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- W3193714122 abstract "In this work we examine a manufacturing process to produce hydrogel tubing for extracorporeal applications. In the first study we examine the methodology to scale-up extrusion printers to inertial flow conditions. We advance bounds to maintain hydrodynamic stability through direct numerical simulation which are verified experimentally. Using these bounds, we develop three different 3D-extrusion printers operating with speeds of up to 12 cm/s. In the second study, we explore the use of these printers by producing biodegradable hydrogel tubing. When reinforced with 1% cellulose fibre, these tubes are sufficiently tough to circulate human blood for 200 h with marginal spallation and display a 6-fold decrease in platelet adhesion. This is a promising first step to reduce cardiovascular complications and to replace single-use plastic tubing in the hospital setting." @default.
- W3193714122 created "2021-08-30" @default.
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- W3193714122 date "2022-01-01" @default.
- W3193714122 modified "2023-09-26" @default.
- W3193714122 title "Fibre-reinforced biocompatible hydrogel to replace single-use plastic tubing in the clinical setting" @default.
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- W3193714122 doi "https://doi.org/10.1016/j.cej.2021.131786" @default.
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