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- W3194657730 abstract "Background: There are several case reports suggesting that G-CSFs may, in rare conditions, produce serious side effects, such as vasculitis. Materials & methods: A systematic search was conducted in Medline via PubMed, Embase and Cochrane Library to describe this unusual side effect to raise awareness among clinicians for early recognition and treatment. Results: Fifty-seven patients were analyzed. The most prevalent cancer type was breast cancer (47%). Long-acting G-CSF was used in 38 patients (67%). Only 47% of patients were treated with steroids. Conclusion: Although the benefit of G-CSF treatment outweighs the potential damage, oncologists should consider the possibility of triggering a vascular toxicity and try to identify patients at increased risk for this side effect." @default.
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- W3194657730 date "2021-11-01" @default.
- W3194657730 modified "2023-09-24" @default.
- W3194657730 title "G-CSF and G-CSF-related vasculitis: a systematic review of the literature and intriguing future research perspectives" @default.
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- W3194657730 doi "https://doi.org/10.2217/fon-2021-0701" @default.
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