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- W31944899 abstract "Some reports have suggested that methylation and demethylation of compounds related to 6-hydroxydopamine may be involved in endogenous mental disorder. We report the synthesis of 3,4-dimethyoxyphenethylamine (DMPEA) and 2,4,5-trimethoxyphenylisopropylamine (TMA-2) with each methoxyl group separately labeled with /sup 14/C. The rate and percent demethylation of these two compounds, with five labeled positions, were determined in the rat. The results suggest that TMA-2 might be metabolized to a hydroquinone in vivo; a similar metabolic intermediate of the psychoactive compound DOM is known to give rise in vitro to an indole." @default.
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- W31944899 date "1976-01-01" @default.
- W31944899 modified "2023-09-24" @default.
- W31944899 title "Quantitative measurement of demethylation of /sup 14/C-methoxyl labeled DMPEA and TMA-2 in rats" @default.
- W31944899 hasPublicationYear "1976" @default.
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