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- W3194819753 abstract "目的:通过对人肠道病毒D68型(EV-D68)衣壳蛋白VP1理化性质、结构功能和B细胞表位分析,获取候选疫苗肽段用于后期疫苗研制.方法:应用Bioedit软件、Netphos和ExPASy等在线工具分析EV-D68 VP1蛋白氨基酸序列.结果:EV-D68 VP1蛋白是等电点为8.73、相对分子量34.0 kD的亲水性蛋白质,具有35个可能的磷酸化位点,无信号肽和跨膜区,二级结构中不规则卷区有最高比例,α-螺旋和β-折叠散落在蛋白中;预测VP1蛋白具有多个可能的B细胞表位.结论:本研究分析了EV-D68 VP1的基本理化性质,结构功能和可能的B细胞表位,筛选了B细胞表位肽段,为EV-D68的进一步研究和疫苗的制备奠定基础." @default.
- W3194819753 created "2021-08-30" @default.
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- W3194819753 date "2020-01-01" @default.
- W3194819753 modified "2023-09-23" @default.
- W3194819753 title "Bioinformatics analysis of EV-D68 VP1 protein and prediction and screening of candidate vaccine epitope peptide segments" @default.
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