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- W3195165764 abstract "Bioactive glass (70 mol% Si and 30% Ca; 70S30C) has been used as tissue engineering scaffolds in various research despite its brittleness due to its easy-to-replicate formula, extensive interconnected pores and natural bone bonding property of bioactive glass (BG). Thai silk fibroin (SF) is natural polymer with many desirable properties; biocompatibility, mechanical strength, biodegradability. Using BG-SF hybrid scaffolds could employ the positive effects of both bioactive glass and silk fibroin. Serving as bone scaffolds, BG-SF scaffolds must resist compression and other types of mechanical load depending on the application. This study fabricates scaffolds with various ratios of BG:SF (BG:SF; 90:10, 80:20 with 100:0 as control), and their stress-strain profiles were investigated. As expected, the scaffolds with highest BG content exhibited the curve resembling that of porous foam while the elastomeric stress-strain profile was becoming more evident when the SF content was increased. This study hence demonstrated fine-tuning mechanical properties of the BG using locally enriched SF." @default.
- W3195165764 created "2021-08-30" @default.
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- W3195165764 date "2021-08-01" @default.
- W3195165764 modified "2023-09-25" @default.
- W3195165764 title "Effect of Thai Silk Fibroin on Mechanical Properties of Bioactive Glass Silk Fibroin Hybrid Bone Scaffolds" @default.
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- W3195165764 doi "https://doi.org/10.1088/1757-899x/1163/1/012009" @default.
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