FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3194438746> ?p ?o ?g. }

• W3194438746 endingPage "126842" @default.
• W3194438746 startingPage "126842" @default.
• W3194438746 abstract "Aluminum trichloride (AlCl3) exposure was proven to encourage some behavioral deficits and eventually induces anxiety and depression in rodents animals. Therefore, this experiment aimed to scout about the effects of pomegranate juice on anxiety- and depression-like behaviors caused by AlCl3 in male mice.Six groups of male mice were administrated orally for 35 days by PJ and AlCl3. The control group (G-I) received tap water, while the PJ groups (G-II and G-III) were treated with 20 % and 40 % PJ, respectively. The AlCl3 group (G-IV) was treated with 400 mg/kg/day of AlCl3, and the last two groups (G-V and G-VI) were treated with AlCl3 and 20 % PJ or 40 % PJ, respectively. Then, the open-field (O-F), elevated plus maze (EPM), tail suspension (TS), forced swimming (FS), and light/dark box (L/DB) tests were applied for anxiety- and depression-like behavior studies. In addition, neurotransmitters and oxidative parameters in the brain were evaluated. The plasma cortisol was measured at the end of the experiment.Behavioral analyses showed that PJ inhibited AlCl3-induced depressive and anxiogenic effects in the O-F, EPM, TS, FS, L/DB tests. In addition, neurochemical results indicated that PJ at 20 % concentration minimized the AlCl3 toxicity on dopamine (DOP), serotonin (SER), and acetylcholinesterase (AChE) levels in the for-brain of male mice. Moreover, PJ moderated the AlCl3 effects by decreasing the level of thiobarbituric acid reactive substances (TBARS), and enhancing catalase (CAT), superoxide dismutase (SOD), glutathione S-transferase (GST) and glutathione (GSH) activities. The plasma cortisol increased in male mice treated with AlCl3 and in a group treated with a high dose of PJ.Our results proposed that the anxiety- and depression-like behaviors induced by AlCl3 exposure in male mice can be ameliorated by PJ treatment, probably through the inhibition of oxidative damage and minimizing the changes in neurotransmitters and hormonal activity." @default.
• W3194438746 created "2021-08-30" @default.
• W3194438746 creator A5016490352 @default.
• W3194438746 creator A5027668614 @default.
• W3194438746 date "2021-12-01" @default.
• W3194438746 modified "2023-09-24" @default.
• W3194438746 title "Pomegranate juice moderates anxiety- and depression-like behaviors in AlCl3-treated male mice" @default.
• W3194438746 cites W1581414347 @default.
• W3194438746 cites W1750690213 @default.
• W3194438746 cites W1765407951 @default.
• W3194438746 cites W1964160578 @default.
• W3194438746 cites W1971048984 @default.
• W3194438746 cites W1974409272 @default.
• W3194438746 cites W1977545257 @default.
• W3194438746 cites W1978830885 @default.
• W3194438746 cites W1983310681 @default.
• W3194438746 cites W2012508579 @default.
• W3194438746 cites W2050792136 @default.
• W3194438746 cites W2071862234 @default.
• W3194438746 cites W2099668461 @default.
• W3194438746 cites W2103629466 @default.
• W3194438746 cites W2113313289 @default.
• W3194438746 cites W2146737231 @default.
• W3194438746 cites W2163736026 @default.
• W3194438746 cites W2169981773 @default.
• W3194438746 cites W2258094856 @default.
• W3194438746 cites W2341087932 @default.
• W3194438746 cites W2398831259 @default.
• W3194438746 cites W2491400549 @default.
• W3194438746 cites W2528323937 @default.
• W3194438746 cites W2539506103 @default.
• W3194438746 cites W2604153912 @default.
• W3194438746 cites W2612921975 @default.
• W3194438746 cites W2769578311 @default.
• W3194438746 cites W2790824113 @default.
• W3194438746 cites W2801432701 @default.
• W3194438746 cites W2888290218 @default.
• W3194438746 cites W2891479021 @default.
• W3194438746 cites W2901764824 @default.
• W3194438746 cites W2903511508 @default.
• W3194438746 cites W2912455234 @default.
• W3194438746 cites W2942554289 @default.
• W3194438746 cites W2942819987 @default.
• W3194438746 cites W2943834574 @default.
• W3194438746 cites W2947783877 @default.
• W3194438746 cites W2948062318 @default.
• W3194438746 cites W2962734343 @default.
• W3194438746 cites W2982337704 @default.
• W3194438746 cites W2990575572 @default.
• W3194438746 cites W2998057409 @default.
• W3194438746 cites W3001899170 @default.
• W3194438746 cites W3012348212 @default.
• W3194438746 cites W3016116357 @default.
• W3194438746 cites W3029782229 @default.
• W3194438746 cites W3030915132 @default.
• W3194438746 cites W3036675813 @default.
• W3194438746 cites W3047661272 @default.
• W3194438746 cites W3088485949 @default.
• W3194438746 cites W3090698630 @default.
• W3194438746 cites W4206726746 @default.
• W3194438746 doi "https://doi.org/10.1016/j.jtemb.2021.126842" @default.
• W3194438746 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34418746" @default.
• W3194438746 hasPublicationYear "2021" @default.
• W3194438746 type Work @default.
• W3194438746 sameAs 3194438746 @default.
• W3194438746 citedByCount "4" @default.
• W3194438746 countsByYear W31944387462022 @default.
• W3194438746 countsByYear W31944387462023 @default.
• W3194438746 crossrefType "journal-article" @default.
• W3194438746 hasAuthorship W3194438746A5016490352 @default.
• W3194438746 hasAuthorship W3194438746A5027668614 @default.
• W3194438746 hasConcept C118552586 @default.
• W3194438746 hasConcept C126322002 @default.
• W3194438746 hasConcept C134018914 @default.
• W3194438746 hasConcept C136569192 @default.
• W3194438746 hasConcept C15744967 @default.
• W3194438746 hasConcept C170493617 @default.
• W3194438746 hasConcept C173586616 @default.
• W3194438746 hasConcept C181199279 @default.
• W3194438746 hasConcept C185592680 @default.
• W3194438746 hasConcept C205044023 @default.
• W3194438746 hasConcept C25876315 @default.
• W3194438746 hasConcept C2775838275 @default.
• W3194438746 hasConcept C2776151105 @default.
• W3194438746 hasConcept C2777352226 @default.
• W3194438746 hasConcept C2777765862 @default.
• W3194438746 hasConcept C2778816929 @default.
• W3194438746 hasConcept C2778979269 @default.
• W3194438746 hasConcept C2779059548 @default.
• W3194438746 hasConcept C2779085643 @default.
• W3194438746 hasConcept C2779177272 @default.
• W3194438746 hasConcept C2780829032 @default.
• W3194438746 hasConcept C2781001258 @default.
• W3194438746 hasConcept C538909803 @default.
• W3194438746 hasConcept C55493867 @default.
• W3194438746 hasConcept C558461103 @default.
• W3194438746 hasConcept C71924100 @default.
• W3194438746 hasConceptScore W3194438746C118552586 @default.

• next