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- W3194655833 abstract "Porphyrins have been extensively used in clinical phototherapy. However, most of them exhibited absorption below 700 nm. We report conjugated tri-porphyrins showing absorption within a biological phototherapy window (700–850 nm). On this basis, bioinspired intracellular pH-sensitive metallo-supramolecular nanoparticles (NPs) are designed. They provide the simultaneous photothermal therapy and chemotherapy. After treatment by tail vein injection, the tumor was completely relieved without recurrence in a course of 27 days. These bioinspired intracellular pH-sensitive metallo-supramolecular NPs show excellent potential application in near-infrared photoacoustic imaging-guided chemo-photothermal combined therapy." @default.
- W3194655833 created "2021-08-30" @default.
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- W3194655833 date "2021-08-26" @default.
- W3194655833 modified "2023-10-16" @default.
- W3194655833 title "Bioinspired Conjugated Tri-Porphyrin-Based Intracellular pH-Sensitive Metallo-Supramolecular Nanoparticles for Near-Infrared Photoacoustic Imaging-Guided Chemo- and Photothermal Combined Therapy" @default.
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- W3194655833 doi "https://doi.org/10.1021/acsbiomaterials.1c00597" @default.
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