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• W3195085412 abstract "Abstract A better understanding of the mechanical behavior of biological materials has the potential to improve clinical decision making, guide medical protocol, and inform engineering design. Biological materials are fascinating because they often have a complex hierarchical structure and, unlike traditional engineering materials, they often adapt in response to changes in their environment. However, modeling biological materials is challenging because many of the fundamental mechanisms guiding material growth and response to intervention are unknown. And, even when behavior is well understood on one spatial scale, it is often poorly understood on others. Critically, some biological materials undergo fracture, and some cannot be conveniently categorized as either fully continuous or fully discrete. Recently, the peridynamic framework has been adapted and extended to address challenges specifically relevant to modeling biological materials. In this chapter, we summarize several of these recent advances. We highlight work on the subcellular, cellular, and macroscale, and show examples of the peridynamic framework in a multiscale model. The work presented here represents a starting point for significant future investigation toward understanding, predicting, and ultimately controlling the mechanical behavior of biological materials." @default.
• W3195085412 created "2021-08-30" @default.
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• W3195085412 date "2021-01-01" @default.
• W3195085412 modified "2023-09-23" @default.
• W3195085412 title "Modeling biological materials with peridynamics" @default.
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• W3195085412 doi "https://doi.org/10.1016/b978-0-12-820069-8.00005-6" @default.
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