FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3193573313> ?p ?o ?g. }

• W3193573313 endingPage "274" @default.
• W3193573313 startingPage "274" @default.
• W3193573313 abstract "BACKGROUND We sought to demonstrate the superiority of a targeted therapy strategy involving high-flow nasal cannula oxygen (HFNCO2) therapy and noninvasive ventilation (NIV) using lung ultrasound score (LUS) in comparison with standard care among patients in the intensive care unit (ICU) who undergo successful weaning to decrease the incidence of extubation failure at both 48 hours and seven days. METHODS During the study period, 98 patients were enrolled in the study, including 49 in the control group and 49 in the treatment group. Patients in the control group and patients with an LUS score <14 points (at low risk of extubation failure) in the treatment group were extubated and received standard preventive care without NIV or HFNCO2. Patients with an LUS score ≥14 points (at high risk of extubation failure) in the treatment group were extubated with a second review of the therapeutic optimization to identify and address any persisting risk factors for postextubation respiratory distress; patients received HFNCO2 therapy combined with sessions of preventive NIV (4-8 hours per day for 4-8 sessions total) for the first 48 hours after extubation. RESULTS In the control group, 13 patients had the LUS scores ≥14 points, while 36 patients had scores <14 points. In the treatment group, 16 patients had the LUS scores ≥14 points, while 33 patients had scores <14 points. Among patients with the LUS score ≥14 points, the extubation failure rate within 48 hours was 30.8% in the control group and 12.5% in the treatment group, constituting a statistically significant difference (P<0.05). Conversely, among patients with an LUS score <14 points, 13.9% in the control group and 9.1% in the treatment group experienced extubation failure (P=0.61). The length of ICU stay (9.4±3.1 days vs. 7.2±2.4 days) was significantly different and the re-intubation rate (at 48 hours: 18.4% vs. 10.2%; seven days: 22.4% vs. 12.2%) significantly varied between the two groups (P<0.05). There was no significant difference in the 28-day mortality rate (6.1% vs. 8.2%) between the control and treatment groups. CONCLUSIONS Among high-risk adults being weaned from mechanical ventilation and assessed by LUS, the NIV+HFNCO2 protocol does not lessen the mortality rate but reduce the length of ICU stay, the rate of extubation failure at both 48 hours and seven days." @default.
• W3193573313 created "2021-08-30" @default.
• W3193573313 creator A5011373849 @default.
• W3193573313 creator A5032405761 @default.
• W3193573313 creator A5033890936 @default.
• W3193573313 creator A5039996976 @default.
• W3193573313 date "2021-01-01" @default.
• W3193573313 modified "2023-09-29" @default.
• W3193573313 title "High-flow nasal cannula oxygen therapy and noninvasive ventilation for preventing extubation failure during weaning from mechanical ventilation assessed by lung ultrasound score: A single-center randomized study" @default.
• W3193573313 cites W1913480475 @default.
• W3193573313 cites W1972351060 @default.
• W3193573313 cites W1987963802 @default.
• W3193573313 cites W2007021449 @default.
• W3193573313 cites W2021568464 @default.
• W3193573313 cites W2048160469 @default.
• W3193573313 cites W2062945788 @default.
• W3193573313 cites W2072036170 @default.
• W3193573313 cites W2074674185 @default.
• W3193573313 cites W2109478667 @default.
• W3193573313 cites W2118871737 @default.
• W3193573313 cites W2119555075 @default.
• W3193573313 cites W2139491315 @default.
• W3193573313 cites W2140066904 @default.
• W3193573313 cites W2142104245 @default.
• W3193573313 cites W2154452972 @default.
• W3193573313 cites W2154881752 @default.
• W3193573313 cites W2157772549 @default.
• W3193573313 cites W2165371495 @default.
• W3193573313 cites W2166715472 @default.
• W3193573313 cites W2170095922 @default.
• W3193573313 cites W2172882542 @default.
• W3193573313 cites W2296794038 @default.
• W3193573313 cites W2528870556 @default.
• W3193573313 cites W2590886410 @default.
• W3193573313 cites W2592177927 @default.
• W3193573313 cites W2605690065 @default.
• W3193573313 cites W2611511676 @default.
• W3193573313 cites W2760069311 @default.
• W3193573313 cites W3016539828 @default.
• W3193573313 cites W3084308367 @default.
• W3193573313 doi "https://doi.org/10.5847/wjem.j.1920-8642.2021.04.004" @default.
• W3193573313 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8390347" @default.
• W3193573313 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34512823" @default.
• W3193573313 hasPublicationYear "2021" @default.
• W3193573313 type Work @default.
• W3193573313 sameAs 3193573313 @default.
• W3193573313 citedByCount "3" @default.
• W3193573313 countsByYear W31935733132022 @default.
• W3193573313 countsByYear W31935733132023 @default.
• W3193573313 crossrefType "journal-article" @default.
• W3193573313 hasAuthorship W3193573313A5011373849 @default.
• W3193573313 hasAuthorship W3193573313A5032405761 @default.
• W3193573313 hasAuthorship W3193573313A5033890936 @default.
• W3193573313 hasAuthorship W3193573313A5039996976 @default.
• W3193573313 hasBestOaLocation W31935733131 @default.
• W3193573313 hasConcept C126322002 @default.
• W3193573313 hasConcept C127413603 @default.
• W3193573313 hasConcept C141071460 @default.
• W3193573313 hasConcept C168563851 @default.
• W3193573313 hasConcept C200457457 @default.
• W3193573313 hasConcept C2777080012 @default.
• W3193573313 hasConcept C2777714996 @default.
• W3193573313 hasConcept C2778074680 @default.
• W3193573313 hasConcept C2780073493 @default.
• W3193573313 hasConcept C2780334268 @default.
• W3193573313 hasConcept C2780630273 @default.
• W3193573313 hasConcept C2780655333 @default.
• W3193573313 hasConcept C2992160955 @default.
• W3193573313 hasConcept C3019440749 @default.
• W3193573313 hasConcept C42219234 @default.
• W3193573313 hasConcept C71924100 @default.
• W3193573313 hasConcept C78519656 @default.
• W3193573313 hasConceptScore W3193573313C126322002 @default.
• W3193573313 hasConceptScore W3193573313C127413603 @default.
• W3193573313 hasConceptScore W3193573313C141071460 @default.
• W3193573313 hasConceptScore W3193573313C168563851 @default.
• W3193573313 hasConceptScore W3193573313C200457457 @default.
• W3193573313 hasConceptScore W3193573313C2777080012 @default.
• W3193573313 hasConceptScore W3193573313C2777714996 @default.
• W3193573313 hasConceptScore W3193573313C2778074680 @default.
• W3193573313 hasConceptScore W3193573313C2780073493 @default.
• W3193573313 hasConceptScore W3193573313C2780334268 @default.
• W3193573313 hasConceptScore W3193573313C2780630273 @default.
• W3193573313 hasConceptScore W3193573313C2780655333 @default.
• W3193573313 hasConceptScore W3193573313C2992160955 @default.
• W3193573313 hasConceptScore W3193573313C3019440749 @default.
• W3193573313 hasConceptScore W3193573313C42219234 @default.
• W3193573313 hasConceptScore W3193573313C71924100 @default.
• W3193573313 hasConceptScore W3193573313C78519656 @default.
• W3193573313 hasIssue "4" @default.
• W3193573313 hasLocation W31935733131 @default.
• W3193573313 hasLocation W31935733132 @default.
• W3193573313 hasOpenAccess W3193573313 @default.
• W3193573313 hasPrimaryLocation W31935733131 @default.
• W3193573313 hasRelatedWork W2351438157 @default.
• W3193573313 hasRelatedWork W2356864385 @default.
• W3193573313 hasRelatedWork W2788267968 @default.
• W3193573313 hasRelatedWork W2905824059 @default.

• next