343147176 @default.
• W3191586452 hasRelatedWork W2525824058 @default.
• W3191586452 hasRelatedWork W2751461426 @default.
• W3191586452 hasRelatedWork W2949115936 @default.
• W3191586452 hasRelatedWork W4366213440 @default.
• W3191586452 hasVolume "32" @default.
• W3191586452 isParatext "false" @default.
• W3191586452 isRetracted "false" @default.
• W3191586452 magId "3191586452" @default.
• W3191586452 workType "article" @default.