Matches in SemOpenAlex for { <https://semopenalex.org/work/W3192649728> ?p ?o ?g. }
- W3192649728 endingPage "30" @default.
- W3192649728 startingPage "30" @default.
- W3192649728 abstract "The aim of this work was to reuse a fish processing waste, shrimp head powder (SHP), for the production of prodigiosin (PG) via microbial technology and to assess its potential bioactivities. PG was produced in a 12 L-bioreactor system, and the highest PG productivity of 6310 mg L−1 was achieved when Serratia marcescens CC17 was used for fermentation in a novel designed medium (6.75 L) containing 1.5% C/N source (SHP/casein = 9/1), 0.02% K2SO4, ans 0.025% Ca3(PO4)2, with initial pH 7.0, and fermentation was performed at 28 °C for 8 h. The purified PG showed moderate antioxidants, efficient anti-NO (anti-nitric oxide), and acetylcholinesterase (AChE) inhibitory activities. In a docking study, PG showed better binding energy scores (−12.3 kcal/mol) and more interactions (6 linkages) with several prominent amino acids in the biding sites on AChE that were superior to those of Berberine chloride (−10.8 kcal/mol and one linkage). Notably, this is the first investigation using shrimp heads for the mass bioproduction of PG with high productivity, and Ca3(PO4)2 salt was also newly found to significantly enhance PG production by S. marcescens. This study also provided available data on the anti-NO and anti-AChE effects of PG, especially from the docking simulation PG towards AChE that was described for the first time in this study. The above results suggest that SHP is a good material for the cost-effective bioproduction of PG, which is a potential candidate for anti-NO and anti-Alzheimer drugs." @default.
- W3192649728 created "2021-08-16" @default.
- W3192649728 creator A5013889869 @default.
- W3192649728 creator A5016674337 @default.
- W3192649728 creator A5025025459 @default.
- W3192649728 creator A5031435786 @default.
- W3192649728 creator A5046896491 @default.
- W3192649728 creator A5071754735 @default.
- W3192649728 date "2021-08-11" @default.
- W3192649728 modified "2023-10-16" @default.
- W3192649728 title "Bioproduction of Prodigiosin from Fishery Processing Waste Shrimp Heads and Evaluation of Its Potential Bioactivities" @default.
- W3192649728 cites W1806025101 @default.
- W3192649728 cites W1974479328 @default.
- W3192649728 cites W1978316610 @default.
- W3192649728 cites W1978979892 @default.
- W3192649728 cites W1984728798 @default.
- W3192649728 cites W1991894150 @default.
- W3192649728 cites W2033608236 @default.
- W3192649728 cites W2033898136 @default.
- W3192649728 cites W2041953221 @default.
- W3192649728 cites W2043880408 @default.
- W3192649728 cites W2053798679 @default.
- W3192649728 cites W2065654031 @default.
- W3192649728 cites W2077632386 @default.
- W3192649728 cites W2083112508 @default.
- W3192649728 cites W2086197042 @default.
- W3192649728 cites W2090467197 @default.
- W3192649728 cites W2102681027 @default.
- W3192649728 cites W2108331752 @default.
- W3192649728 cites W2127734104 @default.
- W3192649728 cites W2131873950 @default.
- W3192649728 cites W2137905276 @default.
- W3192649728 cites W2150969390 @default.
- W3192649728 cites W2259524194 @default.
- W3192649728 cites W2477289289 @default.
- W3192649728 cites W2517268481 @default.
- W3192649728 cites W2559337600 @default.
- W3192649728 cites W2602845604 @default.
- W3192649728 cites W2607343546 @default.
- W3192649728 cites W2750965499 @default.
- W3192649728 cites W2767866515 @default.
- W3192649728 cites W2781733595 @default.
- W3192649728 cites W2787942959 @default.
- W3192649728 cites W2793968373 @default.
- W3192649728 cites W2802451478 @default.
- W3192649728 cites W2803744340 @default.
- W3192649728 cites W2886973930 @default.
- W3192649728 cites W2893930979 @default.
- W3192649728 cites W2899988305 @default.
- W3192649728 cites W2908218902 @default.
- W3192649728 cites W2939529177 @default.
- W3192649728 cites W2941690149 @default.
- W3192649728 cites W2943849196 @default.
- W3192649728 cites W2946052026 @default.
- W3192649728 cites W2952248180 @default.
- W3192649728 cites W2955138947 @default.
- W3192649728 cites W2975102006 @default.
- W3192649728 cites W2976674273 @default.
- W3192649728 cites W2979842092 @default.
- W3192649728 cites W2996586986 @default.
- W3192649728 cites W3006425034 @default.
- W3192649728 cites W3013340991 @default.
- W3192649728 cites W3015448491 @default.
- W3192649728 cites W3034495067 @default.
- W3192649728 cites W3035723386 @default.
- W3192649728 cites W3049891058 @default.
- W3192649728 cites W3088141277 @default.
- W3192649728 cites W3094181510 @default.
- W3192649728 cites W3097471054 @default.
- W3192649728 cites W3110772734 @default.
- W3192649728 cites W3136707122 @default.
- W3192649728 cites W3138455554 @default.
- W3192649728 cites W3158949405 @default.
- W3192649728 cites W3164407775 @default.
- W3192649728 cites W3170643337 @default.
- W3192649728 doi "https://doi.org/10.3390/fishes6030030" @default.
- W3192649728 hasPublicationYear "2021" @default.
- W3192649728 type Work @default.
- W3192649728 sameAs 3192649728 @default.
- W3192649728 citedByCount "14" @default.
- W3192649728 countsByYear W31926497282021 @default.
- W3192649728 countsByYear W31926497282022 @default.
- W3192649728 countsByYear W31926497282023 @default.
- W3192649728 crossrefType "journal-article" @default.
- W3192649728 hasAuthorship W3192649728A5013889869 @default.
- W3192649728 hasAuthorship W3192649728A5016674337 @default.
- W3192649728 hasAuthorship W3192649728A5025025459 @default.
- W3192649728 hasAuthorship W3192649728A5031435786 @default.
- W3192649728 hasAuthorship W3192649728A5046896491 @default.
- W3192649728 hasAuthorship W3192649728A5071754735 @default.
- W3192649728 hasBestOaLocation W31926497281 @default.
- W3192649728 hasConcept C100544194 @default.
- W3192649728 hasConcept C104317684 @default.
- W3192649728 hasConcept C181199279 @default.
- W3192649728 hasConcept C185592680 @default.
- W3192649728 hasConcept C2776309202 @default.
- W3192649728 hasConcept C2776841996 @default.
- W3192649728 hasConcept C2778816929 @default.