Matches in SemOpenAlex for { <https://semopenalex.org/work/W3193396491> ?p ?o ?g. }
- W3193396491 endingPage "144" @default.
- W3193396491 startingPage "137" @default.
- W3193396491 abstract "Patients in cardiogenic shock supported with venoarterial extracorporeal membrane oxygenation (VA-ECMO) may experience severe complications from reduced left ventricular (LV) unloading and increased cardiac afterload. These effects are usually modified by adding a percutaneous direct Impella vent or surgical LV vent on top of VA-ECMO in selected patients. However, direct comparisons between 2 LV unloading strategies in patients with cardiogenic shock due to myocardial infarction are lacking. Therefore, we sought to investigate the impact of these 2 different approaches.We enrolled 112 patients treated with an Impella or surgical LV vent during VA-ECMO support between January 2014 and February 2020. The primary endpoint was 30-day mortality. Secondary endpoints included rates of myocardial recovery or transition to durable mechanical circulatory support. Additionally, we assessed adverse events such as peripheral ischaemic complications requiring intervention, sepsis and ischaemic stroke.At 30 days, 38 patients in the Impella group (54%) and 26 patients in the surgical LV vent group (63%) had died (relative risk with Impella 0.78, 95% confidence interval 0.47-1.30; P = 0.35). Impella group and the surgical LV vent group differed significantly with respect to the secondary end points including rates of myocardial recovery (24% and 7%, respectively; P = 0.022) and rates of durable mechanical circulatory support (17% and 42%, P = 0.012). Complication rates were not statistically different between the 2 groups.The use of Impella device as therapeutic unloading therapy during VA-ECMO did not significantly reduce 30-day mortality compared to surgical LV vent in patients with cardiogenic shock due to acute myocardial infarction." @default.
- W3193396491 created "2021-08-30" @default.
- W3193396491 creator A5008918690 @default.
- W3193396491 creator A5011836477 @default.
- W3193396491 creator A5013542824 @default.
- W3193396491 creator A5015237090 @default.
- W3193396491 creator A5035687829 @default.
- W3193396491 creator A5043551594 @default.
- W3193396491 creator A5045803776 @default.
- W3193396491 creator A5051809336 @default.
- W3193396491 creator A5060512033 @default.
- W3193396491 creator A5077256674 @default.
- W3193396491 creator A5077802539 @default.
- W3193396491 creator A5088659740 @default.
- W3193396491 creator A5088918018 @default.
- W3193396491 creator A5091203110 @default.
- W3193396491 date "2021-08-15" @default.
- W3193396491 modified "2023-10-18" @default.
- W3193396491 title "Left ventricular unloading during extracorporeal life support for myocardial infarction with cardiogenic shock: surgical venting versus Impella device" @default.
- W3193396491 cites W2004517482 @default.
- W3193396491 cites W2034185700 @default.
- W3193396491 cites W2036539467 @default.
- W3193396491 cites W2100683559 @default.
- W3193396491 cites W2106703370 @default.
- W3193396491 cites W2138373808 @default.
- W3193396491 cites W2161433125 @default.
- W3193396491 cites W2161679538 @default.
- W3193396491 cites W2325538787 @default.
- W3193396491 cites W2344325248 @default.
- W3193396491 cites W2531281781 @default.
- W3193396491 cites W2601373345 @default.
- W3193396491 cites W2789904780 @default.
- W3193396491 cites W2792963059 @default.
- W3193396491 cites W2899955616 @default.
- W3193396491 cites W2902007903 @default.
- W3193396491 cites W2906256331 @default.
- W3193396491 cites W2914956909 @default.
- W3193396491 cites W2920837321 @default.
- W3193396491 cites W2987093168 @default.
- W3193396491 cites W2996215210 @default.
- W3193396491 cites W3092347758 @default.
- W3193396491 doi "https://doi.org/10.1093/icvts/ivab230" @default.
- W3193396491 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34999807" @default.
- W3193396491 hasPublicationYear "2021" @default.
- W3193396491 type Work @default.
- W3193396491 sameAs 3193396491 @default.
- W3193396491 citedByCount "6" @default.
- W3193396491 countsByYear W31933964912022 @default.
- W3193396491 countsByYear W31933964912023 @default.
- W3193396491 crossrefType "journal-article" @default.
- W3193396491 hasAuthorship W3193396491A5008918690 @default.
- W3193396491 hasAuthorship W3193396491A5011836477 @default.
- W3193396491 hasAuthorship W3193396491A5013542824 @default.
- W3193396491 hasAuthorship W3193396491A5015237090 @default.
- W3193396491 hasAuthorship W3193396491A5035687829 @default.
- W3193396491 hasAuthorship W3193396491A5043551594 @default.
- W3193396491 hasAuthorship W3193396491A5045803776 @default.
- W3193396491 hasAuthorship W3193396491A5051809336 @default.
- W3193396491 hasAuthorship W3193396491A5060512033 @default.
- W3193396491 hasAuthorship W3193396491A5077256674 @default.
- W3193396491 hasAuthorship W3193396491A5077802539 @default.
- W3193396491 hasAuthorship W3193396491A5088659740 @default.
- W3193396491 hasAuthorship W3193396491A5088918018 @default.
- W3193396491 hasAuthorship W3193396491A5091203110 @default.
- W3193396491 hasBestOaLocation W31933964911 @default.
- W3193396491 hasConcept C126322002 @default.
- W3193396491 hasConcept C141071460 @default.
- W3193396491 hasConcept C164705383 @default.
- W3193396491 hasConcept C168563851 @default.
- W3193396491 hasConcept C203092338 @default.
- W3193396491 hasConcept C2776850375 @default.
- W3193396491 hasConcept C2776858399 @default.
- W3193396491 hasConcept C2778198053 @default.
- W3193396491 hasConcept C2778774980 @default.
- W3193396491 hasConcept C2779580112 @default.
- W3193396491 hasConcept C2780574415 @default.
- W3193396491 hasConcept C500558357 @default.
- W3193396491 hasConcept C71924100 @default.
- W3193396491 hasConcept C72859922 @default.
- W3193396491 hasConceptScore W3193396491C126322002 @default.
- W3193396491 hasConceptScore W3193396491C141071460 @default.
- W3193396491 hasConceptScore W3193396491C164705383 @default.
- W3193396491 hasConceptScore W3193396491C168563851 @default.
- W3193396491 hasConceptScore W3193396491C203092338 @default.
- W3193396491 hasConceptScore W3193396491C2776850375 @default.
- W3193396491 hasConceptScore W3193396491C2776858399 @default.
- W3193396491 hasConceptScore W3193396491C2778198053 @default.
- W3193396491 hasConceptScore W3193396491C2778774980 @default.
- W3193396491 hasConceptScore W3193396491C2779580112 @default.
- W3193396491 hasConceptScore W3193396491C2780574415 @default.
- W3193396491 hasConceptScore W3193396491C500558357 @default.
- W3193396491 hasConceptScore W3193396491C71924100 @default.
- W3193396491 hasConceptScore W3193396491C72859922 @default.
- W3193396491 hasIssue "1" @default.
- W3193396491 hasLocation W31933964911 @default.
- W3193396491 hasLocation W31933964912 @default.
- W3193396491 hasLocation W31933964913 @default.
- W3193396491 hasOpenAccess W3193396491 @default.