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- W3193570374 abstract "Abstract Twelve baicalein derivatives, derivatized with 7‐ester and 8‐aminomethylene groups, were synthesized as cyclin‐dependent kinase 1 (CDK1) inhibitors, by the addition of one of four secondary amines to C‐8, using the Mannich reaction, followed by mono‐esterification with one of three carboxylic acids. Analysis by 1 H‐, 13 C‐NMR, and HMBC spectra, as well as a chemical test, confirmed that the esterification occurred at the 7‐phenolic hydroxyl position of baicalein but not at the 5‐ or 6‐positions." @default.
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- W3193570374 date "2021-08-19" @default.
- W3193570374 modified "2023-09-26" @default.
- W3193570374 title "Synthesis and structure confirmation of 7‐ester‐8‐aminomethylene‐substituted baicalein derivatives" @default.
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- W3193570374 doi "https://doi.org/10.1002/jccs.202100194" @default.
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