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- W3193845981 abstract "H2S is an endogenous gaseous signal molecule with cell protective function, which plays a critical part in many physiological and pathological processes. On the one hand, abnormal fluctuations of the concentration of hydrogen sulfide in the human body are closely related to diseases such as Down's syndrome, Alzheimer's, diabetes and cirrhosis of the liver. On the other hand, acts as an antioxidant in the body, hydrogen sulfide can protect cells from damage caused by reactive oxygen species. Therefore, it is indispensible to detect hydrogen sulfide in living organisms. A fluorescent probe—NX-H2S, was constructed using azide group as the recognition group and naphthalimide as the framework. The spectroscopic properties of the probe were explored comprehensively. The experiment results show that NX-H2S exhibits not only a fast response (5 min) but also excellent sensitivity and selectivity toward H2S. In addition to the rapid detection of H2S in vitro, NX-H2S can also be successfully applied to the fluorescence imaging analysis of endogenous and exogenous H2S in living cells." @default.
- W3193845981 created "2021-08-30" @default.
- W3193845981 creator A5090505321 @default.
- W3193845981 date "2021-08-01" @default.
- W3193845981 modified "2023-09-25" @default.
- W3193845981 title "Design and application of a fluorescent probe for rapid detection of H2S" @default.
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- W3193845981 doi "https://doi.org/10.1088/1742-6596/2009/1/012077" @default.
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