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• W3193575398 abstract "Bisphenol A (BPA) has been documented as a mediator for a number of health effects, including inflammation, oxidative stress, carcinogenicity, and mood dysfunction. The literature on the role of BPA in inducing altered neurobehavioral response and brain morphology and plausible neuroprotective role of taurine against BPA induced oxidative stress mediated neurotoxicity is limited. Therefore, the present experimental paradigm was set for 21 days to expound the neuroprotective efficacy of taurine against BPA-induced neurotoxicity in zebrafish (Danio rerio) following waterborne exposure. Neurobehavioral studies were conducted by light–dark preference test (LDPT) and novel tank diving test (NTDT). To validate that the neuroprotective efficacy of taurine against BPA-induced neurotoxicity is associated with the modulation of the antioxidant defense system, we have conducted biochemical studies in zebrafish brain. Changes in brain morphology leading to neurobehavioral variations following co-supplementation of BPA and taurine were evaluated by Hoechst staining and cresyl violet staining (CVS) in periventricular gray zone (PGZ) of zebrafish brain. Our findings show that taurine co-supplementation significantly improved the BPA-induced altered scototaxis and explorative behavior of zebrafish. Further, BPA-induced augmented oxidative stress was considerably ameliorated by taurine co-supplementation. Subsequently, our observation also points toward the neuroprotective role of taurine against BPA-induced neuronal pyknosis and chromatin condensation in PGZ of zebrafish brain. In a nutshell, the findings of the current study show the neuroprotective efficacy of taurine against BPA-induced oxidative stress-mediated neurotoxicity. Elucidation of the underlying signaling mechanism of taurine-mediated neuroprotection would provide novel strategies for the prevention/treatment of BPA-persuaded serious neurological consequences." @default.
• W3193575398 created "2021-08-30" @default.
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• W3193575398 date "2021-08-17" @default.
• W3193575398 modified "2023-09-27" @default.
• W3193575398 title "Suppression of bisphenol A‐induced oxidative stress by taurine promotes neuroprotection and restores altered neurobehavioral response in zebrafish ( <i>Danio rerio</i> )" @default.
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• W3193575398 cites W1882289074 @default.
• W3193575398 cites W1915688416 @default.
• W3193575398 cites W1970280705 @default.
• W3193575398 cites W1970760886 @default.
• W3193575398 cites W1985931825 @default.
• W3193575398 cites W1992188021 @default.
• W3193575398 cites W1996482177 @default.
• W3193575398 cites W2003276813 @default.
• W3193575398 cites W2005298105 @default.
• W3193575398 cites W200530653 @default.
• W3193575398 cites W2007064404 @default.
• W3193575398 cites W2008704159 @default.
• W3193575398 cites W2009498931 @default.
• W3193575398 cites W2011885087 @default.
• W3193575398 cites W2019527265 @default.
• W3193575398 cites W2021562900 @default.
• W3193575398 cites W2025699733 @default.
• W3193575398 cites W2037184235 @default.
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• W3193575398 cites W2050268779 @default.
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• W3193575398 cites W2057833729 @default.
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• W3193575398 cites W2085262548 @default.
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• W3193575398 cites W2101422765 @default.
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• W3193575398 cites W2124622312 @default.
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• W3193575398 cites W2138861348 @default.
• W3193575398 cites W2145415601 @default.
• W3193575398 cites W2159054307 @default.
• W3193575398 cites W2159898375 @default.
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• W3193575398 cites W2177909750 @default.
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• W3193575398 doi "https://doi.org/10.1002/tox.23348" @default.
• W3193575398 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34403186" @default.
• W3193575398 hasPublicationYear "2021" @default.
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