Matches in SemOpenAlex for { <https://semopenalex.org/work/W3193312948> ?p ?o ?g. }
- W3193312948 endingPage "470" @default.
- W3193312948 startingPage "463" @default.
- W3193312948 abstract "In this study, the expression of the androgen receptor (AR) and estrogen receptor alpha (ERα) in testicular tissue of male patients with obstructive azoospermia (OA) and non-obstructive azoospermia (NOA) were evaluated by immunohistochemistry. NOA (n = 23) and OA (n = 21) groups were created according to clinical and laboratory archival records. Testicular sperm extraction tissue sections were evaluated according to Johnsen's tubular biopsy scoring (JTBS) method. ERα and AR immunostaining results were evaluated semiquantitatively. Serum follicle-stimulating hormone (FSH), luteinizing hormone (LH), testosterone, and estradiol were analyzed. Serum FSH and LH concentrations were greater, and testosterone concentrations were lower than the normal values in the NOA group, whereas the OA group revealed normal hormonal values. Serum estradiol concentrations in groups were in the normal range. JTBSs were significantly lower in the NOA group. Decreased AR expression and increased ERα expression were observed in the NOA group compared to the OA group. This suggests that ERα and AR are expressed in Sertoli cells, Leydig cells, and myoid cells and are required for normal testicular function. Decreased expression of the AR and increased expression of ERα in the testis may negatively affect spermatogenesis.Abbreviations: AR: androgen receptor; ER: estrogen receptor; ERα: estrogen receptor alpha; FSH: follicle-stimulating hormone; JTBS: Johnsen's tubular biopsy scoring; LH: luteinizing hormone; NOA: non-obstructive azoospermia; OA: obstructive azoospermia; TESE: testicular sperm extraction." @default.
- W3193312948 created "2021-08-30" @default.
- W3193312948 creator A5011567487 @default.
- W3193312948 creator A5017768792 @default.
- W3193312948 creator A5018026134 @default.
- W3193312948 creator A5030563674 @default.
- W3193312948 creator A5038734957 @default.
- W3193312948 creator A5041342666 @default.
- W3193312948 creator A5058928816 @default.
- W3193312948 creator A5069528605 @default.
- W3193312948 creator A5075047240 @default.
- W3193312948 creator A5091625057 @default.
- W3193312948 date "2021-08-22" @default.
- W3193312948 modified "2023-09-27" @default.
- W3193312948 title "Immunohistochemical examination of androgen receptor and estrogen receptor alpha expressions in obstructive and non-obstructive azoospermia" @default.
- W3193312948 cites W1963979543 @default.
- W3193312948 cites W1977027676 @default.
- W3193312948 cites W1986192649 @default.
- W3193312948 cites W1989582021 @default.
- W3193312948 cites W2006594902 @default.
- W3193312948 cites W2007180694 @default.
- W3193312948 cites W2011994682 @default.
- W3193312948 cites W2016995707 @default.
- W3193312948 cites W2019721505 @default.
- W3193312948 cites W2044940346 @default.
- W3193312948 cites W2048005116 @default.
- W3193312948 cites W2051078744 @default.
- W3193312948 cites W2061564710 @default.
- W3193312948 cites W2073761956 @default.
- W3193312948 cites W2076642347 @default.
- W3193312948 cites W2078361775 @default.
- W3193312948 cites W2094051883 @default.
- W3193312948 cites W2109218990 @default.
- W3193312948 cites W2109974307 @default.
- W3193312948 cites W2113344999 @default.
- W3193312948 cites W2258053387 @default.
- W3193312948 cites W2600908019 @default.
- W3193312948 cites W2618323132 @default.
- W3193312948 cites W2792373423 @default.
- W3193312948 cites W2911602993 @default.
- W3193312948 cites W3005126946 @default.
- W3193312948 cites W3082067571 @default.
- W3193312948 cites W4237395980 @default.
- W3193312948 doi "https://doi.org/10.1080/19396368.2021.1958094" @default.
- W3193312948 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34420467" @default.
- W3193312948 hasPublicationYear "2021" @default.
- W3193312948 type Work @default.
- W3193312948 sameAs 3193312948 @default.
- W3193312948 citedByCount "4" @default.
- W3193312948 countsByYear W31933129482022 @default.
- W3193312948 crossrefType "journal-article" @default.
- W3193312948 hasAuthorship W3193312948A5011567487 @default.
- W3193312948 hasAuthorship W3193312948A5017768792 @default.
- W3193312948 hasAuthorship W3193312948A5018026134 @default.
- W3193312948 hasAuthorship W3193312948A5030563674 @default.
- W3193312948 hasAuthorship W3193312948A5038734957 @default.
- W3193312948 hasAuthorship W3193312948A5041342666 @default.
- W3193312948 hasAuthorship W3193312948A5058928816 @default.
- W3193312948 hasAuthorship W3193312948A5069528605 @default.
- W3193312948 hasAuthorship W3193312948A5075047240 @default.
- W3193312948 hasAuthorship W3193312948A5091625057 @default.
- W3193312948 hasConcept C121608353 @default.
- W3193312948 hasConcept C123765429 @default.
- W3193312948 hasConcept C126322002 @default.
- W3193312948 hasConcept C134018914 @default.
- W3193312948 hasConcept C16685009 @default.
- W3193312948 hasConcept C2777164284 @default.
- W3193312948 hasConcept C2777420699 @default.
- W3193312948 hasConcept C2777688143 @default.
- W3193312948 hasConcept C2778575703 @default.
- W3193312948 hasConcept C2779234561 @default.
- W3193312948 hasConcept C2779279165 @default.
- W3193312948 hasConcept C2779279991 @default.
- W3193312948 hasConcept C2780192828 @default.
- W3193312948 hasConcept C35035537 @default.
- W3193312948 hasConcept C530470458 @default.
- W3193312948 hasConcept C54355233 @default.
- W3193312948 hasConcept C61367390 @default.
- W3193312948 hasConcept C71315377 @default.
- W3193312948 hasConcept C71924100 @default.
- W3193312948 hasConcept C84606932 @default.
- W3193312948 hasConcept C86803240 @default.
- W3193312948 hasConceptScore W3193312948C121608353 @default.
- W3193312948 hasConceptScore W3193312948C123765429 @default.
- W3193312948 hasConceptScore W3193312948C126322002 @default.
- W3193312948 hasConceptScore W3193312948C134018914 @default.
- W3193312948 hasConceptScore W3193312948C16685009 @default.
- W3193312948 hasConceptScore W3193312948C2777164284 @default.
- W3193312948 hasConceptScore W3193312948C2777420699 @default.
- W3193312948 hasConceptScore W3193312948C2777688143 @default.
- W3193312948 hasConceptScore W3193312948C2778575703 @default.
- W3193312948 hasConceptScore W3193312948C2779234561 @default.
- W3193312948 hasConceptScore W3193312948C2779279165 @default.
- W3193312948 hasConceptScore W3193312948C2779279991 @default.
- W3193312948 hasConceptScore W3193312948C2780192828 @default.
- W3193312948 hasConceptScore W3193312948C35035537 @default.
- W3193312948 hasConceptScore W3193312948C530470458 @default.
- W3193312948 hasConceptScore W3193312948C54355233 @default.