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- W3192356670 abstract "Several novel systemic cancer therapies have evolved in the last two decades. Oncology drug development has moved from “cytotoxic” agents to “targeted” drugs. More recently, immune modulation by drugs or cellular therapies has been added to anti-cancer armamentarium.[1] Advances in basic cancer biology have aided these developments. However, we are far from achieving “cure” or “control” of most advanced cancers. There is a constant need to innovate and develop therapies to “outwit” the ever-mutating cancer cell. Canonical drug development models are painstakingly slow and very expensive and hence there is need to look for alternative options. It is in this space that drug repurposing fits whereby an existing drug (used for other nononcological indications) is used for treating tumors by virtue of its action on some of the “targets” presented by cancer. The increased understanding of the hallmarks of cancer and the development of various data-driven approaches have facilitated the science of drug repurposing in oncology.[2]" @default.
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- W3192356670 date "2021-04-01" @default.
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- W3192356670 title "Drug Repurposing in Oncology" @default.
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- W3192356670 doi "https://doi.org/10.1055/s-0041-1733825" @default.
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