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• W3194674752 abstract "Axonal polyneuropathy is the main feature of hereditary transthyretin amyloidosis (ATTRv). Nerve morphological abnormalities have been reported, but longitudinal changes have never been assessed. We performed a prospective widespread nerve ultrasound evaluation and nerve cross-sectional area (CSA) was compared with baseline data in both ATTRv patients and pre-symptomatic carriers. Thirty-eight subjects were evaluated (mean follow-up 17.1 months), among them 21 had polyneuropathy while 17 were pre-symptomatic carriers. CSA significantly increased at brachial plexus in both groups (p = 0.008 and p = 0.012) pointing to progressive brachial plexus enlargement as a longitudinal biomarker of both disease progression and disease occurrence in pre-symptomatic carriers." @default.
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• W3194674752 date "2021-08-19" @default.
• W3194674752 modified "2023-10-16" @default.
• W3194674752 title "Progressive brachial plexus enlargement in hereditary transthyretin amyloidosis" @default.
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• W3194674752 doi "https://doi.org/10.1007/s00415-021-10754-9" @default.
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