FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3192165816> ?p ?o ?g. }

• W3192165816 abstract "Abstract Study question Is there any difference in this technique(swim-in) according to clinical results in ICSI cycles? Summary answer Fertilization rates are significantly better with this new technique(swim-in). There is no difference in pregnancy and ongoing pregnancy rates between swim-in and DGS techniques. What is known already Sperm separation is crucial in assisted reproductive technologies, based on different principles like migration, filtration, or density gradient centrifugation techniques. However, there are some studies that centrifugation steps and using gradient solutions may increase sperm DNA fragmentation. On the other hand, multiple contacts to different plastic surfaces such as pipettes, plastic tubes, etc., and also pipetting the ejaculate in sperm preparation may have detrimental effects. The ideal sperm separation technique should be non-invasive, not time-consuming, easy, and cost-effective, not cause sperm damage or non-physiological alterations of the separated sperm cells, eliminate dead spermatozoa and other cells, including leukocytes. Study design, size, duration This is a prospective randomized study between 01/02/2019...01/01/2021. Sperms were prepared either with this new technique that we call “swim-in”(n = 359) or with density gradient centrifugation(n = 404) before microinjection (ICSI). Fertilization rates, clinical pregnancy rates, and on-going pregnancy rates were compared between groups. Sperm motility is less than%20 patients are not included in the study. t-test and Chi-square test used. p &lt; 0.05 significant. Participants/materials, setting, methods For this new centrifugation free technique(swim-in), a Braun injector, 21G green needle, and sperm washing medium are used. First, we pulled a 0.5 ml sperm wash medium in a Braun injector. After sperm liquefaction, we put Braun injector with the needle in the sperm cap perpendicularly and waited 30 minutes at 37-degree Celcius. Sperms swam through the needle to the injector used for ICSI. For DGC sperms were prepared according to the 2015 WHO manual. Main results and the role of chance: We try to make a centrifugation-free, gentle, cost-effective, and easy sperm preparation technique and called it a swim-in technique. Groups were comparable according to mean age, collected oocyte numbers, and oocyte maturation ratios. Fertilization rates are%73,2(1786/2438) vs%66,9(2167/3237) respectively for swim-in and DGC groups. Clinical pregnancy rates are%45,1 vs%42,3 respectively for swim-in and DGC groups. On-going pregnancy rates are%41,5 vs%39,6 for swim-in and DGC respectively. There is a significant difference between the two techniques according to fertilization rates but no difference according to clinical pregnancy and ongoing pregnancy rates. Limitations, reasons for caution Sperms can move by their own motility from ejaculate to the sperm washing medium for that reason with severe sperm problem patients are not suitable for this technique. Wider implications of the findings: This technique is centrifugation free so there are no detrimental g-forces. The needle used may mimic the physiological environment like Uterine Tube. Alternative sperm washing mediums like follicular fluid or chemical attractor progesterone rich medium can be used.DNA fragmentation rates and live birth rates should be established for future aspect. Trial registration number Not applicable" @default.
• W3192165816 created "2021-08-16" @default.
• W3192165816 creator A5008546256 @default.
• W3192165816 creator A5037905781 @default.
• W3192165816 creator A5051367941 @default.
• W3192165816 creator A5064417040 @default.
• W3192165816 creator A5072317236 @default.
• W3192165816 creator A5078937811 @default.
• W3192165816 date "2021-07-01" @default.
• W3192165816 modified "2023-09-26" @default.
• W3192165816 title "P–012 A new sperm preparation technique for ICSI" @default.
• W3192165816 doi "https://doi.org/10.1093/humrep/deab130.011" @default.
• W3192165816 hasPublicationYear "2021" @default.
• W3192165816 type Work @default.
• W3192165816 sameAs 3192165816 @default.
• W3192165816 citedByCount "0" @default.
• W3192165816 crossrefType "journal-article" @default.
• W3192165816 hasAuthorship W3192165816A5008546256 @default.
• W3192165816 hasAuthorship W3192165816A5037905781 @default.
• W3192165816 hasAuthorship W3192165816A5051367941 @default.
• W3192165816 hasAuthorship W3192165816A5064417040 @default.
• W3192165816 hasAuthorship W3192165816A5072317236 @default.
• W3192165816 hasAuthorship W3192165816A5078937811 @default.
• W3192165816 hasConcept C105702510 @default.
• W3192165816 hasConcept C126322002 @default.
• W3192165816 hasConcept C127315564 @default.
• W3192165816 hasConcept C132946820 @default.
• W3192165816 hasConcept C147789679 @default.
• W3192165816 hasConcept C151552171 @default.
• W3192165816 hasConcept C153911025 @default.
• W3192165816 hasConcept C16685009 @default.
• W3192165816 hasConcept C185592680 @default.
• W3192165816 hasConcept C2776537878 @default.
• W3192165816 hasConcept C2777005246 @default.
• W3192165816 hasConcept C2777632594 @default.
• W3192165816 hasConcept C2777688143 @default.
• W3192165816 hasConcept C2778093475 @default.
• W3192165816 hasConcept C2778278907 @default.
• W3192165816 hasConcept C2779234561 @default.
• W3192165816 hasConcept C2781087480 @default.
• W3192165816 hasConcept C29456083 @default.
• W3192165816 hasConcept C3018023364 @default.
• W3192165816 hasConcept C43617362 @default.
• W3192165816 hasConcept C500014431 @default.
• W3192165816 hasConcept C512716672 @default.
• W3192165816 hasConcept C54355233 @default.
• W3192165816 hasConcept C71924100 @default.
• W3192165816 hasConcept C7623868 @default.
• W3192165816 hasConcept C86803240 @default.
• W3192165816 hasConcept C88972607 @default.
• W3192165816 hasConceptScore W3192165816C105702510 @default.
• W3192165816 hasConceptScore W3192165816C126322002 @default.
• W3192165816 hasConceptScore W3192165816C127315564 @default.
• W3192165816 hasConceptScore W3192165816C132946820 @default.
• W3192165816 hasConceptScore W3192165816C147789679 @default.
• W3192165816 hasConceptScore W3192165816C151552171 @default.
• W3192165816 hasConceptScore W3192165816C153911025 @default.
• W3192165816 hasConceptScore W3192165816C16685009 @default.
• W3192165816 hasConceptScore W3192165816C185592680 @default.
• W3192165816 hasConceptScore W3192165816C2776537878 @default.
• W3192165816 hasConceptScore W3192165816C2777005246 @default.
• W3192165816 hasConceptScore W3192165816C2777632594 @default.
• W3192165816 hasConceptScore W3192165816C2777688143 @default.
• W3192165816 hasConceptScore W3192165816C2778093475 @default.
• W3192165816 hasConceptScore W3192165816C2778278907 @default.
• W3192165816 hasConceptScore W3192165816C2779234561 @default.
• W3192165816 hasConceptScore W3192165816C2781087480 @default.
• W3192165816 hasConceptScore W3192165816C29456083 @default.
• W3192165816 hasConceptScore W3192165816C3018023364 @default.
• W3192165816 hasConceptScore W3192165816C43617362 @default.
• W3192165816 hasConceptScore W3192165816C500014431 @default.
• W3192165816 hasConceptScore W3192165816C512716672 @default.
• W3192165816 hasConceptScore W3192165816C54355233 @default.
• W3192165816 hasConceptScore W3192165816C71924100 @default.
• W3192165816 hasConceptScore W3192165816C7623868 @default.
• W3192165816 hasConceptScore W3192165816C86803240 @default.
• W3192165816 hasConceptScore W3192165816C88972607 @default.
• W3192165816 hasIssue "Supplement_1" @default.
• W3192165816 hasLocation W31921658161 @default.
• W3192165816 hasOpenAccess W3192165816 @default.
• W3192165816 hasPrimaryLocation W31921658161 @default.
• W3192165816 hasRelatedWork W192339950 @default.
• W3192165816 hasRelatedWork W2013932387 @default.
• W3192165816 hasRelatedWork W2084561649 @default.
• W3192165816 hasRelatedWork W2310203467 @default.
• W3192165816 hasRelatedWork W2367087154 @default.
• W3192165816 hasRelatedWork W2976439174 @default.
• W3192165816 hasRelatedWork W3192165816 @default.
• W3192165816 hasRelatedWork W4256147281 @default.
• W3192165816 hasRelatedWork W848118522 @default.
• W3192165816 hasRelatedWork W2149461651 @default.
• W3192165816 hasVolume "36" @default.
• W3192165816 isParatext "false" @default.
• W3192165816 isRetracted "false" @default.
• W3192165816 magId "3192165816" @default.
• W3192165816 workType "article" @default.