Matches in SemOpenAlex for { <https://semopenalex.org/work/W3193469126> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W3193469126 abstract "BACKGROUND AND AIM: We and others previously observed sex-specific negative associations of maternal paraben concentrations with birth weight (BW) and length (BL). Here, we evaluated whether maternal diet quality modifies these associations. METHODS: Pregnant women ages 18-40 years from Champaign-Urbana, IL provided 5 first-morning urines across pregnancy, which we pooled for analysis of butylparaben, ethylparaben, methylparaben, and propylparaben concentrations. We collected BW and BL data within 24hrs of birth and calculated sex-specific BW-for-gestational-age z-scores (BWz). Women completed 3-month semi-quantitative food frequency questionnaires in early and mid-to-late pregnancy, which we used to calculate mean Alternative Healthy Eating Index 2010 (AHEI-2010) – reflecting foods predictive of chronic disease risk. Multivariable linear regression models evaluated whether associations of parabens with BWz (n=403) and BL (n=429) were modified by AHEI-2010 (dichotomized at the median) and whether the modification varied by fetal sex. We modeled ethylparaben, methylparaben, and propylparaben as continuous variables and butylparaben as zero/non-zero. RESULTS:This predominately non-Hispanic white, college-educated population had lower urinary paraben concentrations than other U.S. women. Median (range) AHEI-2010 was 55.8 (28.1–82.8) out of 110, while BW and BL were 3.5 kg (2.2–4.9) and 50.0 cm (43.9–55.9), respectively. Associations of parabens with birth size only emerged in female newborns whose mothers consumed a poorer diet (AHEI-2010median). In these newborns, each 2-fold increase in maternal methylparaben was associated with 0.1 (95%CI: 0.02, 0.2) lower BWz and 0.2 cm (95%CI: 0.02, 0.3) shorter BL, with similar associations observed for propylparaben. Similarly, female newborns of women who ate a poorer diet and had non-zero butylparaben concentrations had 0.4 (95%CI: 0.1, 0.8) lower BWz and 0.9 cm (95%CI: 0.1, 1.6) shorter BL than women with zero butylparaben concentrations. CONCLUSIONS:Healthier maternal diets may effectively minimize the negative associations between parabens and birth size in female newborns. Additional studies in more diverse populations are needed to confirm these findings. KEYWORDS: Birth outcomes, endocrine disrupting chemicals, phenols" @default.
- W3193469126 created "2021-08-30" @default.
- W3193469126 creator A5021846501 @default.
- W3193469126 creator A5024952055 @default.
- W3193469126 creator A5079448339 @default.
- W3193469126 creator A5081232189 @default.
- W3193469126 date "2021-08-23" @default.
- W3193469126 modified "2023-09-22" @default.
- W3193469126 title "Higher quality maternal diet attenuates negative associations of maternal paraben concentrations with newborn weight and length" @default.
- W3193469126 doi "https://doi.org/10.1289/isee.2021.p-290" @default.
- W3193469126 hasPublicationYear "2021" @default.
- W3193469126 type Work @default.
- W3193469126 sameAs 3193469126 @default.
- W3193469126 citedByCount "0" @default.
- W3193469126 crossrefType "journal-article" @default.
- W3193469126 hasAuthorship W3193469126A5021846501 @default.
- W3193469126 hasAuthorship W3193469126A5024952055 @default.
- W3193469126 hasAuthorship W3193469126A5079448339 @default.
- W3193469126 hasAuthorship W3193469126A5081232189 @default.
- W3193469126 hasConcept C126322002 @default.
- W3193469126 hasConcept C134018914 @default.
- W3193469126 hasConcept C2777415180 @default.
- W3193469126 hasConcept C2779234561 @default.
- W3193469126 hasConcept C2779370918 @default.
- W3193469126 hasConcept C2781087243 @default.
- W3193469126 hasConcept C2908647359 @default.
- W3193469126 hasConcept C31903555 @default.
- W3193469126 hasConcept C42407357 @default.
- W3193469126 hasConcept C54355233 @default.
- W3193469126 hasConcept C67031304 @default.
- W3193469126 hasConcept C71924100 @default.
- W3193469126 hasConcept C86803240 @default.
- W3193469126 hasConcept C99454951 @default.
- W3193469126 hasConceptScore W3193469126C126322002 @default.
- W3193469126 hasConceptScore W3193469126C134018914 @default.
- W3193469126 hasConceptScore W3193469126C2777415180 @default.
- W3193469126 hasConceptScore W3193469126C2779234561 @default.
- W3193469126 hasConceptScore W3193469126C2779370918 @default.
- W3193469126 hasConceptScore W3193469126C2781087243 @default.
- W3193469126 hasConceptScore W3193469126C2908647359 @default.
- W3193469126 hasConceptScore W3193469126C31903555 @default.
- W3193469126 hasConceptScore W3193469126C42407357 @default.
- W3193469126 hasConceptScore W3193469126C54355233 @default.
- W3193469126 hasConceptScore W3193469126C67031304 @default.
- W3193469126 hasConceptScore W3193469126C71924100 @default.
- W3193469126 hasConceptScore W3193469126C86803240 @default.
- W3193469126 hasConceptScore W3193469126C99454951 @default.
- W3193469126 hasIssue "1" @default.
- W3193469126 hasLocation W31934691261 @default.
- W3193469126 hasOpenAccess W3193469126 @default.
- W3193469126 hasPrimaryLocation W31934691261 @default.
- W3193469126 hasRelatedWork W1822654435 @default.
- W3193469126 hasRelatedWork W1987178953 @default.
- W3193469126 hasRelatedWork W2380698512 @default.
- W3193469126 hasRelatedWork W2974484906 @default.
- W3193469126 hasRelatedWork W3022082942 @default.
- W3193469126 hasRelatedWork W3080261720 @default.
- W3193469126 hasRelatedWork W3195538338 @default.
- W3193469126 hasRelatedWork W4211123041 @default.
- W3193469126 hasRelatedWork W4298404810 @default.
- W3193469126 hasRelatedWork W4327546659 @default.
- W3193469126 hasVolume "2021" @default.
- W3193469126 isParatext "false" @default.
- W3193469126 isRetracted "false" @default.
- W3193469126 magId "3193469126" @default.
- W3193469126 workType "article" @default.