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• W3194977930 abstract "The endothelin-B (ETB) receptor mediates vasodilation in young women, an effect lost following menopause. It is unclear whether these alterations are due to aging or changes in estradiol (E2). During endogenous hormone suppression (GnRH antagonist), blockade of ETB receptors enhanced cutaneous microvascular vasodilation. However, during E2 administration, blockade of ETB receptors attenuated vasodilation, indicating that the ETB receptor mediates dilation in the presence of E2. In young women, ETB receptors mediate vasodilation in the presence of E2, an effect that is lost when E2 is suppressed." @default.
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• W3194977930 date "2021-09-01" @default.
• W3194977930 modified "2023-09-27" @default.
• W3194977930 title "ET_B receptor-mediated vasodilation is regulated by estradiol in young women" @default.
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• W3194977930 doi "https://doi.org/10.1152/ajpheart.00087.2021" @default.
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