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• W3193378957 abstract "Objective: To explore the treatment effects of the fractional carbon dioxide laser on contracture scars. Methods: A retrospective before-after control study was conducted. From December 2016 to April 2021, 16 patients (7 males and 9 females, aged 3-49 years) with contracture scars causing impaired function of the adjacent joint were admitted to Shanghai Ninth People's Hospital of Shanghai Jiao Tong University School of Medicine. Eighteen joint scars of 16 patients were treated with fractional carbon dioxide laser every 2-3 months until the joint retained its normal range of motion or the effect plateaued. The treatment times of each patient were recorded. Before the first intervention and 6 months after the last treatment, the range of motion of the affected joint were measured in each patient, and the difference was calculated, meanwhile, the Vancouver Scar Scale (VSS) was used to evaluate the scar of each patient. In the treatment of 1 joint scar in each of 6 patients (totally 6 treatments), the range of motion before the current treatment, immediately after treatment, and at the first follow-up after treatment was noted, and the differences between the range before and immediately after the treatment as well as the range before and at the first follow-up after treatment were calculated. Adverse effects in the treatment area caused by the treatment were noted. At the last follow-up, a self-made questionnaire was used to collect the implementation status of the physical therapy and other scar management modalities during the treatment interval and follow-up period. Data were statistically analyzed with Wilcoxon rank sum test. Results: Eighteen joint scars in 16 patients went through 2 (1, 3) times of treatments by fractional carbon dioxide laser. The range of motion of the affected joint of 16 patients 6 months after the last treatment was 56.5 (39.0, 128.8)°, notably higher than 38.4 (22.9, 116.3)° before the first treatment (Z=-3.724, P<0.01), which was improved by 17.4 (8.0, 24.1)°. The vascular distribution, softness, and thickness scores, and total score in VSS scoring of scars of 16 patients 6 months after the last treatment were significantly lower than those before the first treatment (Z=-2.989, -3.762, -2.814, -3.739, P<0.01), with the most obvious improvement in softness. In 6 treatments, the range of motion immediately after treatment and at the first follow-up of (2.5±0.6) months after treatment were 156.2 (148.0, 164.2)° and 160.2 (156.7, 166.4)°, both notably higher than 151.4 (145.7, 155.3)° before treatment (Z=-2.201, -2.201, P<0.05), which were improved by 9.1 (4.4, 13.0)° and 13.1 (8.0, 15.7)°, respectively. Adverse effects such as blisters, infection, or hypertrophic scar formation was not observed in the treatment area of 16 patients. Most patients adopted physical therapy, compression, silicone gel or sheets, and braces during the treatment interval and follow-up period. Conclusions: The fractional carbon dioxide laser can soften the scar and increase the range of motion of the affected joint, which is suitable for the treatment of mild contracture scars." @default.
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• W3193378957 date "2021-07-23" @default.
• W3193378957 modified "2023-09-24" @default.
• W3193378957 title "Analysis of treatment effects of fractional carbon dioxide laser on contracture scars" @default.
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