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• W3191816488 abstract "Abstract The nutrient composition of breast milk alters during lactation, and maternal BMI adds more intricacy into its complexity. We aimed to compare leptin, ghrelin, adiponectin, and IGF-1 levels of pre-feed and post-feed breast milk in mothers with obesity and normal weight, and tried to determine their effects on infants’ growth over weight for length z-score. 20 obese and 20 normal weight mothers with 2 month old infants were enrolled in this case-control study. 5 mL pre-feed breast milk and 5 mL post-feed breast milk were collected. Breast milk leptin, ghrelin, adiponectin, and insulin like growth factor-1 were measured by commercial kits. The pre-feed breast milk of mothers with obesity had significantly higher levels of ghrelin than mothers with normal weight (p= 0.025), whereas the post-feed breast milk of mothers with normal weight had higher levels of adiponectin than the mothers with obesity (p= 0.010). No significant differences were observed in leptin and IGF-1 levels between the two groups. Post-feed breast milk IGF-1 levels of mothers with obesity were correlated with infant’s weight for length z-score at 2 months (r= -0.476; p= 0.034). In linear regression models, parity affected the ghrelin in pre-feed breast milk (p= 0.025). Our results revealed that maternal pre-pregnancy BMI was associated with breast milk components." @default.
• W3191816488 created "2021-08-16" @default.
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• W3191816488 date "2021-08-05" @default.
• W3191816488 modified "2023-10-14" @default.
• W3191816488 title "The Association of Pre-Pregnancy BMI On Leptin, Ghrelin, Adiponectin, and IGF-1 In Breast Milk, A Case Control Study" @default.
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• W3191816488 doi "https://doi.org/10.1017/s0007114521002932" @default.
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