FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3193750231> ?p ?o ?g. }

• W3193750231 endingPage "2043" @default.
• W3193750231 startingPage "2038" @default.
• W3193750231 abstract "Abstract Background: Weight gain and other anthropometric measures on the risk of ovarian cancer for women with BRCA mutations are not known. We conducted a prospective analysis of weight change since age 18, height, body mass index (BMI) at age 18, and current BMI and the risk of developing ovarian cancer among BRCA1 and BRCA2 mutation carriers. Methods: In this prospective cohort study, height, weight, and weight at age 18 were collected at study enrollment. Weight was updated biennially. Cox proportional hazards models were used to estimate the hazard ratio (HR) and 95% confidence intervals (CI) for ovarian cancer. Results: This study followed 4,340 women prospectively. There were 121 incident cases of ovarian cancer. Weight gain of more than 20 kg since age 18 was associated with a 2-fold increased risk of ovarian cancer, compared with women who maintained a stable weight (HR, 2.00; 95% CI, 1.13–3.54; P = 0.02). Current BMI of 26.5 kg/m2 or greater was associated with an increased risk of ovarian cancer in BRCA1 mutation carriers, compared with those with a BMI less than 20.8 kg/m2 (Q4 vs. Q1 HR, 2.13; 95% CI, 1.04–4.36; P = 0.04). There were no significant associations between height or BMI at age 18 and risk of ovarian cancer. Conclusions: Adult weight gain is a risk factor for ovarian cancer in women with a BRCA1 or BRCA2 mutation. Impact: These findings emphasize the importance of maintaining a healthy body weight throughout adulthood in women at high risk for ovarian cancer." @default.
• W3193750231 created "2021-08-30" @default.
• W3193750231 creator A5015052494 @default.
• W3193750231 creator A5024416023 @default.
• W3193750231 creator A5026033317 @default.
• W3193750231 creator A5029874203 @default.
• W3193750231 creator A5033831143 @default.
• W3193750231 creator A5038322204 @default.
• W3193750231 creator A5038895170 @default.
• W3193750231 creator A5046339613 @default.
• W3193750231 creator A5051532432 @default.
• W3193750231 creator A5057209864 @default.
• W3193750231 creator A5062123247 @default.
• W3193750231 creator A5065070297 @default.
• W3193750231 creator A5065551274 @default.
• W3193750231 creator A5065891328 @default.
• W3193750231 creator A5077863833 @default.
• W3193750231 creator A5082993956 @default.
• W3193750231 creator A5087749880 @default.
• W3193750231 creator A5088516335 @default.
• W3193750231 creator A5089598316 @default.
• W3193750231 date "2021-08-23" @default.
• W3193750231 modified "2023-10-16" @default.
• W3193750231 title "Weight Gain and the Risk of Ovarian Cancer in <i>BRCA1</i> and <i>BRCA2</i> Mutation Carriers" @default.
• W3193750231 cites W1527338770 @default.
• W3193750231 cites W1563140450 @default.
• W3193750231 cites W1917788503 @default.
• W3193750231 cites W1965047367 @default.
• W3193750231 cites W1984374784 @default.
• W3193750231 cites W2019067804 @default.
• W3193750231 cites W2054785621 @default.
• W3193750231 cites W2077796933 @default.
• W3193750231 cites W2077980077 @default.
• W3193750231 cites W2124985930 @default.
• W3193750231 cites W2126877871 @default.
• W3193750231 cites W2142296587 @default.
• W3193750231 cites W2462819743 @default.
• W3193750231 cites W2579423964 @default.
• W3193750231 cites W2592578600 @default.
• W3193750231 cites W2627871710 @default.
• W3193750231 cites W2803852062 @default.
• W3193750231 cites W2894385791 @default.
• W3193750231 cites W2896212671 @default.
• W3193750231 cites W2897901911 @default.
• W3193750231 cites W2906215854 @default.
• W3193750231 cites W2952644236 @default.
• W3193750231 cites W2982195821 @default.
• W3193750231 cites W3016007555 @default.
• W3193750231 cites W4237383128 @default.
• W3193750231 cites W4251987491 @default.
• W3193750231 cites W4322008798 @default.
• W3193750231 doi "https://doi.org/10.1158/1055-9965.epi-21-0296" @default.
• W3193750231 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34426412" @default.
• W3193750231 hasPublicationYear "2021" @default.
• W3193750231 type Work @default.
• W3193750231 sameAs 3193750231 @default.
• W3193750231 citedByCount "5" @default.
• W3193750231 countsByYear W31937502312022 @default.
• W3193750231 countsByYear W31937502312023 @default.
• W3193750231 crossrefType "journal-article" @default.
• W3193750231 hasAuthorship W3193750231A5015052494 @default.
• W3193750231 hasAuthorship W3193750231A5024416023 @default.
• W3193750231 hasAuthorship W3193750231A5026033317 @default.
• W3193750231 hasAuthorship W3193750231A5029874203 @default.
• W3193750231 hasAuthorship W3193750231A5033831143 @default.
• W3193750231 hasAuthorship W3193750231A5038322204 @default.
• W3193750231 hasAuthorship W3193750231A5038895170 @default.
• W3193750231 hasAuthorship W3193750231A5046339613 @default.
• W3193750231 hasAuthorship W3193750231A5051532432 @default.
• W3193750231 hasAuthorship W3193750231A5057209864 @default.
• W3193750231 hasAuthorship W3193750231A5062123247 @default.
• W3193750231 hasAuthorship W3193750231A5065070297 @default.
• W3193750231 hasAuthorship W3193750231A5065551274 @default.
• W3193750231 hasAuthorship W3193750231A5065891328 @default.
• W3193750231 hasAuthorship W3193750231A5077863833 @default.
• W3193750231 hasAuthorship W3193750231A5082993956 @default.
• W3193750231 hasAuthorship W3193750231A5087749880 @default.
• W3193750231 hasAuthorship W3193750231A5088516335 @default.
• W3193750231 hasAuthorship W3193750231A5089598316 @default.
• W3193750231 hasBestOaLocation W31937502311 @default.
• W3193750231 hasConcept C121608353 @default.
• W3193750231 hasConcept C126322002 @default.
• W3193750231 hasConcept C143998085 @default.
• W3193750231 hasConcept C147583825 @default.
• W3193750231 hasConcept C188816634 @default.
• W3193750231 hasConcept C207103383 @default.
• W3193750231 hasConcept C2780194787 @default.
• W3193750231 hasConcept C2780221984 @default.
• W3193750231 hasConcept C2780320433 @default.
• W3193750231 hasConcept C2780427987 @default.
• W3193750231 hasConcept C29456083 @default.
• W3193750231 hasConcept C3017894415 @default.
• W3193750231 hasConcept C44249647 @default.
• W3193750231 hasConcept C50382708 @default.
• W3193750231 hasConcept C50440223 @default.
• W3193750231 hasConcept C511355011 @default.
• W3193750231 hasConcept C544821477 @default.
• W3193750231 hasConcept C61427482 @default.

• next