FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3193522897> ?p ?o ?g. }

• W3193522897 endingPage "1766" @default.
• W3193522897 startingPage "1766" @default.
• W3193522897 abstract "Background: Claudins are important transmembrane proteins in tight junction. The role of intercellular tight junctions in breast epithelial cells is traditionally thought to be in maintaining polarity and barrier function. However, claudin-4, a tight junction protein, is overexpressed in breast tumor cells compared to normal epithelial cells, which generally corresponds to loss in polarity and can provide valuable information about biology of the tumor. A prospective clinical study was conducted to assess the expression claudin-4 in patients with breast cancer and its correlation with hormone receptors – estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2)-neu.Materials and Methods: The study included 102 biopsy-proven breast carcinoma patients. The biopsy samples were evaluated immunohistochemistry for expression of ER, PR, HER2-neu, and claudin-4. The expression of claudin-4 was correlated with ER, PR, and HER2-neu.Results: In the study, we found that out of 26 cases of high claudin-4, 25 cases (96.15%) were ER negative and P < 0.001, which was significant. Similar results were found with PR-negative cases. Whereas, out of 76 cases with low claudin-4, 54 cases (71.05%) were HER2-neu negative and P = 0.022, which was significant.Conclusions: Claqudin-4 expression has a negative correlation with ER and PR and has a positive correlation with HER2-neu. Hence, it can be effectively utilized as a prognostic and therapeutic marker in breast cancer in the future." @default.
• W3193522897 created "2021-08-30" @default.
• W3193522897 creator A5002488278 @default.
• W3193522897 creator A5020491803 @default.
• W3193522897 creator A5025550348 @default.
• W3193522897 creator A5044368104 @default.
• W3193522897 date "2022-01-01" @default.
• W3193522897 modified "2023-09-27" @default.
• W3193522897 title "Immunoexpression of claudin-4 and correlation with estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2-neu in breast cancer" @default.
• W3193522897 cites W1554042779 @default.
• W3193522897 cites W1971911970 @default.
• W3193522897 cites W1991137546 @default.
• W3193522897 cites W1998777387 @default.
• W3193522897 cites W1999016386 @default.
• W3193522897 cites W2039767026 @default.
• W3193522897 cites W2050899382 @default.
• W3193522897 cites W2054994285 @default.
• W3193522897 cites W2064252617 @default.
• W3193522897 cites W2067052531 @default.
• W3193522897 cites W2072165620 @default.
• W3193522897 cites W2077903543 @default.
• W3193522897 cites W2086828029 @default.
• W3193522897 cites W2096145980 @default.
• W3193522897 cites W2113633750 @default.
• W3193522897 cites W2126824378 @default.
• W3193522897 cites W2127057139 @default.
• W3193522897 cites W2146364391 @default.
• W3193522897 cites W2150688238 @default.
• W3193522897 cites W2161858650 @default.
• W3193522897 cites W2165948908 @default.
• W3193522897 cites W2175975686 @default.
• W3193522897 cites W2493927562 @default.
• W3193522897 cites W2505769839 @default.
• W3193522897 cites W3007536202 @default.
• W3193522897 cites W4376848528 @default.
• W3193522897 doi "https://doi.org/10.4103/jcrt.jcrt_1909_20" @default.
• W3193522897 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36412441" @default.
• W3193522897 hasPublicationYear "2022" @default.
• W3193522897 type Work @default.
• W3193522897 sameAs 3193522897 @default.
• W3193522897 citedByCount "0" @default.
• W3193522897 crossrefType "journal-article" @default.
• W3193522897 hasAuthorship W3193522897A5002488278 @default.
• W3193522897 hasAuthorship W3193522897A5020491803 @default.
• W3193522897 hasAuthorship W3193522897A5025550348 @default.
• W3193522897 hasAuthorship W3193522897A5044368104 @default.
• W3193522897 hasBestOaLocation W31935228971 @default.
• W3193522897 hasConcept C121608353 @default.
• W3193522897 hasConcept C126322002 @default.
• W3193522897 hasConcept C170493617 @default.
• W3193522897 hasConcept C177779419 @default.
• W3193522897 hasConcept C204232928 @default.
• W3193522897 hasConcept C23589133 @default.
• W3193522897 hasConcept C2779438470 @default.
• W3193522897 hasConcept C3018521938 @default.
• W3193522897 hasConcept C502942594 @default.
• W3193522897 hasConcept C51872919 @default.
• W3193522897 hasConcept C530470458 @default.
• W3193522897 hasConcept C71924100 @default.
• W3193522897 hasConcept C84606932 @default.
• W3193522897 hasConcept C86803240 @default.
• W3193522897 hasConcept C95444343 @default.
• W3193522897 hasConcept C98717036 @default.
• W3193522897 hasConceptScore W3193522897C121608353 @default.
• W3193522897 hasConceptScore W3193522897C126322002 @default.
• W3193522897 hasConceptScore W3193522897C170493617 @default.
• W3193522897 hasConceptScore W3193522897C177779419 @default.
• W3193522897 hasConceptScore W3193522897C204232928 @default.
• W3193522897 hasConceptScore W3193522897C23589133 @default.
• W3193522897 hasConceptScore W3193522897C2779438470 @default.
• W3193522897 hasConceptScore W3193522897C3018521938 @default.
• W3193522897 hasConceptScore W3193522897C502942594 @default.
• W3193522897 hasConceptScore W3193522897C51872919 @default.
• W3193522897 hasConceptScore W3193522897C530470458 @default.
• W3193522897 hasConceptScore W3193522897C71924100 @default.
• W3193522897 hasConceptScore W3193522897C84606932 @default.
• W3193522897 hasConceptScore W3193522897C86803240 @default.
• W3193522897 hasConceptScore W3193522897C95444343 @default.
• W3193522897 hasConceptScore W3193522897C98717036 @default.
• W3193522897 hasIssue "6" @default.
• W3193522897 hasLocation W31935228971 @default.
• W3193522897 hasLocation W31935228972 @default.
• W3193522897 hasOpenAccess W3193522897 @default.
• W3193522897 hasPrimaryLocation W31935228971 @default.
• W3193522897 hasRelatedWork W1970614368 @default.
• W3193522897 hasRelatedWork W1995604678 @default.
• W3193522897 hasRelatedWork W2349550873 @default.
• W3193522897 hasRelatedWork W2651034595 @default.
• W3193522897 hasRelatedWork W2765336906 @default.
• W3193522897 hasRelatedWork W2894907676 @default.
• W3193522897 hasRelatedWork W2979609436 @default.
• W3193522897 hasRelatedWork W3109088106 @default.
• W3193522897 hasRelatedWork W3193522897 @default.
• W3193522897 hasRelatedWork W86794624 @default.
• W3193522897 hasVolume "18" @default.
• W3193522897 isParatext "false" @default.
• W3193522897 isRetracted "false" @default.
• W3193522897 magId "3193522897" @default.

• next