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• W3193943764 abstract "We would like to thank Scarpino and colleagues for their very interesting addition to the field of continuous interpretation of somatosensory evoked potentials (SSEPs)1.Scarpino M. Lolli F. Lanzo G. et al.SSEP amplitude accurately predicts both good and poor neurological outcome early after cardiac arrest; a post-hoc analysis of the ProNeCA multicentre study.Resuscitation. 2021; 163: 162-171Abstract Full Text Full Text PDF PubMed Scopus (14) Google Scholar and their comments on our recently published manuscript.2.van Soest T.M. van Rootselaar A.-F. Admiraal M.M. Potters W.V. Koelman J.H.M.T. Horn J. SSEP amplitudes add information for prognostication in postanoxic coma.Resuscitation. 2021; 163: 172-175Abstract Full Text Full Text PDF PubMed Scopus (6) Google Scholar, 3.Scarponi Maenia Grippo Antonello Sandroni Claudio ProNeCA study groupSSEP amplitude for prognostication in post-anoxic coma: a further step towards standardisation.Resuscitation. 2021; Abstract Full Text Full Text PDF Scopus (1) Google Scholar Scarpino et al. question whether we missed the opportunity to evaluate the ability of a high SSEP amplitude to predict a good neurological outcome. This is a very interesting suggestion as we do agree that reliable prediction of a good outcome can also be important. However, our data did not allow such an analysis. The data we used were collected in daily clinical care, in which a SSEP was recorded in patients who did not regain consciousness after clearance of sedative mediation. Therefore, the number of patients with a good outcome is very low. To investigate the value of a high amplitude SSEP for prediction of good outcome, a SSEP registration early after admission, ideally between 12–24 h, should be performed. Furthermore, we agree that a standardized method of amplitude assessment is needed before this parameter can be incorporated in (inter)national recommendations for prognostication. As different methods were described, we decided to compare all methods reported in our study. The N20/P25 method currently seems to be the best option. This method is also supported by the results of the Italian study by Scarpino.1.Scarpino M. Lolli F. Lanzo G. et al.SSEP amplitude accurately predicts both good and poor neurological outcome early after cardiac arrest; a post-hoc analysis of the ProNeCA multicentre study.Resuscitation. 2021; 163: 162-171Abstract Full Text Full Text PDF PubMed Scopus (14) Google Scholar We think it is important that this method is further validated in future large studies. The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper." @default.
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• W3193943764 date "2021-10-01" @default.
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• W3193943764 title "Reply to Scarpino et al., SSEP amplitude for prognostication in post-anoxic coma: A further step towards standardization" @default.
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• W3193943764 doi "https://doi.org/10.1016/j.resuscitation.2021.08.030" @default.
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